A5080320934- Spine and Intervertebral Disc Pathology
- Medical Imaging and Analysis
- Hip and Femur Fractures
- Musculoskeletal pain and rehabilitation
- Pelvic and Acetabular Injuries
- Cardiac, Anesthesia and Surgical Outcomes
- Frailty in Older Adults
- Spinal Fractures and Fixation Techniques
- Spondyloarthritis Studies and Treatments
- Acute Ischemic Stroke Management
- Orthopaedic implants and arthroplasty
- Traumatic Brain Injury Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Anesthesia and Pain Management
- Management of metastatic bone disease
- Pain Management and Treatment
- Bone and Joint Diseases
- Opioid Use Disorder Treatment
- Botulinum Toxin and Related Neurological Disorders
- Medical Malpractice and Liability Issues
- Cardiac Arrest and Resuscitation
- Pregnancy-related medical research
- Pain Management and Opioid Use
- Total Knee Arthroplasty Outcomes
- Medical Coding and Health Information
University of Southern California
2020-2023
Keck Hospital of USC
2021-2023
University of California, San Francisco
2018-2022
Neurological Surgery
2020-2021
Oxford University Press (United Kingdom)
2020
OBJECTIVE Frailty is a clinical state of increased vulnerability due to age-associated decline and has been well established as perioperative risk factor. Geriatric patients have higher frailty, incidence brain cancer, postoperative complication rates compared nongeriatric patients. Yet, literature describing the effects frailty on short- long-term complications in geriatric limited. In this study, authors evaluate receiving cranial neurosurgery for primary CNS neoplasm. METHODS The...
Background There is an interplay between the intervertebral disc (IVD) and adjacent bone marrow that may play a role in development of IVD degeneration might influence chronic lower back pain (CLBP). Purpose To apply novel quantitative MRI techniques to assess relationship vertebral fat (BMF) biochemical changes IVD. Study Type Prospective. Subjects Forty‐six subjects (26 female 20 male) with mean age 47.3 ± 12.0 years. Field Strength/Sequence 3 T MRI; combined 1ρ 2 mapping pulse sequence 3D...
Background: Bone marrow fat (BMF) fraction quantification in vertebral bodies is used as a novel imaging biomarker to assess and characterize chronic lower back pain. However, manual segmentation of time consuming laborious. Purpose: 1) Develop deep learning pipeline for using quantitative water-fat MRI. 2) Compare BMF measurements between automatic methods performance. Materials Methods: In this retrospective study, MR images 3D spoiled gradient-recalled echo (SPGR) sequence with Iterative...
OBJECTIVE Pituitary adenomas (PAs) are among the most common intracranial tumors. Understanding clinical effects of various modifiable risk factors (MRFs) and nonmodifiable (NMRFs) is important in guiding proper treatment, yet there limited evidence outlining influence MRFs NMRFs on outcomes PA resection. The aim this study was to analyze patients undergoing resection for PAs. METHODS Using 2016 2017 National Readmission Database, authors identified a cohort 9472 microscopic or endoscopic...
Review.A comparative overview of cost-effectiveness between minimally invasive versus and equivalent open spinal surgeries.A literature search using PubMed was performed to identify articles interest. To maximize the capture studies in our initial search, we combined variants terms "cost," "minimally invasive," "spine," "spinal fusion," "decompression" as either keywords or MeSH terms. PearlDiver database queried for surgery (MIS; endoscopic percutaneous) reimbursements Q3 2015 Q2 2018.In...
Vertebral endplate bone marrow lesions, visualized on magnetic resonance imaging (MRI) as Modic changes (MC), are associated with chronic low back pain (cLBP). Since guidelines recommend against routine spinal MRI for cLBP in primary care, MC may be underdiagnosed. Serum biomarkers would allow early diagnosis, inform clinical care decisions, and supplement treatment monitoring. We aimed to discover the blood serum that correlate pathophysiological processes. For this single-site...
Abstract Purpose Vertebral endplate bone marrow lesions (“Modic changes”, MC) are associated with chronic low back pain (CLBP). Bone composition in MC is poorly understood. The goals of this study were to: (1) measure fat fraction (BMF) CLBP patients using water–fat MRI and (2) assess the relationship between BMF measurements patient-reported clinical characteristics. Methods In cross-sectional study, 42 (men, n = 21; age, 48 ± 12.4 years) 18 asymptomatic controls 10; 42.7 12.8 underwent 3 T...
OBJECTIVE Concussions are a form of mild traumatic brain injury (mTBI) that most commonly occur after blunt trauma to the head and may result in temporary loss consciousness. These patients typically comanaged by neurocritical care specialists, neurologists, neurosurgeons depending on severity disease. The purpose this study was twofold: 1) evaluate how patient demographic characteristics impact development novel psychiatric disorders (NPDs) mTBI; 2) develop screening recommendations...
Study Design. This is an in vitro study of bovine disc cells exposed to pulsed electromagnetic fields. Objective. The purpose the present was investigate whether fields (PEMF) effects on expression interleukin-6 (IL-6) mediated by two known inflammation regulators, nuclear factor-κB (NF-κβ) and phosphorylated mitogen-activated protein kinase p38 (p38-MAPK) signaling pathways Summary Background Data. Inflammatory cytokines play a dominant role pathogenesis degeneration. Increasing evidence...
Retrospective cohort study.The impact of modifiable risk factors (MRFs) on complications, costs, and readmission rates at 30, 90, 180-days following lumbar spine fusion.Patients with fusions within the 2016-2017 Nationwide Readmissions Database (NRD). Patients were stratified by MRFs: Alcohol use, tobacco/nicotine nutritional malnourishment, dyslipidemia, primary hypertension. Differences in non-elective rates, length stay compared between MRFs non-MRF group. Statistical analysis was...
BACKGROUND: The Centers for Medicare and Medicaid Services (CMS) hierarchical condition category (HCC) coding is a risk adjustment model that allows the estimation of risk—and cost—associated with health care provision. Current models may not include key factors fully delineate associated spine surgery. OBJECTIVE: To augment CMS HCC methodology socioeconomic data to improve its predictive capabilities METHODS: National Inpatient Sample was queried spinal fusion, merged county-level coverage...
INTRODUCTION: Frailty is a clinical state of increased vulnerability due to age-associated decline and has been well established as perioperative risk factor. Yet, literature describing the effects frailty on short- long-term complications in geriatric patients limited. METHODS: The authors conducted retrospective cohort study between 2010 2017 by using Nationwide Readmission Database. Demographics were queried at primary admission, readmissions analyzed 30-, 90-, 180-day intervals....
Cementless fixation during total hip arthroplasty (THA) is the predominant mode of utilized for both acetabular and femoral components elective primary THAs performed in United States. This study aims to compare early complication readmission rates between THA patients receiving cemented versus cementless fixation. The 2016–2017 National Readmissions Database was queried identify undergoing THA. Postoperative at 30, 90, 180 days were compared cohorts. Univariate analysis conducted...
Retrospective cohort study using the 2013-2017 National Readmission Database.The aim of this was to quantify influence body mass index (BMI) on complication and readmission rates following lumbar spine fusion.Compared controls, patients with BMI ≥35 had greater odds readmission, infection, wound complications fusion.Patients who underwent elective fusion within population-based sample were considered for inclusion. Exclusion criteria included nonelective fusions, malnourished, anorexic, or...
Modifiable risk factors (MRFs) represent patient variables associated with increased complication rates that may be prevented. There exists a paucity of studies comprehensively analyze MRF subgroups and their independent association postoperative complications in patients undergoing cervical spine surgery. Therefore, the purpose this study is to compare outcomes between receiving surgery reported MRFs.Retrospective analysis Nationwide Readmissions Database (NRD) from years 2016 2017,...
OBJECTIVE Spine surgery is especially susceptible to malpractice claims. Critics of the US medical liability system argue that it drives up costs, whereas proponents deters negligence. Here, authors study relationship between claim density and outcomes. METHODS The following methods were used: 1) National Practitioner Data Bank was used determine number claims per 100 physicians, by state, 2005 2010; 2) Nationwide Inpatient Sample queried for spinal fusion patients; 3) Area Resource File...
Background Context Several studies have shown that factors such as insurance type and patient income are associated with different readmission rates following certain orthopaedic procedures. The literature, however, remains sparse regard to these demographic characteristics their associations perioperative lumbar spine fusion outcomes. Purpose purpose of this study was assess the between hospital type, median both 30-day complication fusion. Patient Sample Patients who underwent primary (n =...
Current guidelines for patients experiencing a concussion or mild traumatic brain injury (mTBI) often focus on conservative care and observation. However, mTBI may increase the risk of severe novel psychiatric disorders (NPDs) within 180 days, long-term management should include evaluation in patient populations. Retrospective cohort analysis was conducted using 8 years Nationwide Readmission Database. All individuals who were admitted readmitted days queried. This then subdivided based age,...