- Proteins in Food Systems
- Protein Interaction Studies and Fluorescence Analysis
- Surfactants and Colloidal Systems
- Lipid Membrane Structure and Behavior
- Blood properties and coagulation
- Enzyme Production and Characterization
- Enzyme Catalysis and Immobilization
- Biochemical and Structural Characterization
- Analytical Chemistry and Chromatography
- DNA and Nucleic Acid Chemistry
- Bacteriophages and microbial interactions
- Erythrocyte Function and Pathophysiology
- Protein Structure and Dynamics
- Protein Hydrolysis and Bioactive Peptides
- Protein purification and stability
- Pineapple and bromelain studies
- Seaweed-derived Bioactive Compounds
- Advanced Polymer Synthesis and Characterization
- Carbon Nanotubes in Composites
- thermodynamics and calorimetric analyses
- Advanced Cellulose Research Studies
- Electrostatics and Colloid Interactions
- Transgenic Plants and Applications
- Polysaccharides Composition and Applications
- Antimicrobial Peptides and Activities
Kazan Institute of Biochemistry and Biophysics
2015-2024
A.E. Arbuzov Institute of Organic and Physical Chemistry
2023-2024
Kazan Federal University
2014-2020
Russian Academy of Sciences
2000-2015
Hydrogels have the ability to retain large amounts of water within their three-dimensional polymer matrices. These attractive materials are used in medicine and food industry; they can serve as basis for structured products, additives, various ingredients. Gelatin is one widely biopolymers create hydrogels that exhibit biocompatibility tunable rheological properties. In this study, we offer a comparative analysis properties gelatin-based (C = 6.67%), including mammalian gelatins from bovine...
Self-organization of hydroxyethylated gemini surfactants with different spacer fragments 16-s-16(OH) (s = 4, 6, 10, and 12) was studied in single solutions binary surfactant-oligonucleotide systems. Despite the fact that aggregation activity solubilization capacity aggregates decrease an increase length, longer demonstrate superior binding toward oligonucleotide as compared to head surfactant analogs shorter spacers. The detailed study testified spacers are characterized by a looser packing...
This work aims to synthesize graft copolymers of chitosan and N-vinylimidazole (VI) with different compositions be used as matrices for the immobilization cysteine proteases-bromelain, ficin, papain. The are synthesized by free radical solution copolymerization a potassium persulfate-sodium metabisulfite blend initiator. have relatively high frequency grafting yields. All water-soluble, their solutions characterized DLS laser Doppler microelectrophoresis. self-assembled in aqueous solutions,...
The deposition of proteins in the form insoluble amyloid fibril aggregates is linked to a range diseases. supramolecular architecture such deposits governed by propagation β-strands direction protofilament growth. In present study, we analyze structural changes hen egg-white lysozyme fibrils upon their interactions with polysaccharides, using AFM and FTIR spectroscopy. Linear anionic as κ-carrageenan sodium alginate, are shown be capable disaggregate protofilaments eventual protein...
This study investigates the features of interactions between cysteine proteases (bromelain, ficin, and papain) a graft copolymer carboxymethyl cellulose sodium salt with N-vinylimidazole. The objective is to understand influence this on proteolytic activity stability enzymes. enzymes were immobilized through complexation carrier. interaction mechanism was examined using Fourier-transform infrared spectroscopy flexible molecular docking simulations. findings reveal that interact functional...
Abstract β‐Lactoglobulin (β‐LG) is a lipocalin, which the major whey protein of cow's milk and other mammals. However, it absent from human milk. The biological function β‐LG not clear, but its potential role in carrying fatty acids through digestive tract has been suggested. found complexes with lipids such as butyric oleic high affinity for wide variety compounds. Serotonin (5‐hydroxytryptamine, 5‐HT), an important compound animals plants, various functions, including regulation mood,...
Two diterpenoid surfactants with ammonium head groups and bromide (S1) or tosylate (S2) counterions have been synthesized. Exploration of these biomimetic species made it possible to demonstrate that even minor structural changes beyond their chemical nature may dramatically affect solution behavior. While aggregation thresholds differ inconsiderably, morphological behavior affinity lipid bilayer are strongly dependent on the counterion nature. Compound S2 demonstrates properties typical...
Enzyme immobilization on various carriers represents an effective approach to improve their stability, reusability, and even change catalytic properties. Here, we show the mechanism of interaction cysteine protease bromelain with water-soluble derivatives chitosan-carboxymethylchitosan,
The present work is devoted to research on the interaction between carboxymethyl cellulose sodium salt and its derivatives (graft copolymer of N,N-dimethyl aminoethyl methacrylate) with cysteine protease (ficin). was studied by FTIR flexible molecular docking, which have shown conjugates' formation both matrices. proteolytic activity assay performed azocasein demonstrated that specific activities all immobilized ficin samples are higher in comparison those native enzyme. This due modulation...