- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cerebrovascular and Carotid Artery Diseases
- Angiogenesis and VEGF in Cancer
- Cardiovascular Health and Disease Prevention
- Cardiovascular Disease and Adiposity
- Atherosclerosis and Cardiovascular Diseases
- Atrial Fibrillation Management and Outcomes
- Cardiac Fibrosis and Remodeling
- Cardiovascular Function and Risk Factors
- Antiplatelet Therapy and Cardiovascular Diseases
- Lipoproteins and Cardiovascular Health
- Inflammatory Biomarkers in Disease Prognosis
- Nitric Oxide and Endothelin Effects
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Protease and Inhibitor Mechanisms
- Acute Myocardial Infarction Research
- Acute Ischemic Stroke Management
- Peptidase Inhibition and Analysis
- Medical Imaging Techniques and Applications
- Blood Pressure and Hypertension Studies
- Biomarkers in Disease Mechanisms
- MicroRNA in disease regulation
- Pulmonary Hypertension Research and Treatments
Second Hospital of Nanchang
2021
Brigham and Women's Hospital
2014-2021
National and Kapodistrian University of Athens
2011-2020
Harvard University
2014-2019
University General Hospital Attikon
2019
Universitat de Barcelona
2019
Massachusetts Institute of Technology
2014-2016
NewYork–Presbyterian Hospital
2016
Hygeia Hospital
1997-2016
New York Hospital Queens
2016
Despite the exposure of entire vasculature to atherogenic effects systemic risk factors, atherosclerotic plaques preferentially develop at sites with disturbed flow. This study aimed exploring in vivo relationship between local endothelial shear stress (ESS) and coronary plaque characteristics humans using computational fluid dynamics frequency-domain optical coherence tomography.Three-dimensional artery reconstruction was performed 21 patients (24 arteries) presenting acute syndrome...
Background: Right ventricular (RV) systolic function has been recognized as a prognostic factor in endstage heart failure (HF) patients and the present study we evaluated effect of this dysfunction on prognosis with newly-diagnosed HF. Methods Results: We enrolled 180 consecutive newly diagnosed HF (ischemic or dilated cardiomyopathy). Echocardiographic evaluation was performed to assess biventricular function. Pulse-wave tissue Doppler imaging (TDI) readings were obtained from lateral...
Cardioembolism is a postulated mechanism of embolic stroke undetermined source (ESUS). We investigated endothelial glycocalyx, aortic elastic properties, oxidative stress, and their association with left atrial (LA) function in ESUS healthy individuals. In 90 patients (age 50.4 ± 13.2) controls similar risk factors, we measured: (1) perfused boundary region (PBR) the sublingual arterial microvessels (range 5-25 µm), marker inversely related glycocalyx thickness, (2) pulse wave velocity...
Objective The age-dependent performance of electrocardiographic (ECG) criteria was examined for left ventricular hypertrophy (LVH) prediction. Methods During 2009, 570 middle-aged (54 ± 7 years, 45% men) and 507 elderly (75 6 inhabitants the Ikaria Island were studied. Seven ECG calculated (Sokolow–Lyon voltage product, sex-specific Cornell Gubner–Ungerleider voltage, Lewis Framingham), whereas LVH defined as mass indexed body surface area (BSA) at least 125 g/m2 in men 110 women or...
Background In‐stent hyperplasia ( ISH ) may develop in regions of low endothelial shear stress ESS ), but the relationship between magnitude , extent ISH, and subsequent clinical events has not been investigated. Methods Results We assessed association poststent with neointimal outcomes patients treated percutaneous coronary interventions PCI ). Three‐dimensional reconstruction was performed 374 post‐ at baseline 6 to 10 months follow‐up as part PREDICTION Study. Each vessel divided into...