- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac Structural Anomalies and Repair
- Neurological disorders and treatments
- Cultural Studies and Interdisciplinary Research
- Mechanical Circulatory Support Devices
- Cardiovascular Function and Risk Factors
- Shakespeare, Adaptation, and Literary Criticism
- Joseph Conrad and Literature
- Cardiac Valve Diseases and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Cardiomyopathy and Myosin Studies
- Political Systems and Governance
- Global Peace and Security Dynamics
- Cardiac tumors and thrombi
- Medical History and Research
- Radioactive contamination and transfer
- Global Maritime and Colonial Histories
- Heart Failure Treatment and Management
- Bone Tissue Engineering Materials
- French Historical and Cultural Studies
Duke University Hospital
2013-2025
Duke Medical Center
2015-2024
Duke University
2011-2024
Clinical Research Institute
2009-2022
Unifor
2022
Magyar Agrár- és Élettudományi Egyetem
2022
Széchenyi István University
2022
Baylor University
2020
Eurostat
2019
University of the West Indies
2013
ABSTRACT Background The majority of data on left bundle branch area pacing (LBBAP) are a lumenless lead. Data the safety and effectiveness stylet driven leads comparatively lacking. Methods We retrospectively analyzed 265 patients who underwent attempted LBBAP with an 7842 (Boston Scientific, Marlborough, MA) lead in Duke University Health System between 1/1/2020 9/1/2023. Outcomes interest included post‐operative helix extension (≥2 rotations beyond tip), complications, parameters. A nested...
We conducted this pilot randomized clinical trial to determine the feasibility of a large aimed at testing whether early use catheter ablation ventricular tachycardia (VT) is superior antiarrhythmic medications reducing mortality.Patients were enrolled 4 sites if they had ischemic heart disease, an implantable cardioverter defibrillator (ICD), and received ≥1 ICD shock or ≥3 antitachycardia pacing therapies for VT. Patients 2 arms: (1) medication (n = 14) (2) 13); patients followed 3 6...
Device repositioning during Micra leadless pacemaker implantation may be required to achieve optimal pacing thresholds.The purpose of this study was describe the natural history acute elevated vs traditional transvenous lead thresholds.Micra VVI patients with threshold data (at 0.24 ms) at implant (n = 711) were compared Capture de novo leads 0.4 ms 538). In both cohorts, high thresholds defined as >1.0 V and very >1.5 V. Change in (0-6 months) (1.0 ≤1.5 V) or (>1.5 using Wilcoxon...
Cardiac implanted electronic device (CIED) pocket and systemic infection remain common complications with traditional CIEDs are associated high morbidity mortality. Leadless pacemakers may be an attractive pacing alternative for many patients following complete hardware removal a CIED by eliminating surgical pocket-related as well lower risk of recurrent complications.To describe use outcomes leadless pacemaker implantation extraction system due to infection.Patient characteristics...
Abstract Introduction Peak frequency (PF) mapping is a novel method that may identify critical portions of myocardial substrate supporting reentry. The aim this study was to describe and evaluate PF combined with omnipolar voltage in the identification isthmuses left atrial (LA) atypical flutters. Methods Results LA maps were generated flutter using Advisor HD‐Grid catheter (Abbott) EnSite Precision Mapping System 12 patients. Normal defined as ≥0.5 mV, low‐voltage 0.1−0.5 scar <0.1 mV....
AimsPre-implant assessment of longitudinal mechanical dyssynchrony using cross-correlation analysis (XCA) was tested for association with long-term survival and compared other tissue Doppler imaging (TDI)-derived indices.
BackgroundDiabetes mellitus (DM) is an independent risk factor for atrial fibrillation (AF). Few studies have compared clinical outcomes after catheter ablation between patients with and those without DM.ObjectiveThe purpose of this study was to compare AF in DM.MethodsWe performed a retrospective analysis 351 consecutive who underwent first-time ablation. Clinical included freedom from recurrent arrhythmia, symptom burden (Mayo Symptom Inventory score), cardiovascular all-cause...
The Medtronic Attain Stability Quad lead is a quadripolar left ventricular (LV) with an active fixation helix assembly designed to fixate the within coronary sinus and pace nonapical regions of LV. primary objective this study was determine safety effectiveness novel LV lead.Patients standard indications for cardiac resynchronization therapy (CRT) were enrolled. All patients followed at 3 6 months post-implant every thereafter until closure. Pacing capture thresholds (PCTs) measured implant...
Patients with severe mental illness (SMI) including schizophrenia, bipolar disorder, and depression have earlier onset of cardiovascular risk factors, predisposing to worse future heart failure (HF) compared the general population. We investigated associations between presence/absence SMI long-term HF outcomes.We identified patients without in Duke University Health System from 2002 2017. Using multivariable Cox regression, we examined primary outcome all-cause mortality. Secondary outcomes...
Cardiac amyloidosis is a progressive infiltrative disease involving deposition of amyloid fibrils in the myocardium and cardiac conduction system that frequently manifests with heart failure (HF) arrhythmias, most atrial fibrillation (AF), flutter (AFL), tachycardia (AT).We performed an observational retrospective study patients diagnosis who underwent catheter ablation at our institution between January 1, 2011 December 2018. Patient demographics, procedural characteristics, outcomes were...
Background Proper positioning of the left ventricular (LV) lead improves clinical outcomes and survival in patients receiving cardiac resynchronization therapy (CRT). Techniques LV insertion using contrast injection a telescoping system delivery catheters to support advancement into target branch may allow more efficient, targeted placement. We sought evaluate impact an implant approach telescoping‐support (group TS) on success rate, location, procedural time compared standard over‐the‐wire...
Atrioventricular (AV)-synchronous single-chamber leadless pacing using a mechanical atrial sensing algorithm produced high AV synchrony in clinical trials, but practice experience with these devices has not yet been described.To describe outcomes and programming changes AV-synchronous pacemakers practice.Consecutive patients without persistent fibrillation who received an pacemaker completed follow-up between February 2020 April 2021 were included. We evaluated tracking index (atrial sense...
Abstract Aims Patient selection is a key component of securing optimal patient outcomes with leadless pacing. We sought to describe and compare characteristics Micra patients without primary pacing indication associated atrial fibrillation (AF) in the IDE trial. Methods results The outcome (risk cardiac failure, pacemaker syndrome, or syncope related system procedure) was compared between successfully implanted from trial AF history (AF group) those (non-AF group). Among 720 Micra, 228...