A5101893402- Peroxisome Proliferator-Activated Receptors
- Natural product bioactivities and synthesis
- Gut microbiota and health
- Parkinson's Disease Mechanisms and Treatments
- Angiogenesis and VEGF in Cancer
- Clostridium difficile and Clostridium perfringens research
- Lipid metabolism and disorders
- Phytochemistry and Biological Activities
- Diet and metabolism studies
- Immunotherapy and Immune Responses
- Genetics and Neurodevelopmental Disorders
- High-Temperature Coating Behaviors
- Pharmacovigilance and Adverse Drug Reactions
- Toxin Mechanisms and Immunotoxins
- Cardiovascular Health and Disease Prevention
- Prostate Cancer Treatment and Research
- Lipid metabolism and biosynthesis
- Yeasts and Rust Fungi Studies
- Olfactory and Sensory Function Studies
- Bone Metabolism and Diseases
- Cholesterol and Lipid Metabolism
- Neurological disorders and treatments
- Genetic Neurodegenerative Diseases
- Phytochemistry and Bioactive Compounds
- High Entropy Alloys Studies
Guangzhou University of Chinese Medicine
2020-2024
Central South University
2020-2023
Xiangya Hospital Central South University
2020-2023
Henan University Huaihe Hospital and Huaihe Clinical Institute
2023
China Pharmaceutical University
2021
Shougang (China)
2020
Zoucheng People's Hospital
2009-2014
Background and Objective: Olfactory dysfunction (hyposmia) is an important non-motor symptom of Parkinson’s disease (PD). To investigate the potential prognostic value hyposmia as a marker for progression, we prospectively assessed clinical manifestations longitudinal changes hyposmic PD patients normosmic ones. Methods function was evaluated with Sniffin’ Sticks in at baseline. One hundred five 59 were enrolled followed up 2 years. They subsequently baseline during follow-up periods...
Complete lecithin:cholesterol acyltransferase (LCAT) deficiency is associated with fasting hypertriglyceridemia (HTG). We recently reported that, in ldlr −/− ×lcat mice, HTG hepatic triglyceride overproduction association an upregulation of the srebp1 gene and altered expression its target genes lipogenesis gluconeogenesis. further investigated role polyunsaturated fatty acid (PUFA) metabolism modulation lipid phenotypes. In using +/+ littermate as controls, level cholesterol esters (CE)...
ABSTRACT Fecal matter is recognized as both a reservoir and transmission source for various antimicrobial resistance genes (AMRGs). However, the transcriptional activity of AMRGs in swine feces not well understood. In addition, effect fecal microbiota transplantation (FMT) on excretion has rarely been reported. Our study explored diversity, abundance, activity, bacterial hosts Tibetan Duroc pig using metagenomic metatranscriptomic sequencing technologies. We discovered significantly higher...
Objective There is controversial evidence that FMR1 premutation or “gray zone” (GZ) allele (small CGG expansion, 45–54 repeats) was associated with Parkinson’s disease (PD). We aimed to explore further the association between repeat expansions and PD in a large sample of Chinese origin. Methods included cohort 2,362 patients 1,072 controls from Disease Movement Disorders Multicenter Database Collaborative Network China (PD-MDCNC) this study conducted repeat-primed polymerase chain reaction...
Prostate cancer is a common male urinary system globally with poor prognosis. Our research aims to explore the role of spirit-quieting Traditional Chinese Medicine in treatment prostate metastasis patients depression and its underlying mechanism. Currently, based on theory enzyme-activated bone degradation, we consider that MAOA mediates vicious cycle among tumor cells, osteoblasts, osteoclasts stromal cells facilitating PCa visceral organs, which was effectively reduced by TCM inhibition...
Objective To explore whether endothelial progenitor cells(EPCs)exerts therapeutic effects on rats with diabetic peripheral neuropathy(DPN). Methods Diabetes was induced by streptozotocin. Male SD were divided into normal control group(NC group), neuropathy group(DPN DPN+ saline group(DPN+ S and EPCs group. Sciatic nerve motor conduction velocity(MNCV)was measured a electromyography trigger potentiometer instrument. Pathological changes observed under optical microscope electron...
Objective To explore the mechanism of bone marrow-derived endothelial progenitor cells(EPCs)in treatment peripheral neuropathy diabetic rats. Methods Rats with neuropathy(DPN)were induced by streptozotocin(60 mg/kg). Male SD rats were divided into normal control group(NC group), DPN group, DPN+ saline group(DPN+ S and EPCs group. Sciatic nerve motor conduction velocity(MNCV)was measured. The expressions NF-κB myelin basic protein(MBP)in sciatic detected...
Objective To observe the effect of Xiaochaihu Decoction on cytokines and MAO in model rats with experimental autoimmune prostatitis (EAP) to provide an basis for use Chinese herbal prescriptions treatment chronic prostatitis. Methods Thirty male Wistar were randomly divided into blank Group, group (Xiaochaihu Decoction). Except group, groups injected subcutaneously multiple points days 0 30 prostatic protein extractive solution (60 mg/mL), intraperitoneally diph-theria-pertussis tetanus...