A5100404750- Bladder and Urothelial Cancer Treatments
- Ferroptosis and cancer prognosis
- Urinary Bladder and Prostate Research
- Cancer Immunotherapy and Biomarkers
- RNA modifications and cancer
- Bone Metabolism and Diseases
- Healthcare and Venom Research
- Epigenetics and DNA Methylation
- Urinary and Genital Oncology Studies
- Orthopedic Infections and Treatments
- Orthopaedic implants and arthroplasty
- Facial Trauma and Fracture Management
- Immune Cell Function and Interaction
- Dental Radiography and Imaging
- Bone health and treatments
- Cancer Mechanisms and Therapy
- Advanced Fluorescence Microscopy Techniques
- Testicular diseases and treatments
- Immunotherapy and Immune Responses
- Prostate Cancer Treatment and Research
- Cancer Research and Treatments
- Sexual function and dysfunction studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Urinary Tract Infections Management
- Advanced Proteomics Techniques and Applications
Shougang (China)
2020-2023
Liaoning Cancer Hospital & Institute
2023
Lanzhou University
2018
Lanzhou University Second Hospital
2018
The Fourth People's Hospital of Ningxia Hui Autonomous Region
2013
Xian Yang Central Hospital
2013
First Affiliated Hospital of Xi'an Jiaotong University
2011
Background SMARCA4, the essential ATPase subunit of SWI/SNF chromatin remodeling complex, regulates transcription through control structure and is increasingly thought to play significant roles in human cancers. This study aims explore potential role SMARCA4 with a view providing insights on pathologic mechanisms implicated here. Methods The different tumors were explored based Cancer Genome Atlas (TCGA), Genotype-tissue expression (GTEx), Tumor Immune Estimation Resource (TIMER), Gene Set...
BackgroundAcquired resistance to targeted drugs is a major challenge in cancer. The drug-tolerant state has been proposed be an initial step towards acquisition of real drug-resistance. Drug tolerant persister (DTP) cells are purported survive during treatment and stay dormant for several years. Single cell sequencing can provide comprehensive landscape gene expression DTP cells, which facilitate investigation heterogeneity drug identification new anticancer targets.MethodsThe genetic...
Abstract: Immune checkpoint inhibitors (ICIs) including anti-cytotoxic T-lymphocyte-associated protein 4 (anti-CTLA4) and anti-programmed death cell 1 (anti-PD1) have extended patient survival benefit revolutionized cancer treatment. As ICIs rely on immune regeneration to eliminate tumor cells, they can also lead an imbalance of reactions often called immune-related adverse events (irAEs). Rare irAEs such as ocular or cardiac toxicity vasculitis are seen in less than 1% patients receiving...
Urine biomarkers offer a non‑invasive method of detecting bladder cancer, monitoring disease progression and predicting recurrence therapeutic treatment efficacy. Tenascin‑C (TN‑C), as component the extracellular matrix, is vital in cancer. However, there little to report with regard urine TN‑C its correlation cancer grade, stage, prognosis. In present study, 66 samples voided from patients 42 volunteers were obtained. The concentration was determined using an ELISA assay. between tumor...
Objective: To observe the therapeutic effect of mild moxibustion on preventing and treating bladder spasms after transurethral resection prostate. Method: The control group patients were given routine perioperative care, while experimental Taixi, Zhongji, Qihai, Shenque points in addition to care. Result: frequency spasms, degree pain, significantly better than those group, differences statistically significant (P<0.05). Conclusion: Mild is safe reliable
Objective: To explore the clinical effect and safety of modified Chailing paste on improving postoperative lower urinary tract symptoms (LUTS) bladder neck contracture in pa-tients with small-volume prostatic hyperplasia (SBPH) complicated chronic prostatitis after transurethral resection prostate (TURP). Methods: A total 145 patients SBPH were enrolled a randomized double-blind placebo-controlled study randomly divided into three groups. Group (49 patients) underwent simple TURP, B (48 TURP...
Prostate cancer is a common male urinary system globally with poor prognosis. Our research aims to explore the role of spirit-quieting Traditional Chinese Medicine in treatment prostate metastasis patients depression and its underlying mechanism. Currently, based on theory enzyme-activated bone degradation, we consider that MAOA mediates vicious cycle among tumor cells, osteoblasts, osteoclasts stromal cells facilitating PCa visceral organs, which was effectively reduced by TCM inhibition...
Xiao-Chai-Hu-Tang (XCHT), a representative of previous edition Formulas Traditional Chinese Medicine and harmonizing formulas, has multiple pharmacological functions. However, variety side effects could be caused by misuse or abuse, ignoring the theory diagnosis treatment based on combination syndrome disease differentiation. Therefore, we conducted retrospective study to evaluate efficacy XCHT, depending upon individual patient’s condition. Among 98 patients treated with most syndromes...
Objective To observe the effect of Xiaochaihu Decoction on cytokines and MAO in model rats with experimental autoimmune prostatitis (EAP) to provide an basis for use Chinese herbal prescriptions treatment chronic prostatitis. Methods Thirty male Wistar were randomly divided into blank Group, group (Xiaochaihu Decoction). Except group, groups injected subcutaneously multiple points days 0 30 prostatic protein extractive solution (60 mg/mL), intraperitoneally diph-theria-pertussis tetanus...