A5100429664- Angiogenesis and VEGF in Cancer
- Medical Image Segmentation Techniques
- Cell Image Analysis Techniques
- Probiotics and Fermented Foods
- Advanced biosensing and bioanalysis techniques
- Electrochemical sensors and biosensors
- Gut microbiota and health
- AI in cancer detection
- Water Systems and Optimization
- Cancer-related molecular mechanisms research
- Proteoglycans and glycosaminoglycans research
- Nanopore and Nanochannel Transport Studies
- Legume Nitrogen Fixing Symbiosis
- Genetic Associations and Epidemiology
- Digestive system and related health
- Electrochemical Analysis and Applications
- Lipid metabolism and disorders
- 3D Printing in Biomedical Research
- Plant Toxicity and Pharmacological Properties
- Composite Material Mechanics
- Advanced Mathematical Modeling in Engineering
- Artificial Immune Systems Applications
- Optical Coherence Tomography Applications
- Photosynthetic Processes and Mechanisms
- Dermatology and Skin Diseases
University of Chinese Academy of Sciences
2024-2025
BGI Group (China)
2024-2025
BGI Research
2024-2025
Yangzhou University
2024
Zhengzhou University
2023
Shenyang Medical College
2023
Ningbo University
2023
Tongji University
2020
Tongji Hospital
2020
The First People's Hospital of Changzhou
2020
Introduction Atopic dermatitis (AD) is an allergic disease with extreme itching that bothers patients. However, diagnosing AD depends on clinicians’ subjective judgment, which may be missed or misdiagnosed sometimes. Methods This paper establishes a medical prediction model for the first time basis of enhanced particle swarm optimization (SRWPSO) algorithm and fuzzy K-nearest neighbor (FKNN), called bSRWPSO-FKNN, practiced dataset related to patients AD. In SRWPSO, Sobol sequence introduced...
Abstract The Illumina HiSeq platform has been a commonly used option for bacterial genome sequencing. Now the BGI DNA nanoball (DNB) nanoarrays may provide an alternative sequencing of genomes. To explore impact platforms on assembly, quality assessment, sequence alignment, functional annotation, mutation detection, and metagenome mapping, we compared assemblies based cultured species using 2000 BGISEQ-500 platforms. In addition, simulated reads were to evaluate insert size assembly. Genome...
Numerous studies have confirmed that gut microbiota is a key driver in the occurrence and progression of inflammatory bowel disease (IBD). Based on bacterial collection constructed our previous studies, we founded Bifidobacterium adolescentis AF91-08b2A has potential beneficial function. We designed cohort genomic animal experiments to further explore probiotic function its therapeutic effect IBD. The depletion B. individuals with IBD suggested significance for intestinal health. Genomic...
Illustration of the procedure for preparation a CFGO and SWCNTs-based electrochemical DNA biosensor.
Introduction Faecalibacterium is one of the most abundant bacteria in gut microbiota healthy adults, highly regarded as a next-generation probiotic. However, functions genomes from cultured strains and distribution different species populations may differ among sources. Methods We here performed an extensive analysis pan-genomes, functions, safety evaluation 136 collected 10 countries. Results The are clustered into 11 clusters, with only five them were characterized validly nomenclated....
Natural gas distribution systems are inherently vulnerable to accidental or intentional intrusion. Such events lead financial losses and endanger the environmental public safety. Therefore, it is crucial adequately monitor systems. An important step toward this goal optimize placement of sensors in network. In paper, we propose three design objectives including time-to-detection (TTD), sensitivity, impact propagation (IP) implement five multi-objective optimization algorithms (greedy, greedy...
Abstract Transplantion of bone marrow-derived endothelial progenitor cells (EPCs) may be a novel treatment for deep venous thrombosis (DVT). The present study probed into the role microRNA (miR)-361-5p in EPCs and DVT recanalization. were isolated from male Sprague–Dawley (SD) rats identified using confocal microscopy flow cytometry. viability, migration tube formation examined MTT assay, wound-healing assay respectively. Target gene potential binding sites between miR-361-5p fibroblast...
Cell migration is a key feature for living organisms. Image analysis tools are useful in studying cell three-dimensional (3-D) vitro environments. We consider angiogenic vessels formed 3-D microfluidic devices (MFDs) and develop an image system to extract behaviors from experimental phase-contrast microscopy sequences. The proposed initializes tracks with the end-point confocal nuclei coordinates. apply convolutional neural networks detect candidates combine backward Kalman filtering...
Cell migration is a fundamental process for the development and maintenance of all multicellular organisms. Accurate cell tracking may lead to better interpretations long-term behaviours. This paper describes an automated system track multiple cells from experimental phase contrast images, which includes image registration, lumen segmentation, candidate detection, hypothesis Kalman filtering. We incorporate biological knowledge associate new observations existing tracks. apply our...
ABSTRACT Introduction Sepsis can cause decreased diaphragmatic contractility. Intracellular calcium as a second messenger is central to However, changes in intracellular concentration ([Ca 2+ ]) and the distribution co‐localization of relevant channels [dihydropyridine receptors, (DHPRα1s) ryanodine receptors (RyR1)] remain unclear during sepsis. In this study we investigated effect changed [Ca ] expression DHPRα1s RyR1 on diaphragm function Methods We measured contractility isolated muscle...
Angiogenesis, the growth of new blood vessels from pre-existing vessels, is a critical step in cancer invasion. Better understanding angiogenic mechanisms required to develop effective antiangiogenic therapies for treatment. We culture 3D microfluidic devices under different Sphingosin-1-phosphate (S1P) conditions and an automated vessel formation tracking system (AVFTS) track extract quantitative information experimental time-lapse phase contrast images. The proposed AVFTS first...
<abstract><p>This paper derived the homogenization of heat equation with random convolutional potential. By Tartar's method oscillating test function, solution potential was shown to converge in distribution effective determined potential.</p></abstract>
<h3>Background</h3> Ulcerative colitis (UC) is a chronic immune-mediated disorder primarily characterized by gastrointestinal tract inflammation. Probiotics are an adjunct to traditional drug therapy for UC. In this study, Bifidobacterium adolescentis AF91-08b2A was isolated and screened, the beneficial effect of B. on mice induced sodium dextran sulfate (DSS) evaluated. Our data show that alleviates IBD symptoms protecting against intestinal barrier damage modulating immune response....
Abstract Aims To investigate the association of methylation risk score (MRS) and its interactions with environmental factors type 2 diabetes mellitus (T2DM) risk. Methods We conducted a nested case–control study 241 onset cases matched controls. Conditional logistic regression models were employed to identify CpG sites. Simple weighted MRSs constructed based on levels ATP‐binding cassette G1 gene, fat mass obesity associated potassium voltage‐gated channel member 1 thioredoxin‐interacting...
Skin whiteness is an attribute that frequently used to describe skin colour.This study investigated the relationship between perceived and associated physical measurements.A psychophysical experiment was conducted with 40 participants (20 Chinese 20 Caucasian).Images of eighty real human faces, from Leeds-Liverpool colour database (LLSD), were in experiment.The correlation experimental results CIELAB colorimetric scales showed has a relatively strong L* b* values, less a*.Two related...