A5100342850- Stoma care and complications
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Cancer survivorship and care
- Hernia repair and management
- Nutrition and Health in Aging
- Hip disorders and treatments
- Orthopaedic implants and arthroplasty
- Pelvic and Acetabular Injuries
- Atrial Fibrillation Management and Outcomes
- Total Knee Arthroplasty Outcomes
- Helicobacter pylori-related gastroenterology studies
- Cervical Cancer and HPV Research
- Epigenetics and DNA Methylation
- Spine and Intervertebral Disc Pathology
- Systemic Lupus Erythematosus Research
- Cancer Treatment and Pharmacology
- Spinal Fractures and Fixation Techniques
- Bladder and Urothelial Cancer Treatments
- Cancer-related molecular mechanisms research
- Thyroid Cancer Diagnosis and Treatment
- Surgical site infection prevention
- Antiplatelet Therapy and Cardiovascular Diseases
- Enhanced Recovery After Surgery
- Cardiac electrophysiology and arrhythmias
Harbin Medical University
2023-2025
Second Affiliated Hospital of Harbin Medical University
2025
First Affiliated Hospital of Shantou University Medical College
2019-2024
Northeastern University
2024
Sun Yat-sen University
2012-2024
Beijing Sport University
2023-2024
Union Hospital
2024
Southeast University
2022-2024
Shantou University
2019-2024
Nanjing University of Chinese Medicine
2023-2024
Abstract Antiphospholipid syndrome (APS) is a heterogeneous autoimmune disease with persistent antiphospholipid antibodies. This study aimed to identify unrecognized APS subgroups from multicenter cohorts ( n = 760, training: 415; validation: 345). Patients are stratified through unsupervised K‐means clustering analysis. Prognostic outcomes evaluated using Kaplan‐Meier survival analyses. Proteomic analysis conducted on primary patients 36) and healthy controls 12). Key molecule insulin‐like...
Surgical site infection (SSI) is a costly postoperative complication with decrease in the quality of life. We aimed to probe predictive role peripheral blood inflammation markers for SSI following mesh repair groin hernia (GH).This retrospective study assessed data 1177 patients undergoing elective GH (open/laparoscopy) absence antibiotic prophylaxis. The relation between demographics, surgical factors, pre-surgical laboratory results and occurrence were investigated by univariate...
To evaluate the diagnostic value of combining neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte (PLR) or lymphocyte-monocyte (LMR) with carcinoembryonic antigen (CEA) in patients colorectal cancer (CRC).The performance inflammatory makers and CEA was evaluated cohort 1 (664 CRC, 336 polyps 664 healthy controls) validated 2 (87 CRC 87 by using receiver operating characteristic curve analysis.In 1, NLR, PLR levels were significantly higher, while LMR markedly lower than controls. The...
Background: Chromobox (CBX) proteins are essential components of polycomb group and perform functions in bladder cancer (BLCA). However, research on CBX is still limited, the function CBXs BLCA has not been well illustrated. Methods Results: We analyzed expression family members patients from The Cancer Genome Atlas database. By Cox regression analysis survival analysis, CBX6 CBX7 were identified as potential prognostic factors. Subsequently, we genes associated with CBX6/7 performed...
Abstract Background Significant concomitants of the sick role maladaptation in colorectal cancer (CRC) patients include inappropriate cognitions, emotional states, and overt conducts associated to disease. This protocol was developed implement evaluate effects a self-led, virtual reality-based cognitive behavioral therapy (VR-CBT) on adaptation among working-age CRC patients. Methods is an assessor-blinded, randomized controlled trail that adheres SPIRIT 2013 Statement guidelines. A total 60...
Abstract Background We aimed to investigate the impact of sociodemographic and clinical characteristics on health-related quality life (HRQoL) in disease-free survivors after radical surgery for rectal cancer a Chinese mainland population. Methods performed cross-sectional survey from August 2002 February 2011 by use European Organization Research Treatment Cancer (EORTC) QLQ-C30 QLQ-CR38 questionnaires 438 patients who underwent curative cancer. Patients were followed up minimum 6 months,...
People living with HIV (PLWH) have increased risks of non-communicable diseases, especially cardiovascular diseases. Current clinical management guidelines recommend regular risk screening, but the equation models are not specific for PLWH. Better tools needed to assess among PLWH accurately.We performed a prospective study determine performance automatic retinal image analysis in assessing coronary artery disease (CAD) We enrolled ≥1 factor. All participants had computerized tomography (CT)...
The adequacy of screw anchorage is a critical factor in achieving successful spinal fusion. This study aimed to use machine learning algorithms identify variables and predict pedicle loosening after degenerative lumbar fusion surgery. A total 552 patients who underwent primary transpedicular fixation for disease were included. LASSO method identified key features associated with loosening. Patient clinical characteristics, intraoperative variables, radiographic parameters collected used...
Abstract Recent research underscores the significance of nervous system in tumor progression. Nonetheless, understanding intricate roles nerves gastric tumorigenesis remains limited. Our study aims to elucidate nerve alterations, associated key genes, and signaling pathways during tumorigenesis. We enroll 257 patients with precancerous lesions (GPLs) from four national cohorts. Utilizing immunohistochemistry digital analysis, we quantified densities sympathetic parasympathetic nerves, as...
Two new secalonic acid derivatives, acids H and I (1 2), one known compound, D (3), were isolated from the marine-derived fungus Penicillum oxalicum.The planar structures relative configurations of compounds elucidated by analyses their 1D 2D NMR high-resolution mass spectrometric data.The absolute established comparison experimental calculated electronic circular dichroism spectra.The in vitro cytotoxic activities 1 2 evaluated against selected human cell lines.Cancer is leading causes...
High serum insulin-like growth factor binding protein-7 (IGFBP-7) has been found in several malignant tumors. Here, we aimed to assess the diagnostic potential of IGFBP7 patients with colorectal cancer (CRC).An enzyme-linked immunosorbent assay (ELISA) was performed detect level 115 CRC and 107 healthy controls, receiver operating characteristics (ROC) used evaluate accuracy diagnosis.The levels were significantly higher than those normal controls (P < 0.001). With optimized cutoff 2.050...
The diffuse sclerosing variant of papillary thyroid carcinoma (DSV-PTC) has ultrasound findings that are similar to Hashimoto's thyroiditis (HT), resulting in under-diagnosis. DSV-PTC combined with HT is also common, so early and accurate diagnosis using a variety diagnostic techniques, including FNAC, BRAFV600E mutation detection, elastography, critical.To assess the value fine-needle aspiration cytology (FNAC) detection combination elastography DSV-PTC.We performed retrospective analysis...
As one of the most prevalent genitourinary cancers, bladder cancer (BLCA) is associated with high morbidity and mortality. Currently, limited indicators are available for early detection diagnosis cancer, there a lack specific biomarkers evaluating prognosis BLCA patients. This study aims to identify critical genes that affect immunity improve new targets immunotherapy.Two GEO datasets were used screen differentially expressed (DEGs). The STRING database was construct protein-protein...
The aim of this study was to assess the effect Helicobactor pylori (H. pylori) infection and drug therapy on functional dyspepsia (FD) symptoms gastrointestinal eosinophil count. In study, 215 continuous FD patients fulfilling Rome Ⅲ criteria were enrolled. divided into a H. pylori-positive group pylori‑negative group. pylori‑eradicated pylori-uneradicated groups following pylori-eradication treatment, randomly esomeprazole teprenone treatment groups. symptom scores significantly lower...
This study aimed at establishing a new model to predict malignant thyroid nodules using machine learning algorithms.A retrospective was performed on 274 patients with who underwent fine-needle aspiration (FNA) cytology or surgery from October 2018 2020 in Xianyang Central Hospital. The least absolute shrinkage and selection operator (lasso) regression analysis logistic were applied screen identified variables. Six algorithms, including Decision Tree (DT), Extreme Gradient Boosting (XGBoost),...
Objective: Colorectal cancer is one of the most important malignant in world with high incidence and mortality. Some studies have found that expression low serum L1 cell adhesion molecule associated poor prognosis some malignancies. It suggested a candidate marker for certain tumors. However, relationship between colorectal cancer, especially about diagnostic value, rarely reported. Therefore, this study aimed to evaluate potential patients cancer. Methods: Enzyme-linked immunosorbent assay...
Gastrectomy is a technically demanding procedure for gastric cancer patients that associated with different degrees of postoperative complications (POCs). Perioperative traditional Chinese medicine (TCM) nursing intervention presents benefits improving the survival cancer. However, effects TCM on POCs and prognosis following surgery are far from clear. In present study, POCs, physical capacity, metal status, long-term recurrence were investigated in after gastrectomy. total, 1,032 included...
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