A5005825203- Acute Ischemic Stroke Management
- Bariatric Surgery and Outcomes
- Peripheral Neuropathies and Disorders
- Cerebrovascular and Carotid Artery Diseases
- Myasthenia Gravis and Thymoma
- Cardiovascular Health and Risk Factors
- Stroke Rehabilitation and Recovery
- Infective Endocarditis Diagnosis and Management
- Amino Acid Enzymes and Metabolism
- Venous Thromboembolism Diagnosis and Management
- Parkinson's Disease and Spinal Disorders
- Cerebral Venous Sinus Thrombosis
- Patient Satisfaction in Healthcare
- Vascular Procedures and Complications
- Peripheral Artery Disease Management
- Colorectal and Anal Carcinomas
- Vehicle emissions and performance
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Arrhythmias and Treatments
- Air Quality and Health Impacts
- Sleep and Wakefulness Research
- Genomics and Rare Diseases
- Metalloenzymes and iron-sulfur proteins
- Glycogen Storage Diseases and Myoclonus
- Healthcare Operations and Scheduling Optimization
Medical College of Wisconsin
2020-2024
Cleveland Clinic
2021-2024
The Neurological Institute
2024
Arcadia
2024
Nemocnice Břeclav
2024
<h3>Objective</h3> To evaluate whether eculizumab helps patients with anti–acetylcholine receptor–positive (AChR+) refractory generalized myasthenia gravis (gMG) achieve the Myasthenia Gravis Foundation of America (MGFA) post-intervention status minimal manifestations (MM), we assessed patients9 throughout REGAIN (Safety and Efficacy Eculizumab in AChR+ Refractory Generalized Gravis) its open-label extension. <h3>Methods</h3> Patients who completed randomized controlled trial continued into...
To evaluate the effect of eculizumab on perceived fatigue in patients with anti-acetylcholine receptor antibody-positive, refractory, generalized myasthenia gravis (MG) using Quality Life Neurological Disorders (Neuro-QOL) Fatigue subscale, and to correlations between improvements Neuro-QOL other clinical endpoints.Neuro-QOL Fatigue, MG Activities Daily Living (MG-ADL), Quantitative (QMG), 15-item (MG-QOL15) scales were administered during phase 3, randomized, placebo-controlled REGAIN study...
Introduction: Gastric bypass has not gained as much popularity in the Czech Republic technically simpler restrictive bariatric procedures, frequently with a fading long-term effect. The aim of presentation is to point out results after two types gastric bypasses. Method: Retrospective analysis prospectively collected data an initial set patients laparoscopic RYGB (Roux Y bypass) and OAGB/MGB (one anastomosis/mini performed at Breclav Hospital 2010−2013. Evaluation based on BAROS system,...
Background: Mobile stroke units (MSU) have reduced time to thrombolysis, improved outcomes in ischemic stroke, but their sustainability and external costs not been thoroughly evaluated. Fossil fuel combustion produces carbon dioxide (CO 2 ) air pollution, which contribute global climate crisis excess mortality. Aim: To estimate the mortality cost of MSU due increment CO pollution from burned by MSU. Methods: Fuel annual operation MSU, obtained through correspondence, was used obtain volume...
Evaluation of stroke etiology is an important aspect care affecting secondary prevention measures. Despite recent advances in diagnostic testing, determining the can remain a challenging task particularly for less common causes such as mitral annular calcification. This case will review benefit histopathologic clot evaluation after thrombectomy to identify uncommon embolic which may change management.
Intraluminal carotid thrombus (ILCT) is present in less than 2% of patients presenting with acute ischaemic stroke, and 75–81% ILCT cases are associated atherosclerosis [1,2]. We a rare case stroke on bare artery without plaque.
Introduction: Time-sensitive therapies can be delayed during weekends or off-hours. Regional systems of care require interfacility transfers from Primary Stroke Centers (PSC) to Comprehensive (CSC). Door-in door-out (DIDO) time, an emerging performance measure, is a modifiable factor in time thrombectomy. Off-hours presentation has been associated with longer Door-To-Needle (DTN) however its effect on DIDO unknown. Hypothesis: Presentation off-hours (before 8 AM, after 5 PM weekends)...
Introduction: We aimed to quantify and trend excess cerebrovascular deaths among middle-aged adults that could be attributed Black-white rural-urban disparity in the US. Methods: Annual age-adjusted mortality rates (AAMR) for ischemic stroke (IS), intracerebral hemorrhage (ICH), subarachnoid (SAH) middle aged (ages 35-64) were obtained from Centers Disease Control Prevention Wide-Ranging Online Data Epidemiological Research database 1999 2019. AAMR difference between African-Americans whites...
Background: We aimed to assess patient and family understanding of satisfaction with communication regarding acute stroke treatments intravenous thrombolysis (IVT) endovascular therapy (EVT). Methods: The study was conducted at a health system in the United States from November 2020 May 2021. A structured interview open-ended multiple choice questions over telephone or person within 72 hours patients surrogates whom were discussed. respondent self-reported rated on Likert scale. Responses...
Introduction: Despite observed overall decline cerebrovascular mortality in the United States over past 2 decades, geographic pockets of increasing among middle aged adults have been reported on county-level data; and factors driving this regional increase are poorly understood. Methods: We extracted rates (ICD tenth revision codes I60-I69) (age 35-64) from Centers for Disease Control Prevention Wide-Ranging Online Data Epidemiological Research database 1999 to 2018. Variations annual...