A5036665578- Systemic Lupus Erythematosus Research
- Rheumatoid Arthritis Research and Therapies
- Cancer-related molecular mechanisms research
- T-cell and B-cell Immunology
- Diabetes and associated disorders
- Inflammasome and immune disorders
- Cytokine Signaling Pathways and Interactions
- COVID-19 Clinical Research Studies
- MicroRNA in disease regulation
- Circular RNAs in diseases
- interferon and immune responses
- Immune Cell Function and Interaction
- Lymphoma Diagnosis and Treatment
- Digestive system and related health
- Bone Metabolism and Diseases
- Bone and Joint Diseases
- Bone health and osteoporosis research
- Data-Driven Disease Surveillance
- Mycobacterium research and diagnosis
- Spondyloarthritis Studies and Treatments
- Social Media in Health Education
- Adipokines, Inflammation, and Metabolic Diseases
- Chronic Lymphocytic Leukemia Research
- Genetic Associations and Epidemiology
- COVID-19 and healthcare impacts
Anhui Medical University
2016-2025
Second Hospital of Anhui Medical University
2023
Anhui Provincial Hospital
2020
Faculty of Public Health
2016
Periodontitis (PD) has been linked to arthritis in previous epidemiological observational studies; however, the results are inconclusive. It remains unclear whether association between PD and is causal. The purpose of this study was investigate causal with arthritis, including rheumatoid (RA) osteoarthritis (OA).We performed a two-sample bidirectional Mendelian randomization (MR) analysis using publicly released genome-wide studies (GWAS) statistics. inverse-variance weighted (IVW) method...
Circular RNAs (circRNAs) represent a class of non-coding that form covalently closed RNA circles with extensive expression and conservation in mammals. regulate gene through acting as competitive endogenous (ceRNAs) modulating transcription. Accumulating evidence supports the implication circRNAs variety human diseases, but studies circRNA role systemic lupus erythematosus (SLE) are lacking. The present study measured profiles T cells from patients SLE healthy controls microarray identified...
LncRNAs are increasingly recognized to play important roles in multiple autoimmune diseases. This study aimed evaluate the association of four lncRNAs (ANRIL, lnc-DC, MALAT1, ZFAS1) genes single nucleotide polymorphisms (SNPs) with susceptibility rheumatoid arthritis (RA) patients, as well their expression levels. Seventeen SNPs were genotyped a cohort 660 RA patients and 710 controls using improved ligase detection reaction (iMLDR). The expressions peripheral blood mononuclear cells (PBMCs)...
Pulmonary tuberculosis (TB) is an infectious disease caused by Mycobacterium affecting multiple tissues and organs. It one of the leading causes death a social in China. Increasing studies have revealed that state mental health support are associated with morbidity, mortality community transmission pulmonary TB patients. However, previous global control research strategy focused almost solely on biomedical aspects. Therefore, this study, we evaluated level depression explored potential...
Abstract TBX21 recode T-bet which is an important transcription factor that drives the Th1 immune response primarily by promoting expression of interferon-gamma ( IFNG ) gene. Recent studies have shown genetic variants in and are connected with risk systemic lupus erythematosus (SLE). The aim present study was to replicate these associations SLE Anhui Chinese population. Genotyping 3 (rs4794067 , rs2069705 rs2069718 performed. A total 3732 subjects were included final analysis. only...
Abstract To carry out an in-depth analysis of the scientific research on autoimmunity, we performed first bibliometric focusing publications in journals dedicated to autoimmunity (JDTA) indexed by science citation index during period 2004–2023. Using analysis, quantitatively and qualitatively analyzed country, institution, author, reference keywords information JDTA, so as understand quantity, publication pattern characteristics these publications. The co-occurrence networks, clustering map...
Objective Emerging evidence suggests an increased prevalence of coronavirus disease 2019 (COVID-19) in patients with systemic lupus erythematosus (SLE), the prototype autoimmune disease, compared to general population. However, conclusions were inconsistent, and causal relationship between COVID-19 SLE remains unknown. Methods In this study, we aimed evaluate bidirectional using Mendelian randomization (MR) analysis, including MR-Egger, weighted median, mode, inverse variance weighting (IVW)...