A5103100898- Gut microbiota and health
- Acute Ischemic Stroke Management
- Systemic Lupus Erythematosus Research
- Adipokines, Inflammation, and Metabolic Diseases
- Protein Degradation and Inhibitors
- Immune Cell Function and Interaction
- Colorectal Cancer Treatments and Studies
- Colorectal Cancer Surgical Treatments
- Cancer-related molecular mechanisms research
- Advancements in Semiconductor Devices and Circuit Design
- Fungal Biology and Applications
- RNA modifications and cancer
- Intracerebral and Subarachnoid Hemorrhage Research
- Traditional Chinese Medicine Analysis
- Esophageal and GI Pathology
- Pancreatitis Pathology and Treatment
- Vascular Anomalies and Treatments
- Systemic Sclerosis and Related Diseases
- Polysaccharides and Plant Cell Walls
- Diabetes and associated disorders
- Colorectal Cancer Screening and Detection
- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Metabolomics and Mass Spectrometry Studies
- Inflammasome and immune disorders
Huazhong University of Science and Technology
2017-2025
Guangxi Normal University
2025
Wuhan University of Science and Technology
2025
Guangzhou First People's Hospital
2020-2024
Affiliated Hospital of Youjiang Medical University for Nationalities
2024
Peking University Shenzhen Hospital
2024
Sichuan University
2022-2024
Hubei Cancer Hospital
2024
South China University of Technology
2020-2024
Guangzhou Medical University
2020-2024
Background: Although increasing evidences showed a correlation between cholecystectomy and the prevalence rate of colorectal cancer (CRC), shed light on gut microbiota in pathogenesis, only few studies focused microbial alterations after cholecystectomy, its sequent role carcinogenesis progression CRC has not been reported. Thus, we aimed to investigate bacterial tried clarify their clinical significance. Methods: 104 subjects were enrolled divided into post-cholecystectomy patients (PC, n =...
Long non-coding RNAs (LncRNAs) have been implicated as critical regulators of cancer tumorigenesis and progression. However, their functions molecular mechanisms in colorectal (CRC) still remain to be further elucidated.
<title>Abstract</title> Nature has a delicate system for catalysis due to optimization through evolution, which often displays unparalleled efficiency and selectivity. “learning from nature” is popular effective approach in designing new reactions catalysts when traditional strategies fail. Here, we proved that it can be highly rewarding consider nature’s repertoire of during the effort facilitate challenging heterolytic C–O bond cleavage methanol (MeOH) by studying its metabolism...
The current study aimed to test the effects of depressive symptoms and self-efficacy in relationship between activities daily living (ADLs) medication adherence using a serial mediation model. This cohort was conducted among 797 elderly with chronic diseases Hunan Province China. Their ADLs, adherence, self-efficacy, were assessed by Barthel Index (BI), Morisky Medication Adherence Scale (MMAS-8), Self-Efficacy for Appropriate Use (SEAMS), 20-item Center Epidemiologic Studies Depression...
Objective The objective of this study is to explore the clinicopathological characteristics gastric cancer and precancerous conditions in patients with primary lymphoma.Methods We analyzed 474 cases lymphoma, mainly DLBCL MALT, from three clinical centres retrospectively, compared parameters lymphoma complicated cancer, conditions, or no complications.Results A total 5.1% were diagnosed including metachronous adenocarcinoma (3.2%) synchronous (1.9%). Of 14.6% had atrophy (14.6%), intestinal...
Modern research has found that Ganoderma lucidum polysaccharides (GLP) and Polyporus umbellatus (PUP) mainly exhibit immunoregulation. However, the immune function of a polysaccharide composition consisting GLP PUP not been studied. In this study, we developed in ratio 3:1 (named GPP). The immunoregulation GPP was detected RAW264.7 macrophages. Then, acute oral toxicity effect on mice detected. results showed enhanced macrophage cells through improving phagocytic ability, nitric oxide (NO)...
Previous study have demonstrated that a compound composed of water-soluable Ganoderma lucidum polysaccharides (GLP) and Polyporus umbellatus (PUP) in ratio 3:1 named GPP enhances innate immune function mice through enhancing the macrophage cells activity natural killer (NK) cells. Here our research, we further investigated effect on diversity composition intestinal flora, explored its colitis model mice. The immunoregulatory verification experiments were conducted both normal DSS-induced...
Abstract Introduction Spatial changes of amine metabolites and histopathology the whole brain help to reveal mechanism traumatic injury (TBI) treatment. Methods A newly developed liquid microjunction surface sampling–tandem mass tag–ultra performance chromatography–mass spectrometry technique is applied profile in five regions after impact‐induced TBI at subacute stage. H&E, Nissl, immunofluorescence staining are performed spatially correlate microscopical metabolic alterations. Then,...
There is uncertainty surrounding the differences in outcomes after intracerebral haemorrhage (ICH) between men and women. This study aimed to investigate sex clinical characteristics, severity of Chinese ICH patients. The Nanjing First Hospital stroke registry was a hospital-based patients with 1-year prospective follow-up. From 2004 2008, total 651 consecutively recruited acute were enrolled. Primary outcome death or dependency defined as modified Rankin Scale score 3-6 at 12 months....
Thyroid nodule is a common thyroid disease, but the study of its pathology and pathogenesis still limited. As non-invasive diagnostic method, medical image examination great value to pathological correlation nodules. The purpose this was investigate expression eosinophils in between analyzed reports group patients with nodules examined by images performed corresponding imaging scans or examinations. data processed, including reconstruction, transmission other steps, generate that can be...
Shuganjieyu (SGJY) capsule is a classical formula widely used in Chinese clinical application. In this paper, an ultra-performance liquid chromatography coupled with electrospray ionization and ion trap mass spectrometry has been established to separate identify the chemical constituents of SGJY multiple rats. The chromatographic separation was performed on C 18 RRHD column (150 × 2.1 mm, 1.8 μm), while 0.1% formic acid–water acid–acetonitrile as mobile phase. Mass spectral data were...
Major depressive disorder (MDD) is a chronic mental characterized by mixed symptoms and complex pathogenesis. With long history of practical application, traditional Chinese medicine (TCM) offers many herbs for the treatment rehabilitation disease. In this study, we developed modified herbal formula using Panax ginseng, Angelica Sinensis, Polygala tenuifolia Willd, Ziziphi spinosae Semen (PAPZ), based on an ancient TCM prescription. The antidepressant effects PAPZ were investigated with...