A5112465367- Traumatic Brain Injury and Neurovascular Disturbances
- Tunneling and Rock Mechanics
- Cancer-related molecular mechanisms research
- Photonic and Optical Devices
- RNA modifications and cancer
- Drilling and Well Engineering
- Wound Healing and Treatments
- Metabolomics and Mass Spectrometry Studies
- Mitochondrial Function and Pathology
- Advancements in Battery Materials
- S100 Proteins and Annexins
- Cancer Immunotherapy and Biomarkers
- Intracranial Aneurysms: Treatment and Complications
- Advanced Battery Materials and Technologies
- Carbon and Quantum Dots Applications
- Intracerebral and Subarachnoid Hemorrhage Research
- Semiconductor Lasers and Optical Devices
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Alzheimer's disease research and treatments
- Chronic Kidney Disease and Diabetes
- Seaweed-derived Bioactive Compounds
- Silk-based biomaterials and applications
- Tissue Engineering and Regenerative Medicine
- Barrier Structure and Function Studies
Xiangya Hospital Central South University
2020-2025
Central South University
2018-2025
Peking University
2024-2025
Hubei Engineering University
2025
Nanyang Technological University
2024
National University of Singapore
2024
Shenzhen Institutes of Advanced Technology
2024
Chongqing University
2024
Harbin Engineering University
2024
Chinese Academy of Sciences
2024
Abstract Purpose Previous studies suggest an association between chronic kidney disease (CKD) and cognitive impairment. The purpose of this study was to explore the diverse stages CKD performance elderly American adults. Methods Data from National Health Nutrition Examination Survey (NHANES) 2011–2014 were used. Multivariate adjusted logistic regression, subgroup analysis, restricted cubic spline model used assess associations stage estimated glomerular filtration rate (eGFR) with...
Xuefu Zhuyu Decoction (XFZYD), a well-known traditional Chinese medicine prescription, has been widely used to treat traumatic brain injury (TBI). However, the underlying mechanisms involved in XFZYD therapy remain unclear.We explored new therapeutic targets of TBI by tsRNA-sequencing (tsRNA-seq) method.High-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) was assess quality XFZYD. Male Sprague-Dawley rats were randomly categorized into three groups: sham, TBI, and The...
Abstract Introduction Spatial changes of amine metabolites and histopathology the whole brain help to reveal mechanism traumatic injury (TBI) treatment. Methods A newly developed liquid microjunction surface sampling–tandem mass tag–ultra performance chromatography–mass spectrometry technique is applied profile in five regions after impact‐induced TBI at subacute stage. H&E, Nissl, immunofluorescence staining are performed spatially correlate microscopical metabolic alterations. Then,...
We report the critical thickness of a surface-functionalized coating for enhanced lithium storage.
Amygdalin is widely distributed in the plant kingdom. Oral delivery of amygdalin releases hydrogen cyanide upon endogenous enzymes causing potential toxic effects to humans. Here, we fabricate Fmoc-Tyr–OH–amygdalin hydrogel (FTOA) which represents L-tyrosine derived low molecular weight hydrogelator entrapping amygdalin. Fourier Transform Infrared Spectroscopy and Fluorescent Emission Spectrum elucidated complexation process between Fmoc-Tyr-OH (FTO). was sustainably released from FTOA at...
Xuefu Zhuyu decoction (XFZYD) performs multiple functions for traumatic brain injury (TBI) treatment. However, its clinical application is limited by the incomplete exploration of targets and inadequate discussion mechanisms. We aimed to investigate metabolic alterations XFZYD in acute chronic stages TBI. Sprague-Dawley rats were randomly divided into sham, controlled cortical impact (CCI) group. Behavioral histopathological tests used evaluate neuroprotective effects. Coagulation assays...
This study aimed to explore influencing factors and clinical significance of ultra-long-term microischemia following intracranial aneurysm (IA) embolization establish a theoretical foundation for reducing both the incidence cognitive dysfunction in patients post embolization. A retrospective analysis was conducted on data from 147 who received endovascular treatment IAs. Patients were categorized into microischemic control (non-microischemic) groups based findings high-resolution magnetic...
Abstract Acellular dermal matrix (ADM) is one of the most promising scaffold materials due to its ability retain natural extracellular structure. Micronized acellular (mADM) was prepared with no intact cell nuclei and preserved growth factors by High Hydrostatic Pressure (HHP) approach. And mADM-collagen wound dressings were developed different proportion type I collagen recombinant humanized III collagen. The porous structure made them a good candidate for preventing excessive fluid...
Xuefu Zhuyu decoction (XFZYD) is used to treat traumatic brain injury (TBI). XFZYD-based therapies have achieved good clinical outcomes in TBI. However, the underlying mechanisms of XFZYD TBI remedy remains unclear. The study aimed identify critical miRNAs and putative associated with XFYZD through comprehensive bioinformatics analysis. We established a controlled cortical impact (CCI) mice model treated XFZYD. high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS)...
The aim of the present study was to identify potential risk circulating-HPV-DNA in non-small cell lung cancer (NSCLC) and analyze abnormally expressed miRNAs circulating HPV-DNA-positive NSCLC. HPV universal primers were used detect presence HPV-DNA peripheral blood 100 patients with relationship between NSCLC characteristics analyzed. Then, eight differentially screened based on TCGA database. levels detected by real-time quantitative PCR. ROC curves generated evaluate diagnostic...