A5100635058- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Cancer, Hypoxia, and Metabolism
- Cancer Research and Treatments
- MicroRNA in disease regulation
- Cancer, Lipids, and Metabolism
- Cancer-related gene regulation
- Ferroptosis and cancer prognosis
- Breast Lesions and Carcinomas
- AI in cancer detection
- Drug Transport and Resistance Mechanisms
- Cancer-related Molecular Pathways
- Salivary Gland Disorders and Functions
- Genetics, Bioinformatics, and Biomedical Research
- NF-κB Signaling Pathways
- Cancer Cells and Metastasis
- Breast Cancer Treatment Studies
- Endoplasmic Reticulum Stress and Disease
- Cell Image Analysis Techniques
- Circular RNAs in diseases
- Cell death mechanisms and regulation
- Galectins and Cancer Biology
- HER2/EGFR in Cancer Research
- Ginseng Biological Effects and Applications
- Systemic Lupus Erythematosus Research
Jiangsu University
2024
Kunming Medical University
2013-2024
First People's Hospital of Kunshan
2024
West China Medical Center of Sichuan University
2020
M2‑like tumour‑associated macrophages (TAMs) have been demonstrated to promote the growth of anaplastic thyroid carcinoma (ATC). However, underlying mechanism TAMs in ATC remains unclear. Thus, present study, role and were investigated. induced by treatment with PMA, plus IL‑4 IL‑13, identified flow cytometry. Transwell sphere formation assays applied assess invasion stemness cells. The expression levels insulin‑like factor (IGF)‑1 IGF‑2 examined ELISA reverse transcription‑quantitative PCR....
Statement of RetractionWe, the Editors and Publisher journal Cell Cycle, have retracted following articleChao Liu, Zhiping Feng, Ting Chen, Juan Lv, Pengjie Li Jia, Jialun Zhu, Fukun Chuanzhou Yang, Zhiyong Deng. Downregulation NEAT1 reverses radioactive iodine resistance papillary thyroid carcinoma cell via miR-101-3p/FN1/PI3K-AKT signaling pathway. Cycle. 2018;18(2):167–203. doi: 10.1080/15384101.2018.1560203.Since publication, concerns been raised about integrity data in article. When...
Multidrug resistance (MDR) is an obstacle for cancer chemotherapy. It was reported that 20(S)-ginsenoside Rg3 (hereafter Rg3) able to regulate MDR in mouse leukemia cells. The present study investigated the effect of on A549 lung A cell viability assay revealed treatment increased cisplatin (DDP) cytotoxicity DDP resistant cells (A549/DDP). Furthermore, increases antitumor A549/DDP xenograft mice. expression MDR‑mediated proteins, including P‑glycoprotein (P‑gp), multidrug...
Primary Sjögren's syndrome (pSS) is a systemic autoimmune disorder with an unclear pathogenetic mechanism in the labial gland. This study aims to investigate cellular and molecular mechanisms contributing development of this disease.
Thyroid carcinoma is primarily treated by surgery combined with radioactive 131iodine (131I) treatment; however, certain patients exhibit resistance to 131I treatment. Previous research indicated that nuclear factor‑κB (NF‑κB) was associated in cancer cells. The present study aimed investigate the effects of NF‑κB on uptake and apoptosis thyroid TPC‑1 BCPAP cell lines were employed as models study, expression inhibited RNA interference (RNAi). ability cells measured viability detected an MTT...
Air pollution significantly impacts lung cancer progression, but there is a lack of comprehensive molecular characterization clinical samples associated with air pollution. Here, we performed proteogenomic analysis adenocarcinoma (LUAD) in 169 female never-smokers from the Xuanwei area (XWLC cohort), where coal smoke primary contributor to high incidence. Genomic mutation revealed XWLC as distinct subtype LUAD separate cases smoking or endogenous factors. Mutational signature suggested that...
Air pollution significantly impacts lung cancer progression, but there is a lack of comprehensive molecular characterization clinical samples associated with air pollution. Here, we performed proteogenomic analysis adenocarcinoma (LUAD) in 169 female never-smokers from the Xuanwei area (XWLC cohort), where coal smoke primary contributor to high incidence. Genomic mutation revealed XWLC as distinct subtype LUAD separate cases smoking or endogenous factors. Mutational signature suggested that...
<title>Abstract</title> <bold>Background:</bold> The traditional TNM staging system for colorectal cancer (CRC) is limited by the biological characteristics of tumors and their high heterogeneity. This study proposes a pathological signature (PScrc) based on digital pathology technology, aimed at assessing its prognostic value in overall survival (OS) disease-free (DFS) through analysis various features hematoxylin eosin (HE)-stained slides. <bold>Methods: </bold>A retrospective cohort was...
Preoperative neoadjuvant chemotherapy has become the standardized treatment for patients with locally advanced breast cancer.With wide application of in clinic,evaluation response to seems increasingly important.How evaluate curative effect timely,accurately,effectively and noninvasively focus clinical research.At present,clinical palpation,radiographic measurement pathological examination are usually used clinic,and study cancer biology factor is also rapidly spread.The status different...