A5002431300- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Traumatic Brain Injury Research
- S100 Proteins and Annexins
- Cerebrospinal fluid and hydrocephalus
- Cardiac Arrest and Resuscitation
- Trauma and Emergency Care Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Emergency and Acute Care Studies
- Ophthalmology and Eye Disorders
- Spinal Fractures and Fixation Techniques
- Occupational Therapy Practice and Research
- Acute Ischemic Stroke Management
- Nursing Education, Practice, and Leadership
- Thermal Regulation in Medicine
- Traumatic Ocular and Foreign Body Injuries
Addenbrooke's Hospital
2006-2022
University of Cambridge
2006-2022
Brain Injury Association of America
2005
The effect of decompressive craniectomy on clinical outcomes in patients with refractory traumatic intracranial hypertension remains unclear.
<h3>Importance</h3> Trials often assess primary outcomes of traumatic brain injury at 6 months. Longer-term data are needed to for patients receiving surgical vs medical treatment intracranial hypertension. <h3>Objective</h3> To evaluate 24-month with hypertension treated decompressive craniectomy or standard care. <h3>Design, Setting, and Participants</h3> Prespecified secondary analysis the Randomized Evaluation Surgery With Craniectomy Uncontrollable Elevation Intracranial Pressure...
Uncertainty remains as to the role of decompressive craniectomy (DC) for primary evacuation acute subdural haematomas (ASDH). In 2011, a collaborative group was formed in UK with aim answering following question: "What is clinical- and cost-effectiveness craniectomy, comparison craniotomy adult patients undergoing an ASDH?" The proposed RESCUE-ASDH trial (Randomised Evaluation Surgery Craniectomy Undergoing Evacuation Acute Subdural Haematoma) multicentre, pragmatic, parallel randomised DC...
Measuring health-related quality of life (HRQoL) has an important role in the comprehensive assessment patient recovery following traumatic brain injury (TBI). We examined validity domain and summary scores derived from Medical Outcomes Survey 36-Item Short Form Health Questionnaire (SF-36) as outcome measures for TBI a prospective study 514 patients with range functional impairment (Glasgow Outcome Scale–Extended [GOSE] 3–8). Item scaling criteria eight were tested principal component...
Patients undergoing neurosurgical intervention may require different types of organized rehabilitation. A prospective study was performed the care needs inpatients between ages 16 and 70 years who were in acute wards for more than 2 weeks. Only 58% bed occupancy days devoted to essential ward management. This figure even lower patients admitted with subarachnoid haemorrhage (36%) or traumatic brain injury (38%). Overall, 21% would have appropriately spent 'rapid access'/acute rehabilitation...
The fundamental pathophysiological process following head injury is the development and propagation of an escalating cycle brain swelling, increase in intracranial pressure (ICP), reduction blood supply oxygen delivery, energy failure further enhancing poor outcome. aim RESCUEicp trial (Randomised Evaluation Surgery with Craniectomy for Uncontrollable Elevation ICP) to provide class I evidence as whether decompressive craniectomy effective management patients raised refractory ICP traumatic (TBI).
The Randomized Evaluation of Surgery with Craniectomy for Uncontrollable Elevation intracranial pressure (RESCUEicp) study was undertaken to determine whether decompressive craniectomy has a role in the management patients traumatic brain injury and raised pressure. compares maximal medical craniectomy, two approaches used when all other interventions have failed control hypertension. Neither these therapies grade one evidence support its use, but both are regularly as final escalation...
The RESCUEicp study (Randomised Evaluation of Surgery with Craniectomy for Uncontrollable Elevation Intracranial Pressure) aims to provide Class 1 randomised evidence as whether decompressive craniectomy is effective the management patients raised and refractory intracranial pressure (ICP) following traumatic brain injury.
Hutchinson, P. J.; Corteen, E.; Czosnyka, M.; Mendelow, A. D.; Menon, D. K.; Mitchell, P.; Murray, G.; Pickard, J. Rickels, Sahuquillo, Servadei, F.; Teasdale, G. Timofeev, I.; Unterberg, A.; Kirkpatrick, Author Information