A5077387629- Effects and risks of endocrine disrupting chemicals
- Pharmacological Effects and Toxicity Studies
- Carcinogens and Genotoxicity Assessment
- Risk and Safety Analysis
- Pharmacogenetics and Drug Metabolism
- Chemical Safety and Risk Management
- Health, Environment, Cognitive Aging
- Anesthesia and Sedative Agents
- Toxic Organic Pollutants Impact
- Epilepsy research and treatment
- Per- and polyfluoroalkyl substances research
- Air Quality and Health Impacts
- Antibiotics Pharmacokinetics and Efficacy
- Intensive Care Unit Cognitive Disorders
- Agricultural safety and regulations
- Anesthesia and Pain Management
- Nutritional Studies and Diet
- Consumer Attitudes and Food Labeling
- Plant Toxicity and Pharmacological Properties
- Heavy metals in environment
- Heavy Metal Exposure and Toxicity
- HIV/AIDS drug development and treatment
- Pharmacology and Obesity Treatment
- Electrolyte and hormonal disorders
- Diet and metabolism studies
Federal Institute for Risk Assessment
2011-2023
University of Manchester
2022
Manchester Academic Health Science Centre
2022
Health Forecasting
2006
National Institute for Public Health and the Environment
2006
Joint Research Centre
2006
Federal Institute for Health Protection of Consumers and Veterinary Medicine
1998-2003
Gesundheitsamt
1991-1994
Freie Universität Berlin
1980-1993
Sozialwissenschaftliche Forschung und Beratung
1988
120 cases of class IC antiarrhythmic overdose, including propafenone, flecainide, ajmaline and prajmaline were evaluated with respect to clinical course, therapy outcome. Whereas drug overdose in general has an overall mortality less than 1%, intoxication drugs was associated a mean 22.5%. Nausea, which occurred within the first 30 minutes after ingestion, earliest symptom. Spontaneous vomiting probably led self-detoxication about half patients. Cardiac symptoms bradycardia and, frequently,...
The dietary exposure to selected PFAAs was estimated in four European states (Belgium, the Czech Republic, Italy and Norway) representing Western, Southern, Eastern Northern Europe. harmonised sampling programme designed Union project PERFOOD targeted at identifying seven PFAAs, including perfluorooctane sulfonic acid (PFOS) perfluorooctanoic (PFOA), food items that are most important both terms of consumption based on known high contamination patterns. average for adults (18-64 years)...
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The toxicity of lead has been known for a long time, and no safe uptake level can be derived humans. Consumers' intake via food should therefore kept as low possible. Game meat contain elevated levels due to the use ammunition hunting. A risk assessment conducted in 2010 by German Federal Institute Risk Assessment including various consumption scenarios revealed possible health extreme consumers game hunted with (i.e. hunters members hunters' households). Babies, infants, children women...
Omeprazole induces hepatic cytochrome P-4501A2. In a previous study this effect was shown to be significant in vivo 6 poor metabolizers, including 1 intermediate metabolizer, but not 12 extensive metabolizers of S-mephenytoin after 7 days treatment with 40 mg/day omeprazole. study, the specificity inducing potential omeprazole investigated these volunteers. Furthermore, eight dose-dependence P-450 1A2 induction evaluated. Cytochrome activity monitored by means 13C-[N3-methyl]caffeine breath...
Cadmium is a very toxic contaminant with food being the major source of exposure for general public. The second German consumption survey (Nationale Verzehrsstudie II - NVS II) about 20 000 participants (15 371 dietary history interviews used this study) allowed an updated assessment population. Based on these comprehensive data, information 545 individual items by population was generated. concentrations in were compiled from monitoring programme, European countries' authority programmes...
Polychlorinated dibenzo-p-dioxin and -furan (PCDD/F) dioxin-like polychlorinated biphenyl (dl-PCB) exposure from food were estimated using new consumption data the recent German survey (Nationale Verzehrsstudie II – NVS II). Based on these comprehensive data, information of 545 individual items by population was derived. Concentrations compounds in compiled Food Monitoring Programme (GFMP), Dioxin Database, other authority programmes, European countries’ programmes published literature...