A5012449429- Plant Gene Expression Analysis
- Genomics and Phylogenetic Studies
- Plant-Microbe Interactions and Immunity
- Cell Adhesion Molecules Research
- Advanced Photocatalysis Techniques
- Plant Molecular Biology Research
- Extracellular vesicles in disease
- Advanced oxidation water treatment
- Plant Reproductive Biology
- Plant Disease Resistance and Genetics
- Postharvest Quality and Shelf Life Management
- Renal Diseases and Glomerulopathies
- Plant Pathogens and Fungal Diseases
- Plant Physiology and Cultivation Studies
- Infective Endocarditis Diagnosis and Management
- COVID-19 Pandemic Impacts
- Actinomycetales infections and treatment
- Streptococcal Infections and Treatments
- COVID-19 epidemiological studies
- Advanced Nanomaterials in Catalysis
- Plant biochemistry and biosynthesis
- Adipokines, Inflammation, and Metabolic Diseases
- Plant and Fungal Interactions Research
- Botanical Studies and Applications
- Trace Elements in Health
China Medical University
2018-2024
Shanghai Clinical Research Center
2024
Tropical Crops Genetic Resources Institute
2023-2024
Chinese Academy of Tropical Agricultural Sciences
2023-2024
Ministry of Agriculture and Rural Affairs
2024
Shenyang Pharmaceutical University
2022-2024
Nanjing Agricultural University
2018-2023
Shanxi Medical University
2019-2023
National Institute for Communicable Disease Control and Prevention
2019-2023
China State Construction Engineering (China)
2023
Abstract Pathogen invasion leads to fast, local-to-systemic signal transduction that initiates plant defense responses. Despite tremendous progress in past decades, aspects of this process remain unknown, such as which cell types respond first and how signals are transferred among types. Here, we used single-cell RNA-seq >50 000 single cells document the gene expression landscape leaves woodland strawberry during infection by Botrytis cinerea identify major We constructed a atlas...
The emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) has significant challenges to human health and clinical treatment, with KPC-2-producing CRKP being the predominant epidemic strain. Therefore, there is an urgent need identify new therapeutic targets strategies. Non-coding small RNA (sRNA) a post-transcriptional regulator genes involved in important biological processes bacteria represents emerging strategy for antibiotic-resistant bacteria. In this study, we analyzed...
Chitosan oligosaccharides (COS) display various biological activities. In this study, we aimed to explore the preventive effects of COS on glucolipid metabolism disorder using palmitic acid (PA)-induced HepG2 cells and high-fat diet (HFD)-fed C57BL/6J mice as experimental models in vitro vivo, respectively. The results showed that pretreatment for 12 h significantly ameliorated lipid accumulation exposed PA 24 h, accompanied by a reversing upregulated mRNA expression proinflammatory...
Emerging zoonoses of wildlife origin caused by previously unknown agents are one the most important challenges for human health. The Qinghai-Tibet Plateau represents a unique ecological niche with diverse that harbours several pathogens and numerous uncharacterized pathogens. In this study, we identified characterized novel arenavirus (namely, plateau pika virus, PPV) from pikas (Ochotona curzoniae) on virome analysis. Isolated PPV strains could replicate in mammalian cells. We further...
Four Gram-stain-positive, catalase-negative, non-spore-forming, rod-shaped bacterial strains (zg-325 T , zg329, dk561 and dk752) were isolated from the respiratory tract of marmot ( Marmota himalayana ) faeces Tibetan gazelle Procapra picticaudata Qinghai-Tibet Plateau PR China. The results 16S rRNA gene sequence-based phylogenetic analyses indicated that zg-325 represent members genus Actinomyces most similar to denticolens DSM 20671 ruminicola B71 respectively. DNA G+C contents 71.6 69.3...
Two pairs of aerobic, Gram-stain-positive, rod-shaped strains (HY164T/HY044, HY168T/HY211) were isolated from bat faecal samples. Strains HY164T and HY044 motile with a polar flagellum, had 16S rRNA gene similarity 95.1-98.6 % to Haloactinobacterium album YIM 93306T glacieicola T3246-1T; HY168T HY211 most similar Ruania albidiflava DSM 18029T (96.6 %). Phylogenetic trees based on whole genome sequences revealed affiliation the family Ruaniaceae, representing novel lineages in genera Ruania,...
Four bacterial strains (LJ126T/S18 and Z-34T/S20) recovered from faecal samples of Tibetan antelopes on the Qinghai-Tibet Plateau China were analysed using a polyphasic approach. All four isolates aerobic, short rod-shaped, non-motile, Gram-stain-positive, acid-fast fast-growing. Phylogenetic analyses based upon 16S rRNA whole-genome sequences showed that two pair formed distinct branches within evolutionary radiation genus Mycolicibacterium. Strains LJ126T/S18 Z-34T/S20 most closely related...
GRAS genes formed one of the important transcription factor gene families in plants, had been identified several plant species. The family were involved growth, development, and stress resistance. However, comparative analysis Rosaceae species was insufficient.In this study, a total 333 six species, including 51 strawberry (Fragaria vesca), 78 apple (Malus domestica), 41 black raspberry (Rubus occidentalis), 59 European pear (Pyrus communis), 56 Chinese rose (Rosa chinensis), 48 peach...
In the present study, four bacterial strains, two (S-713 T and 406) isolated from faecal samples of Tibetan antelopes other (S-531 1598) leaves dandelion collected on Qinghai–Tibet Plateau PR China, were analysed using a polyphasic approach. All isolates aerobic, rod-shaped, non-motile, oxidase-negative, Gram-stain-positive catalase-positive. According to phylogenetic trees, strain pairs S-713 /406 S-531 /1598 form independent branches belonging genus Nocardioides , are closest...
Necrotrophic pathogens replicate massively upon colonizing plants, causing large-scale wilting and death of plant tissues. Understanding both mechanisms pathogen invasion host response processes prior to symptom appearance their key regulatory networks is therefore important for defense against attack. Here, we investigated the interaction between woodland strawberry (Fragaria vesca) leaves gray mold (Botrytis cinerea) at 14 infection time points during first 12 hours period using a dense,...
Catabolic control protein (CcpA) is linked to complex carbohydrate utilization and virulence factor in many bacteria species, influences the transcription of target genes by mechanisms. To characterize activity regulatory mechanisms CcpA Streptococcus sanguinis, here, we analyzed transcriptome sanguinis SK36 its CcpA-null derivative (△CcpA) using RNA-seq. Compared regulon RegPrecise database, found that only minority differentially expressed (DEGs) contained putative catabolite response...
SQUAMOSA-promoter binding protein-like (SPL) proteins are plant-specific transcript factors that play essential roles in plant growth and development. Although many SPL genes have been well characterized model plants like Arabidopsis, rice tomato, the functions of SPLs strawberry still largely elusive. In present study, we cloned FvSPL10, ortholog AtSPL9, from woodland strawberry. Subcellular localization shows FvSPL10 localizes cell nucleus. The luciferase system assay indicates is a...
Abstract Background The plant hormone auxin is widely involved in growth, development, and morphogenesis, the TIR1/AFB AUX/IAA proteins are closely linked to rapid response signal transmission. However, their evolutionary history, historical patterns of expansion contraction, changes interaction relationships still unknown. Results Here, we analyzed gene duplications, interactions, expression TIR1/AFBs AUX/IAAs understand underlying mechanisms evolution. ratios range from 4:2 Physcomitrium...
WRKY protein is one of the largest plant-specific transcription factors that plays critical roles in plant stress responses, but few have been functionally analyzed strawberry. In this study, a Botrytis cinerea response gene, FvWRKY50, was isolated from woodland Expression analysis indicated transcript FvWRKY50 gradually decreased with fruit ripening, significantly induced by B. infection mature strawberry fruit. Subcellular localization assay revealed localized nucleus. Several cis-elements...
The re-emerging outbreak of COVID-19 in Beijing, China, the summer 2020 originated from a SARS-CoV-2-infested wholesale food supermarket. We postulated that Xinfadi market has links with food-trade activities. Our Susceptible to disease, Infectious, and Recovered coupled Agent Based Modelling (SIR-ABM) analysis for studying diffusion SARS-CoV-2 particles suggested trade-distancing strategy effectively reduces reproduction number (R0). retail shop closure reduced visitors by nearly half. In...
New Delhi metallo-beta-lactamase-5 (NDM-5)-producing carbapenem-resistant
<title>Abstract</title> Mango, a typical respiratory climacteric fruit, is susceptible to short shelf life and quality deterioration during post-harvest ripening. Though low temperature can prolong the storage time significantly, its side effects on fruit remains be elucidated. Through combination of transcriptome metabolome analyses, this study aimed elucidate low-temperature biosynthesis volatile organic compounds (VOCs), flavonoids, sucrose, degradation acids. Carbohydrate-related...