A5101615041- Genomics and Phylogenetic Studies
- Vaccine Coverage and Hesitancy
- Hepatitis B Virus Studies
- Actinomycetales infections and treatment
- SARS-CoV-2 and COVID-19 Research
- COVID-19 epidemiological studies
- Identification and Quantification in Food
- Hepatitis C virus research
- Molecular Biology Techniques and Applications
- Circular RNAs in diseases
- Influenza Virus Research Studies
- Hepatitis Viruses Studies and Epidemiology
- Plant Disease Resistance and Genetics
- Plant Pathogens and Fungal Diseases
- Microbial infections and disease research
- Cancer-related molecular mechanisms research
- Autism Spectrum Disorder Research
- RNA modifications and cancer
- Liver Disease Diagnosis and Treatment
- Cryospheric studies and observations
- Gaze Tracking and Assistive Technology
- Microbial Community Ecology and Physiology
- Temporomandibular Joint Disorders
- Bacteriophages and microbial interactions
- Genetics, Aging, and Longevity in Model Organisms
Peking University
2021-2025
Beijing Jiaotong University
2023-2024
National Institute for Communicable Disease Control and Prevention
2019-2024
Taizhou People's Hospital
2019-2024
Nantong University
2015-2024
Northeastern University
2024
Yanbian University
2024
Fujian Medical University
2011-2024
Institute of Mountain Hazards and Environment
2023-2024
Chinese Academy of Sciences
2023-2024
China, which has the largest chronic hepatitis B virus (HBV) burden, may expand antiviral therapy to attain World Health Organization (WHO)-2030 goal of 65% reduction in mortality. We evaluated health outcomes and cost-effectiveness HBV infection treatments based on alanine transaminase (ALT) treatment initiation thresholds coverage China identify an optimal strategy. A decision-tree Markov state-transition model expanded for by simulating 136 scenarios ALT (40 U/L, 35 U/L males 25 females,...
Cell culture is an essential tool to study cell function. In C. elegans the ability isolate and cells has been limited embryonically derived cells. However, or blastomeres isolated from mixed stage embryos terminally differentiate within 24 hours of culture, thus precluding post-embryonic culture. We have developed efficient technically simple method for large-scale isolation primary larval-stage optimized treatment maximize number minimize death each four larval stages. obtained up 7.8×104...
The Nineteenth National Congress of the Communist Party China put forward implementation a rural revitalization strategy, which is an important way to achieve common prosperity for all people, as promoting farmers’ income increase and narrowing urban–rural gap are key prosperity. So, under background vigorously strategy in China, it very explore effect realization mechanism geographical indication (GI) on reducing gap. Based statistical data 31 provinces from 2008 2019, this empirical study...
Abstract Sustainable development is the power source to promote rural economic and social prosperity necessary guarantee for revitalization, while relative poverty alleviation inherent requirement promoting sustainable realizing revitalization. The pro‐agricultural attribute of geographical indication determines that it can be an important tool alleviate poverty. This study analyzes relationship between alleviation, as well mediating role agricultural industry agglomeration moderating scale...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine hesitancy is associated with community aggregation, inducing low coverage and potentially more frequent community-level outbreak. Addressing in settings should be a priority for healthcare providers. A cross-sectional online questionnaire survey was conducted during June July 2022. Ten sites were set up eastern, central, western China, from where residents recruited setting. In total, 7,241 71 communities included. Of the...
Glacial lake outburst floods (GLOFs) are one of the most severe disasters in alpine regions, releasing a large amount water and sediment that can cause fatalities economic loss as well substantial damage to downstream infrastructures. The risk GLOFs Himalayas is exacerbated by glacier retreat caused global warming. Critical corridors, such Rongxer Watershed, threatened GLOFs, but lack assessment specific watershed hinders hazard prevention. In this study, we propose novel model evaluate GLOF...
Abstract There is increased recognition that sensory neurons located in dorsal root ganglia (DRG) are affected amyotrophic lateral sclerosis (ALS). However, it remains unknown whether ALS-inducing factors, other than mutant superoxide dismutase 1 (SOD1 G93A ), directly affect neurons. Here, we examined the effect of TAR DNA-binding protein (TDP43 A315T ) on culture and vivo . In parallel, reevaluated expressing SOD1 We found cultured harboring either TDP43 or grow neurites at a slower rate...
Eight Gram-stain-positive, rod-shaped bacterial strains were isolated from faeces of Tibetan antelopes on the Tibet-Qinghai Plateau China. Genomic sequence analysis showed that belong to genera Actinomyces (strains 299T and 340), Corynebacterium 2184T, 2185, 2183T 2189) Oceanobacillus 160T 143), respectively, with a percentage similarity for 16S rRNA gene under species threshold 98.7 % except 143 arenosus CAU 1183T (98.8 %). The genome sizes (and genomic G+C contents) 3.1 Mb (49.4 %), 2.5...
Two Gram-stain-positive, irregular rod-shaped (0.2-0.5×1.3-2.5 um) strains, HY056T and HY057, were isolated from the faeces of Equus kiang (the largest wild asses) collected at different regions Qinghai-Tibetan Plateau PR China. Phylogenetic analyses indicated that strains HY057 belong to genus Nocardioides by sharing a similarity ranging 96.3 97.0 % in 16S rRNA gene sequence forming distinct cluster with daphniae JCM 16608T, houyundeii 78T, solisilvae Ka25T gilvus XZ17T. The digital DNA-DNA...
Six aerobic, non-motile, non-haemolytic, Gram-stain-negative, oxidase-negative strains (185 T , 187, 323-1 194, dk386 and dk771) were recovered from different faecal samples of Equus kiang on the Qinghai–Tibet Plateau. In 16S rRNA gene sequences, one strain pair, 185 /187, shared highest similarity to Acinetobacter equi 114 (97.9 %), other two (323-1 /194 dk771 /dk386) harbinensis CGMCC 1.12528 (98.6 97.0 %, respectively). Phylogenomic tree analysis showed that these six formed three...
Four Gram-stain-positive, catalase-negative, non-spore-forming, rod-shaped bacterial strains (zg-325 T , zg329, dk561 and dk752) were isolated from the respiratory tract of marmot ( Marmota himalayana ) faeces Tibetan gazelle Procapra picticaudata Qinghai-Tibet Plateau PR China. The results 16S rRNA gene sequence-based phylogenetic analyses indicated that zg-325 represent members genus Actinomyces most similar to denticolens DSM 20671 ruminicola B71 respectively. DNA G+C contents 71.6 69.3...
Two strains of Gram-stain-positive, aerobic, non-spore-forming, non-motile, rod-shaped bacteria (designated dk512T and dk508) were isolated from the faeces Tibetan gazelle (Procapra picticaudata) collected Qinghai-Tibet Plateau, PR China. The 16S rRNA gene sequences showed highest identity to Microbacterium saccharophilum K-1T (98.0 97.9 % similarity, respectively). phylogenetic analysis based on revealed that dk508 members genus Microbacterium, most closely related mitrae M4-8T hatanonis...
Two novel Gram-stain-positive, irregular rod-shaped actinomycetes, S-1144 T and 4053, were isolated from leaves of Lamiophlomis rotata on the Qinghai–Tibet Plateau, PR China. Cells aerobic, catalase-positive oxidase-negative. Colonies Reasoner’s 2A agar light yellow, circular, shiny, smooth convex after 2 days incubation. The isolates grew optimally at 25 °C, pH 7.5 with 0 % (w/v) NaCl. results polyphasic analyses indicated that strain belonged to genus Nocardioides its close phylogenetic...
Zero-shot learning (ZSL) aims to identify novel categories via transferring shared semantic knowledge from seen classes unseen ones. Since labeled samples of are unavailable in training phase, visual and spaces difficult align precisely. Besides, the uncertainties inherent fixed features predefined prototypes always neglected, which also play important roles modeling unbiased visual-semantic embeddings. In this paper, we propose a Dual-uncertainty Guided Cycle-consistent Network (DGCNet) for...
Treatments for infectious bone defects such as periodontitis require antibacterial and osteogenic differentiation capabilities. Nanotechnology has prompted the development of multifunctional material. In this research, we aim to synthesize a nanoparticle that can eliminate periodontal pathogenic microorganisms simultaneously stimulate new tissue regeneration mineralization. QAS-modified core-shell mesoporous silica containing Ag nanoparticles (Ag@QHMS) was successfully synthesized through...