A5102723312- Genomics and Phylogenetic Studies
- Actinomycetales infections and treatment
- Magnetism in coordination complexes
- Bacteriophages and microbial interactions
- Microbial infections and disease research
- Crystal structures of chemical compounds
- Microbial Natural Products and Biosynthesis
- Plant Disease Resistance and Genetics
- Organic and Molecular Conductors Research
- Bacterial Identification and Susceptibility Testing
- Identification and Quantification in Food
- Computational Drug Discovery Methods
- Organometallic Compounds Synthesis and Characterization
- Escherichia coli research studies
- Organometallic Complex Synthesis and Catalysis
- Probiotics and Fermented Foods
- Antibiotic Resistance in Bacteria
- Perovskite Materials and Applications
- Ophthalmology and Eye Disorders
- Microbial Metabolism and Applications
- Ginseng Biological Effects and Applications
- Diverse Scientific and Economic Studies
- Metal-Organic Frameworks: Synthesis and Applications
- Berberine and alkaloids research
- Metalloenzymes and iron-sulfur proteins
National Institute for Communicable Disease Control and Prevention
2016-2023
First Affiliated Hospital of Nanchang University
2023
Nanchang University
2023
Hebei Agricultural University
2021
Innovation Cluster (Canada)
2021
Army Medical University
2015-2018
South China Agricultural University
2013-2018
Huazhong University of Science and Technology
2010
As a core microbe of the human gut ecosystem, Bacteroides vulgatus has been linked to multiple aspects metabolic disorders in collection associative studies, which, while indicative, warrants more direct experimental evidence verify. In this study, we experimentally demonstrated that oral administration B. Bv46 ameliorated serum lipid profile and systemic inflammation high-fat diet-induced hyperlipidemic rats microbiome-regulated manner, which appears be associated with changes bile acid...
Escherichia coli is both of a widespread harmless gut commensal and versatile pathogen humans. Domestic animals are well-known reservoir for pathogenic E. coli. However, studies populations from wild that have been separated human activities had very limited. Here we obtained 580 isolates intestinal contents 116 Marmot Marmota himalayana Qinghai-Tibet plateau, China, with five per animal. We selected 125 (hereinafter referred to as strains) the genome sequencing, based on unique pulse field...
Hypervirulent Klebsiella pneumoniae (hvKp) can cause serious infections and has been increasingly reported clinically. However, we still lack the knowledge to what degree hvKp colonize community. In this study, investigated colonization of in healthy human gut relationship between clinically important invasive strains. We compile global genomes K. for in-depth genetic analysis found most originated from Chinese datasets; therefore, collected isolates people around China. The results revealed...
The subfamily Caesalpinioideae of the Fabaceae has long been recognized as non-monophyletic due to its controversial phylogenetic relationships. Cercis chuniana, endemic China, is a representative species L. placed within in older sense. Here, we report whole chloroplast (cp) genome C. chuniana and compare it six other from Caesalpinioideae. Comparative analyses gene synteny simple sequence repeats (SSRs), well estimation nucleotide diversity, relative ratios synonymous nonsynonymous...
Extensions of mesenchymal stem cells (MSCs) in vitro may lead to the loss their biological functions. However, hypoxic culturation has been shown enhance proliferation, survival, and immunomodulatory capacity MSCs.We aimed investigate effects long-term cultivation on properties human umbilical cord-derived MSCs (hUCMSCs) therapeutic extracellular vesicles (EVs) allergic rhinitis (AR).Proliferation, senescence, telomerase activity multipotent hUCMSCs were analyzed under hypoxia (1%) or...
Eight Gram-stain-positive, rod-shaped bacterial strains were isolated from faeces of Tibetan antelopes on the Tibet-Qinghai Plateau China. Genomic sequence analysis showed that belong to genera Actinomyces (strains 299T and 340), Corynebacterium 2184T, 2185, 2183T 2189) Oceanobacillus 160T 143), respectively, with a percentage similarity for 16S rRNA gene under species threshold 98.7 % except 143 arenosus CAU 1183T (98.8 %). The genome sizes (and genomic G+C contents) 3.1 Mb (49.4 %), 2.5...
Two Gram-stain-positive, irregular rod-shaped (0.2-0.5×1.3-2.5 um) strains, HY056T and HY057, were isolated from the faeces of Equus kiang (the largest wild asses) collected at different regions Qinghai-Tibetan Plateau PR China. Phylogenetic analyses indicated that strains HY057 belong to genus Nocardioides by sharing a similarity ranging 96.3 97.0 % in 16S rRNA gene sequence forming distinct cluster with daphniae JCM 16608T, houyundeii 78T, solisilvae Ka25T gilvus XZ17T. The digital DNA-DNA...
Six aerobic, non-motile, non-haemolytic, Gram-stain-negative, oxidase-negative strains (185 T , 187, 323-1 194, dk386 and dk771) were recovered from different faecal samples of Equus kiang on the Qinghai–Tibet Plateau. In 16S rRNA gene sequences, one strain pair, 185 /187, shared highest similarity to Acinetobacter equi 114 (97.9 %), other two (323-1 /194 dk771 /dk386) harbinensis CGMCC 1.12528 (98.6 97.0 %, respectively). Phylogenomic tree analysis showed that these six formed three...
Four novel bacterial strains (zg-ZUI122T/zg-ZUI10 and zg-ZUI227T/zg-ZUI100) were isolated from the intestinal contents of Marmota himalayana characterized using a polyphasic approach. Cells Gram-stain- catalase-positive, urease- oxidase-negative. Strains grew optimally at 28-30 °C, pH 7.0, with 0.5 % NaCl (w/v). A comparative analysis 16S rRNA gene sequences revealed that strain pairs zg-ZUI122T/zg-ZUI10 zg-ZUI227T/zg-ZUI100 belonged to genus Arthrobacter most closely related citreus DSM...
Four unknown strains belonging to the genus Arthrobacter were isolated from plateau wildlife on Qinghai-Tibet Plateau of PR China. Phylogenetic analysis based 16S rRNA gene sequences showed that four isolates separated into two clusters. Cluster I (strains 785T and 208) had greatest sequence similarity citreus (98.6 98.7 %, respectively), luteolus (98.0 98.1%, gandavensis (97.9 98.0 respectively) koreensis (97.6 97.7 respectively). Likewise, cluster II J391T J915) highest ruber 98.3 agilis...
Four aerobic, Gram-stain-positive, rod-shaped bacteria (HY60 T , HY54, HY82 and HY89) were isolated from bat faeces of Hipposideros Rousettus species collected in PR China. Phylogenetic analyses based on 16S rRNA gene sequences indicated that the four novel strains formed two separate but adjacent subclades close to Microbacterium agarici CGMCC 1.12260 (97.6–97.7 % similarity), humi JCM 18706 (97.3–97.5 %) lindanitolerans 30493 (97.3–97.4 %). The sequence similarity was 98.3 between HY60...
Two pairs of aerobic, Gram-stain-positive, rod-shaped strains (HY164T/HY044, HY168T/HY211) were isolated from bat faecal samples. Strains HY164T and HY044 motile with a polar flagellum, had 16S rRNA gene similarity 95.1-98.6 % to Haloactinobacterium album YIM 93306T glacieicola T3246-1T; HY168T HY211 most similar Ruania albidiflava DSM 18029T (96.6 %). Phylogenetic trees based on whole genome sequences revealed affiliation the family Ruaniaceae, representing novel lineages in genera Ruania,...
Four Gram-stain-positive, non-motile and asporous bacilli (strains ZJ-599 T , ZJ-621, MC1420 MC1482), isolated from animal tissue environmental samples collected on the Qinghai-Tibet Plateau, PR China, were taxonomically characterized. Based results of 16S rRNA gene sequence analyses, closest relatives strains ZJ-621 Corynebacterium endometrii LMM-1653 (97.5 %), phocae M408/89/1 (96.5 %) flavescens OJ8 (96.3 whereas MC1482 to sanguinis CCUG 58655 (98.9 mycetoides DSM 20632 (98.4...
Six novel strains (ZJ34 T , ZJ561, ZJ750 ZJ1629, zg-993 and zg-987) isolated from faeces respiratory tracts of Marmota himalayana the Qinghai–Tibet Plateau PR China were characterized comprehensively. The results analyses 16S rRNA gene genome sequences indicated that six represent three species genus Actinomyces are closely related to urogenitalis DSM 15434 (16S similarities, 94.9–98.7 %), weissii CCUG 61299 (95.6–96.6 bovis CCTCC AB2010168 (95.7 %) bowdenii 15435 (95.2–96.4 with values...
Two novel Gram-stain-positive, irregular rod-shaped bacterial strains, dk3136T and dk3543, were isolated from the faeces of Tibetan gazelle (Procapra picticaudata) in Qinghai-Tibet Plateau PR China. The cells aerobic, oxidase-negative catalase-positive. Colonies yellowish, circular without any observable aerial mycelium after culturing at 28 ℃ for 3 days on brain-heart infusion (BHI) agar with 5 % sheep blood. grew optimally °C, pH 7.5 1 (w/v) NaCl BHI supplemented Phylogenetic analysis 16S...
Background The impact of strabismus on visual function, self-image, self-esteem, and social interactions decrease health-related quality life (HRQoL).The purpose this study was to evaluate refine the adult questionnaire (AS-20) by using Rasch analysis among Chinese patients with strabismus. Methods We evaluated fitness AS-20 model in population assessing unidimensionality, infit outfit, person item separation index reliability, response ordering, targeting differential functioning (DIF)....
Two strains (S-1072T and 1626) of Gram-stain-negative, oxidase- catalase-positive, aerobic, rod-shaped, motile bacteria with a single polar flagellum, were isolated from the leaves Dandelion (Taraxacum officinale) on Qinghai-Tibet Plateau China. The cells grew optimally at 28 °C, pH 7.0 0.5 % (w/v) NaCl brain-heart infusion agar. Phylogenetic analysis based 16S rRNA gene sequences revealed that S-1072T 1626 belong to genus Luteimonas, sharing highest similarity Luteimonas arsenica CCTCC AB...
Substantial challenges have been reported in China terms of the large number adult patients with strabismus and their poor quality life. Quality life is a cultural concept that varies according to personal feelings perceptions, it influenced by physical, psychological social factors. However, date, there has no mixed-method research Chinese strabismus, conceptual model reported. This study aimed utilize mixed methods explore influence on health-related develop model.Thirty from three...
Four Gram-stain-negative, oxidase-positive, non-motile, cocci-shaped bacteria strains (ZJ106T, ZJ104, ZJ785T and ZJ930) were isolated from marmot respiratory tracts. Phylogenetic analyses based on 16S rRNA genes, 53 ribosomal protein sequences 441 core genes supported that all four belonged to the genus Neisseria with close relatives weixii 10022T iguanae ATCC 51483T. Average nucleotide identity (ANI) digital DNA-DNA hybridization (dDDH) values below species-level thresholds (95-96 % for...
Aconitum reclinatum is the only representative species of subg. Lycoctonum in North America, with restricted ranges and endangered populations. Polymorphic microsatellite markers were developed for A. further investigation genetic diversity population structure. Using Illumina HiSeq technology, we sequenced a genomic library identification simple sequence repeat markers. A total 12 polymorphic primer pairs tested on 66 individuals from four populations America. The number alleles ranged one...