- Retinal Diseases and Treatments
- Retinal and Macular Surgery
- Retinal Imaging and Analysis
- Ocular Infections and Treatments
- Intraocular Surgery and Lenses
- Ocular Diseases and Behçet’s Syndrome
- Glaucoma and retinal disorders
- Traditional Chinese Medicine Analysis
- Retinal Development and Disorders
- Bacterial Identification and Susceptibility Testing
- Vascular Malformations Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Corneal surgery and disorders
- Corneal Surgery and Treatments
- Phytochemical Studies and Bioactivities
- Neuroinflammation and Neurodegeneration Mechanisms
- Ocular Surface and Contact Lens
- Atherosclerosis and Cardiovascular Diseases
- Angiogenesis and VEGF in Cancer
- Traditional Chinese Medicine Studies
- Plant-based Medicinal Research
- Nanoplatforms for cancer theranostics
- Pulmonary Hypertension Research and Treatments
- Autophagy in Disease and Therapy
- Flavonoids in Medical Research
Shanxi Eye Hospital
2012-2025
Shanxi Medical University
2022-2025
Guangdong Food and Drug Vocational College
2020
Peking University
2008
Background: Lactylation is increasingly recognized to play a crucial role in human health and diseases. However, its involvement age-related macular degeneration (AMD) remains largely unclear. Objective: The aim of this study was identify characterize the pivotal lactylation-related genes explore their underlying mechanism AMD. Methods: Gene expression profiles AMD patients control individuals were obtained integrated from GSE29801 GSE50195 datasets. Differentially expressed (DEGs) screened...
"Tinglizi", the ripe seed of Descurainia sophia and Lepidium apetalum, is a member Brassicaceae (Cruciferae). Traditionally, former called "Nantinglizi" (Descurainiae Semen) while latter "Beitinglizi" (Lepidii Semen). In theory traditional Chinese medicine, it has power to purge lung-fire, relieve dyspnea, promote diuresis reduce edema, mainly indicated in case with phlegm-fluid accumulation, cough excessive sputum, dyspnea being unable lie, general swelling. view its wide-spread application...
Abstract Purpose To compare morphological changes in the anterior capsule of two intraocular lenses (IOLs) with different edge designs 6 months after femtosecond laser-assisted capsulotomy surgery (FLACs). Methods This study included 168 eyes from168 patients undergoing FLACs. Group A 74 from who had an Acrysof IQ Restor SN6AD3 IOL implantation a flat and B 94 TECNIS Multifocal ZMB00 "peak-like" edge. All were followed up for months. We assessed including variation opening diameters lens...
Currently, the genus Paracoccus comprises 76 recognized species. Members of are mostly isolated from environmental, animal, and plant sources. This report describes proposes a novel species clinical specimens human ocular surface. We two aerobic, Gram-stain-negative, non-spore-forming, coccoid or short rod-shaped, non-motile strains (designated DK398T DK608) conjunctival sac swabs healthy volunteers. The results showed that grew best under conditions 28°C, pH 7.0, 1.0 % (w/v) NaCl. Sequence...
Purpose: To evaluate the multifocal electroretinogram (mfERG) and optical coherence tomography (OCT) angiography features in patients with idiopathic macular hole (IMH) before after vitrectomy. Patients Methods: This prospective study was conducted at Shanxi Eye Hospital from January 2019 to December 2021. Twenty-five eyes of 25 unilateral IMH, unaffected fellow eyes, 30 healthy were investigated. All IMH underwent Results: The had significantly delayed latency (rings 2– 5) mfERG compared...
Objectives To characterize the healthy ocular surface microbiota at species level, including cultured and uncultured taxa. Methods We integrated metataxonomic method with culturomics genome sequencing analysis of selected isolated strains to better illustrate taxonomic structure microbiota. The metataxonomics used full-length 16S rRNA gene sequences operational phylogenetic unit strategy, which can precisely identify or potentially new taxa level based on tree constructed. Results detected...
Objectives: In this article, we provide a database of nonproliferative diabetes retinopathy, which focuses on early retinopathy with hard exudation, and further explore its clinical application in disease recognition. Methods: We collect the photos taken by Optos Panoramic 200 laser scanning ophthalmoscope, filter out pictures poor quality, label exudative lesions images under guidance professional medical personnel. To validate effectiveness datasets, five deep learning models are used to...
Age-related macular degeneration (AMD) is the leading cause of blindness in elderly, but therapies are not satisfactory. This study aimed to find AMD specific features through analysis high-throughput sequencing.
It is acknowledged that hepatocellular carcinoma (HCC) cause the most cancer-associated mortality all around world and traditional Chinese medicine has been widely used in HCC treatment. Physalin B (PB) important chemical compounds of a herb, Physalis alkekengi var. franchetii . In this research, it first time we illustrated PB exhibits obvious apoptotic activity SMMC-7721 HepG2 human cell lines does-dependent way. Moreover, decrease mitochondrial membrane potential (MMP) was found cellular...
In this work, two coordination polymers (CPs) based on Co(II) ions, namely, [CoL] (1) and [Co(HL) 2 (bpe) 1.5 ] (2) (H L: naphthalene-1,2-dicarboxylic acid, where L HL are the fully partially deprotonated forms of H L, respectively, bpe denotes 1,2-di[pyridin-4-yl]ethane), were prepared successfully characterized systemically through PXRD, X-ray single-crystal diffraction analysis, IR spectroscopy, EA. The application fresh CPs in treatment diabetic retinopathy was investigated, its...
To discriminate Descurainiae Semen and Pantagirus Semen.A high-performance liquid chromatographic method was developed to establish the fingerprint of Semen, hierarchical cluster analysis (HCA) partial least squares discriminant (PLS-DA) were applied study HPLC fingerprinting chemical recognition.There exists large difference peaks its relative peak area fingerprints between after conducting statistical analysis, result demonstrated that all samples classified into three categories: their...
Abstract Purpose : To evaluate the changes of choroidal blood flow area (CBFA) and absence diameter Ellipsoid zone with idiopathic macular hole (IMH) before after surgery its correlation visual function. Patients methods: This prospective study was conducted in Shanxi Eye Hospital from August 2019 to December 2021. Twenty-five eyes 25 patients unilateral IMH were investigated. The area, thickness measured eye. Meanwhile, we further explored their relationship. Results: After surgery, all...
Abstract Purpose To analyze the etiology and etiological characteristics of infectious endophthalmitis, improve cognition guide rational choices early-stage empirical drugs in clinical practice. Methods A cross-sectional study. The medical records 248 patients diagnosed with endophthalmitis Shanxi Eye Hospital from January 2016 to December 2020 were reviewed analyzed. Rrsults Of all 185 male 63 female, aged 4 87 (51.28±18.33) years. Open eye trauma intraocular surgery main causative factors....