A5100680964- Head and Neck Cancer Studies
- Head and Neck Surgical Oncology
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Allergic Rhinitis and Sensitization
- Radiomics and Machine Learning in Medical Imaging
- Mycobacterium research and diagnosis
- Oral health in cancer treatment
- Lung Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Sinusitis and nasal conditions
- Traditional Chinese Medicine Studies
- Lung Cancer Treatments and Mutations
- Foreign Body Medical Cases
- Infectious Diseases and Tuberculosis
- Tuberculosis Research and Epidemiology
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Vehicle emissions and performance
- Sarcoma Diagnosis and Treatment
- Plant-based Medicinal Research
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Complementary and Alternative Medicine Studies
- Case Reports on Hematomas
Princess Margaret Cancer Centre
2014-2025
University of Toronto
2014-2025
United Imaging Healthcare (China)
2025
Qingdao University
2021-2024
Yuhuangding Hospital
2023-2024
Xi’an University of Posts and Telecommunications
2024
Sun Yat-sen University
2023
Fifth Affiliated Hospital of Sun Yat-sen University
2023
Capital Medical University
2008-2023
Union Hospital
2023
Purpose To refine stage and prognostic group for human papillomavirus (HPV) –related nonmetastatic (M0) oropharyngeal cancer (OPC). Methods All patients with p16-confirmed OPC treated radiotherapy or without chemotherapy from 2000 to 2010 were included. Overall survival (OS) was compared among TNM stages HPV-related HPV-unrelated separately. For OPC, recursive partitioning analysis (RPA) derived new RPA objectively. Cox regression used calculate adjusted hazard ratios (AHRs) derive AHR...
Objective There is a need for early detection of colorectal cancer (CRC) at precancerous-stage adenoma. Here, we identified novel faecal bacterial markers diagnosing Design This study included 1012 subjects (274 CRC, 353 adenoma and 385 controls) from two independent Asian groups. Candidate were by metagenomics validated targeted quantitative PCR. Results Metagenomic analysis ‘ m3 ’ Lachnoclostridium sp., Fusobacterium nucleatum ( Fn ) Clostridium hathewayi Ch to be significantly enriched in...
The objective of this study was to investigate the prognostic value pretreatment circulating neutrophil count (CNC), monocyte (CMC), and lymphocyte (CLC) in human papillomavirus (HPV)-related (HPV+) HPV-unrelated (HPV-) oropharyngeal cancer (OPC).All p16-confirmed HPV+ HPV- OPC cases treated with chemoradiotherapy from 2000 2010 were included. Overall survival (OS) recurrence-free (RFS) compared for high low CNCs, CMCs, CLCs (dichotomized by median values). A multivariate analysis (MVA)...
Background The treatment of patients with MDR- and XDR-TB is usually more complex, toxic costly less effective than other forms TB. However, there little information available on risk factors for poor outcomes in China. Methodology/Principal Findings We retrospectively analyzed the clinical records HIV-negative TB Patients culture-proven or who were registered from July 2006 to June 2011 at five large-scale Tuberculosis Specialized Hospitals Among 1662 HIV-seronegative cases which...
ABSTRACT Background Body mass index (BMI) has been associated variably with head and neck cancer outcomes. We evaluated the association between BMI at either diagnosis or early adulthood Methods Patients invasive squamous cell Princess Margaret Cancer Centre in Toronto, Canada, were surveyed on tobacco alcohol exposure, performance status, comorbidities, diagnosis. A subset also had data collected for adulthood. Results With a median follow‐up of 2.5 years, 1279 analyzed patients, being...
Diarrhea-predominant irritable bowel syndrome (IBS-D) is one common chronic functional disease of the digestive system with limited treatments. The microbiota–gut–brain axis (MGBA) has a central function in pathogeny IBS-D, which includes participation many various factors, such as brain-gut peptides (BGPs), immune inflammation and intestinal flora. Inspired by drug combination traditional Chinese medicine (TCM), our previous study discovered that BBR BA could form natural self-assemblies...
Background The objective of this study was to identify a subgroup patients with head and neck squamous cell carcinoma (HNSCC) who might be suitable for hypofractionated radiotherapy (RT‐hypo) during the COVID‐19 pandemic. Methods HNSCC cases (oropharynx/larynx/hypopharynx) treated definitive RT‐hypo (60 Gy in 25 fractions over 5 weeks), moderately accelerated (RT‐acc) alone (70 35 6 or concurrent chemoradiotherapy (CCRT) 2005‐2017 were included. Locoregional control (LRC) distant (DC) after...
<h3>BACKGROUND AND PURPOSE:</h3> Addressing the performance of an imaging-based parameter compared to a “gold standard” pathologic measurement is essential achieve accurate clinical T-classification. Our aim was determine radiologic-pathologic tumor thickness correlation and its prognostic value in oral squamous cell carcinoma. <h3>MATERIALS METHODS:</h3> All T1–T3 (seventh edition <i>Cancer Staging Manual</i> American Joint Committee on Cancer) carcinomas diagnosed between 2010 2015 were...
Abstract Background The purpose of this study was to compare the clinicoradiologic characteristics human papillomavirus (HPV)‐related (HPV‐positive) and HPV‐unrelated (HPV‐negative) oropharyngeal carcinoma (OPC). Methods Primary tumor lymph node features HPV‐positive HPV‐negative OPCs from 2008 2013 were compared on pretreatment CT/MRI. Intrarater/interrater concordance assessed. Multivariable analyses identified factors associated with HPV‐positivity be used in nomogram construction....
Objective . The purpose of this study was to explore the association nine types Traditional Chinese Medicine (TCM) constitution with five chronic diseases: hypertension, hyperlipidemia, diabetes mellitus, heart disease, and obesity. Methods Chi‐squared test performed investigate distribution characteristics TCM constitutions in participants diseases questionnaire. Correspondence analysis used correlation between them. Results A total 2,660 (1,400 males; 1,260 females) were included study....
The course of patients with type B aortic intramural hematoma (IMH) is unstable, and different studies have shown that the evolution this IMH highly heterogeneous. This study sought to explore value radiomics in predicting prognosis IMH, develop validate a prediction model progression. A total 119 who had not undergone surgical or thoracic endovascular repair treatment were enrolled study. These divided into progressive group (n=61) stable (n=58) based on re-examination computed tomography...
Current management of small cell lung cancer (SCLC) remains challenging. Effective biomarkers are needed to subdivide patients presenting distinct treatment response and clinical outcomes. An understanding heterogeneous phenotypes aneuploid CD31- circulating tumor cells (CTCs) CD31+ endothelial (CTECs) may provide novel insights in the SCLC. In present translational prospective study, increased metastasis-related proliferation motility, accompanied with up-regulated mesenchymal marker...
The high carbon emissions of vehicles traveling on horizontal curve road sections cannot be ignored. Facing the difficulty accurately quantifying emission driving curves and unknown causes emission, this study proposes to construct a prediction model applicable with different planar geometries. direct indirect effects alignment vehicle are represented in terms travel stabilization speed changes, respectively. A lateral force coefficient parameter was introduced into integrate quantification...
Venous thromboembolism (VTE) is an insidious disease with significant morbidity and mortality. We conducted a retrospective single-center study on patients who underwent thoracic surgery developed novel VTE risk assessment model (RAM).Patients between July 2016 December 2017 (n=533) at the Beijing Chao-Yang Hospital were enrolled in this study. None of received any prophylaxis perioperatively. Lower limbs Doppler ultrasonography was performed before after for deep venous thrombosis (DVT)...
Introduction: Despite surgical and chemotherapeutical treatment options, the prognosis for glioblastoma (GBM) remains poor. Some studies have found that using lomustine plus bevacizumab to treat GBM can prolong overall survival (OS) progression-free (PFS). The aim of this study was explore efficacy two drugs in combination a meta-analysis existing literature help settle ongoing debate. Materials Methods: PubMed, EMBASE, Cochrane Library were searched effectiveness literature, updated on June...
Background The objective of this study was to describe the clinical presentation and outcomes human papillomavirus (HPV)‐positive nasopharyngeal cancer (NPC) versus Epstein–Barr virus (EBV)‐positive NPC HPV‐positive oropharyngeal (OPC). Methods Clinical characteristics presenting signs/symptoms were compared between patients who had viral‐related OPC treated with intensity‐modulated radiotherapy from 2005 2020 matched 1:1 (by tumor lymph node categories, smoking, age, sex, histology, year...
Abstract Background The causes for delays during the COVID19 pandemic and their impact on head neck cancer (HNC) diagnosis staging are not well described. Methods Two cohorts were defined a priori review analysis—a Pre‐Pandemic cohort (June 1 to December 31, 2019) Pandemic 2020). Delays categorized as COVID‐19 related or not, clinician, patient, policy related. Results A total of 638 HNC patients identified including 327 in Cohort 311 Cohort. Patients had more N2‐N3 category (41% vs. 33%, p...