A5089618971- Ion-surface interactions and analysis
- Nuclear Physics and Applications
- X-ray Spectroscopy and Fluorescence Analysis
- Nuclear materials and radiation effects
- Asymmetric Hydrogenation and Catalysis
- Radiation Detection and Scintillator Technologies
- Catalytic C–H Functionalization Methods
- Integrated Circuits and Semiconductor Failure Analysis
- Photorefractive and Nonlinear Optics
- Synthesis and Catalytic Reactions
- Plant Genetic and Mutation Studies
- Carbon dioxide utilization in catalysis
- High-pressure geophysics and materials
- Glass properties and applications
- Catalysis for Biomass Conversion
- Asymmetric Synthesis and Catalysis
- Chemical Synthesis and Reactions
- Nanomaterials for catalytic reactions
- Electron and X-Ray Spectroscopy Techniques
- Radiation Shielding Materials Analysis
- Fusion materials and technologies
- Synthetic Organic Chemistry Methods
- Silicon and Solar Cell Technologies
- GABA and Rice Research
- Chemical Synthesis and Analysis
Xihua University
2025
Shandong University
1996-2024
Tongji University
2020
Peking University
2018-2020
University of Wisconsin–Madison
2015-2019
Beijing University of Chemical Technology
2018
State Key Laboratory of Chemical Engineering
2018
Madison Group (United States)
2016-2017
Tianjin University
2014-2015
Collaborative Innovation Center of Chemical Science and Engineering Tianjin
2014
The construction of N-heterocyclic eight-membered rings with good regio-, stereo-, and enantioselective control remains a formidable challenge in asymmetric catalysis. Herein, we report palladium-catalyzed [4 + 4] cycloaddition anthranils γ-methylidene-δ-valerolactones the presence Et3B, delivering highly functionalized tetrahydrobenzo[b]azocine derivatives high efficiency diastereoselectivities enantioselectivities (up to 92% yield, 20:1 dr, 99% ee). Moreover, complex substrates derived...
Idiopathic pulmonary fibrosis (IPF), a lethal respiratory disease with few treatment options, occurs due to repetitive microinjuries alveolar epithelial cells (AECs) and progresses an overwhelming deposition of extracellular matrix (ECM), ultimately resulting in fibrotic scars destroyed the architecture. Here, inhaled ribosomal protein-based mRNA nanoformulation is reported for clearing intrapulmonary ECM re-epithelializing disrupted epithelium, thereby reversing established foci IPF. The...
A highly efficient iridium catalyst is developed for the chemoselective reduction of aldehydes to alcohols in water, using formic acid as a reductant.
Simple and functionalized ketones are readily reduced in water with very low catalyst loading using formic acid as a hydride donor.
Abstract The electrocatalytic coupling of the nitrate reduction reaction (NO 3 − RR) and hydrazine oxidation (HzOR), denoted as NO RR||HzOR, not only holds promise for synthesis high‐value‐added products (such NH ) but also facilitates bidirectional nitrogen neutralization. Here, sponge‐like porous nitrogen‐doped carbon encapsulated Cu nanoparticles electrocatalysts is presented electrochemical RR||HzOR. Substituting traditional oxygen evolution (OER) with HzOR anode notably accelerates...
A highly π-facial selective and regioselective fluorination of chiral enamides is described. The reaction involves an enantioselective exclusively at the electron-rich enamide olefin with N-F reagents such as Selectfluor N-fluoro-benzenesulfonimide [NFSI] accompanied by trapping β-fluoro-iminium cationic intermediate water. resulting N,O-hemiacetal could be oxidized using Dess-Martin periodinane, leading to asymmetric sequence for syntheses α-fluoro-imides optically enriched α-fluoro-ketones.
The pH-dependent selective Ir-catalyzed hydrogenation of α,β-unsaturated aldehydes was realized in water. Using HCOOH as the hydride donor at low pH, unsaturated alcohol products were obtained exclusively, while saturated formed preferentially by employing HCOONa high pH. A wide range functional groups including electron-rich well electron-poor substituents on aryl group can be tolerated, affording corresponding excellent yields with TOF values. High selectivity and also observed for...
An efficient chemoselective iridium-catalyzed method for the hydroxylation and alkoxylation of organosilanes to generate hydrogen gas silanols or silyl ethers was developed. A variety sterically hindered silanes with alkyl, aryl, ether groups were tolerated. Furthermore, this atom-economical catalytic protocol can be used synthesis silanediols silanetriols. one-pot silane oxidation reduction aldehydes/ketones also realized.
We have developed a versatile synthetic strategy for the synthesis of natural product diptoindonesin G and its analogues as selective modulators estrogen receptors.
An efficient palladium-catalyzed asymmetric [4 + 4] cycloaddition of highly reactive ortho -quinone methides with γ-methylidene-δ-valerolactones for the construction functionalized eight-membered benzo[ b ]oxocine derivatives has been developed.
x-membered lactams were synthesized via either an amidation of sp3 C–H bonds or electrophilic substitution arenes Ir-nitrene intermediates. With the employment a readily available iridium catalyst in dichloromethane hexafluoro-2-propanol, wide range good to excellent yields with high selectivity.
Abstract Palladium-catalyzed decarboxylative asymmetric allylic alkylation (DAAA) provides an efficient and powerful strategy to construct quaternary stereocenters, which are widely present in biologically active natural products approved drugs. In this short review, we summarize recent developments (since 2018) the facile synthesis of stereocenters via DAAA methods. Several representative examples use strategies for total complex further demonstrate its synthetic potential realm organic...
A concise, stereoselective, and protecting-group-free total synthesis of aplykurodinone-1 from Hajos-Parrish ketone was described. The synthetic approach features a sequence aerobic allylic oxidation elimination alcohol 9. key intermediate for this formed by stereoselective intramolecular radical cyclization.
This paper presents a novel and environment‐friendly process for the dehydration of carbohydrates to ethoxymethylfurfural (EMF) levulinic acid ethyl ester (LAEE) under catalysis DMSO/H2SO4. The catalyst was recycled efficiently easily over seven times without any significant loss in fructose conversion. For conversion inulin, EMF LAEE were obtained 83% 80% total yields, respectively. effects loading, reaction temperature, time on investigated.
Abstract We recently developed a novel chiral catalyst‐directed dynamic kinetic diastereoselective acylation of hemiacetals for the synthesis carbohydrates. In this update, we describe catalytic method enantioselective 2‐chromanols using benzotetramisole derived catalysts. High yields and enantiomeric excesses were obtained broad range acylated 2‐chromanols, which are important intermediates various bioactive pharmaceuticals. hypothesize that high stereoselectivity reaction originates from...
A novel asymmetric [3 + 2] cycloaddition reaction of 1,4-dipoles and nitroolefins catalysed by the cooperative action chiral palladium/phosphine complex urea-tertiary amine is described.
The range profile of Hg+ implanted at energies from 50 to 400 keV in glass was measured by 4He+ Rutherford backscattering. projected ranges are good agreement with those predicted the Biersack model. A marked improvement straggling fit is obtained after considering second-order energy loss.
A practical and efficient method for the synthesis of alcohols in one pot from readily available alkynes via a tandem process by formic acid promoted hydration metal-ligand bifunctional iridium-catalyzed transfer hydrogenation under mild conditions has been described. This transformation is simple, efficient, can be performed with variety good yields excellent stereoselectivities. Experimental results showed high catalytic activity, turnover frequency (TOF) up to 25000. Importantly, this...
The optical waveguide was formed on an LiNbO3 substrate by 2.6 MeV nickel ions implantation to the dose of 9×1014 ions/cm2. Five dark modes were observed prism coupling technique. refractive index profile obtained using reflectivity calculation method. A large decrease found in guiding region and barrier, which is somewhat different from that He+ ions. position barrier deeper than damage peak calculated TRIM'90 (Transport Ions Matter) code. crystal lattice caused Ni+ ion analysed Rutherford...