A5103019592- Orthopedic Surgery and Rehabilitation
- Nutrition and Health in Aging
- Rheumatoid Arthritis Research and Therapies
- Elbow and Forearm Trauma Treatment
- Bone fractures and treatments
- Autoimmune and Inflammatory Disorders Research
- Pharmacy and Medical Practices
- Spinal Fractures and Fixation Techniques
- Safe Handling of Antineoplastic Drugs
- Scoliosis diagnosis and treatment
- Body Composition Measurement Techniques
- Pharmaceutical studies and practices
- Congenital limb and hand anomalies
- Shoulder Injury and Treatment
- Chronic Disease Management Strategies
- Pharmaceutical Practices and Patient Outcomes
- Cerebral Palsy and Movement Disorders
- Spine and Intervertebral Disc Pathology
- Neuroscience and Neuropharmacology Research
- Orthopedic Infections and Treatments
- Electroconvulsive Therapy Studies
- Orthopaedic implants and arthroplasty
- Cancer Immunotherapy and Biomarkers
- Knee injuries and reconstruction techniques
- Pharmacological Effects and Toxicity Studies
Ehime University Hospital
2010-2024
Osaka City General Hospital
2009-2024
Ehime University
2009-2024
Ibero American University
2019
Texas A&M University
2018
Shujitsu University
2018
Smith College
2018
Syracuse University
2018
University of Memphis
2018
Louisiana State University Health Sciences Center New Orleans
2018
Aim Frailty is defined as the degradation of physical and cognitive function in older adults. The relationship between frailty disease activity patients with rheumatoid arthritis unclear. Factors related to Japanese were investigated a cross‐sectional analysis. Methods Of 100 who entered prospective, observational Correlation research sarcopenia, skeletal muscle (CHIKARA) study, 95 completed check list (maximal score 25), classified frail (8–25 points), pre‐frail (4–7 points) normal (0–3...
We previously showed that inhibition of repeated electroconvulsive shock (ECS)-induced seizures through 7-day administration anti-epileptic drugs suppressed the impairment spontaneous alternation behavior in Y-maze test rats. To clarify precise mechanism(s), we investigated effect valproate on such and examined levels brain-derived neurotrophic factor (BDNF) c-Fos protein prefrontal cortex hippocampus 24h after last ECS. Seven-day intraperitoneal (i.p.) (400mg/kg) behavior. Repeated ECS...
Retrospective comparative study.To compare the incidence of proximal junctional kyphosis (PJK) between transverse process hooks (TPHs) and pedicle screws (PSs) at upper instrumented vertebrae (UIV) following adult spinal deformity (ASD) surgery.The choice UIV implant type may be important for avoiding PJK; however, few clinical studies have evaluated PJK according to used in ASD surgery.We retrospectively reviewed 39 consecutive patients with (mean age, 67 years; mean follow-up period, 41...
Abstract Aim Patients with rheumatoid arthritis ( RA ) show lower muscle mass and a higher prevalence of sarcopenia than healthy individuals. Correlations between disease activity, physical function, laboratory data body composition at baseline were investigated in prospective, observational study CHIKARA study) patients. Methods Body was measured using bioelectrical impedance analyzer. Parameters compared non‐sarcopenia groups, correlations Disease Activity Score 28 joints – erythrocyte...
The navigation system was introduced to orthopaedic surgery in the 1990s. More recently, CT-based systems have been used more commonly spine and joint replacement because of their precision.The aim our study evaluate accuracy efficacy navigation-assisted excision bone soft tissue tumors.From 2006 2009, we performed 16 patients, 11 males five females, with a mean age 39 years (range, 13-70 years). We diagnosed nine benign tumors seven malignant tumors. In two infiltrated adjacent bones. Nine...
The purpose of this study was to assess the clinical results posterior corrective surgery using a multilevel transforaminal lumbar interbody fusion (TLIF) with rod rotation (RR) and evaluate segmental effect TLIF CT imaging. medical records 15 consecutive patients degenerative kyphoscoliosis (DLKS) who had undergone spinal an RR technique minimum follow-up 2 years were retrospectively reviewed. Radiographic parameters evaluated plain radiographs, correction Clinical outcomes Scoliosis...
A retrospective case control study.The purpose of this study was to compare the surgical outcomes multilevel lateral lumbar interbody fusion (LIF) and posterior (PLIF) in treatment adult spinal deformity (ASD) evaluate sagittal plane correction by combining LIF with posterior-column osteotomy (PCO).The between PLIF ASD patients remain unclear.We retrospectively reviewed 31 who underwent combined PCO (LIF group, n=14) or (PLIF n=17) a minimum 2-year follow-up. In comparison groups, their mean...
Epileptic patients are at a significantly higher risk for impairments of cognitive function and behavioral abnormalities. In this study, we investigated the effect repeated electroconvulsive shock (ECS)-induced seizures on spontaneous alternation behavior in Y-maze test locomotor activity an open-field test, examined effects anti-epileptic drugs rats. ECS was administered seven consecutive days tests were performed 24 h after last administration. The impaired increased activity. Moreover,...
The object of this study was to analyze the prevalence postoperative coronal imbalance (CIB) and related factors in patients with adult lumbar scoliosis.
Patients with rheumatoid arthritis (RA) have a higher risk of falls and fractures due to muscle weakness painful joints the lower extremities. Evaluation functions is important predict fractures. The aim was investigate relationships in RA patients.Stand-up power, speed, stabilizing time were evaluated by function analyzer 90 patients CHIKARA study (UMIN000023744). falls, fractures, body composition, Disease Activity Score 28 - erythrocyte sedimentation rate (DAS28-ESR), modified Health...
Paroxetine is often coadministered with low-dose aspirin to treat cerebral infarction patients depression. In order assess the ulcerogenic risk induced by coadministration of these drugs, we examined their effects on gastric secretion using pylorus ligation method and determined prostaglandin E2 (PGE2) content in mucosa enzyme immunoassay (EIA). stimulated fluid acid output, dose-dependently, however, it had no effect PGE2 mucosa. Furthermore, exogenous serotonin inhibited both output. The...
Abstract Aging influences peripheral nerve regeneration. Nevertheless, most basic research of bioabsorbable conduits including commercial products have been performed in very young animals. Results from these studies may not provide information about axonal regeneration aged tissue, because tissue holds sufficient endogenous potential for The clinical target age conduit application is likely going to increase with a rapidly growing elderly population. In the present study, we examined after...
Sarcopenia is relatively common in rheumatoid arthritis (RA) patients. Thicknesses of the quadriceps muscle and fat are easily measured by ultrasound (US) known to be related skeletal mass mass, respectively.Eighty-four patients enrolled prospective correlation research sarcopenia, muscle, disease activity study (UMIN000023744) underwent US examinations anterior thigh thickness (MT) (FT). Muscle body (BF) were also examined a composition analyzer. Whether MT FT sarcopenia obesity was...
Abstract Occupational exposure of anticancer agents during their preparation has been recognized as a serious hazard. Closed system drug transfer devices (CSTDs) enable “safe” for medical personnel and ensure safe hospital environment. However, artificial particles infusion materials have reported CSTD use. Here, the incidence insoluble fine using CSTDs was examined. Visible were found in 465 (9.4%) 4948 treatment cases at Ehime University Hospital with Contaminants occurred more frequently...
Background: Multiple treatment protocols have been described in literature for the of terrible triad injury (TTI) elbow. We believe that repair medial collateral ligament (MCL) should be performed preference to a small coronoid fracture if elbow is unstable after fixation/replacement radial head and lateral (LCL). The aim this study report outcomes surgical patients with TTI associated whom was not addressed. Methods: This retrospective case series 12 consecutive who underwent surgery acute...
A chronic traumatic hyperextension of the proximal interphalangeal (PIP) joint can result from volar plate (VP) disruption. For treatment this disorder, reconstruction procedures have been traditionally recommended, because condition VP was not considered susceptible to repair due retraction or attenuation. The purpose paper is present operative technique and report clinical results late repair. Late performed for chronic, post-traumatic deformity PIP little finger resulting disruption in...
Abstract Introduction The effects of biologic and targeted synthetic disease‐modifying anti‐rheumatic drugs (b/tsDMARDs) conventional (csDMARDs) on body composition muscle function in rheumatoid arthritis (RA) patients requiring treatment enhancement were compared. Methods This multicenter, prospective, observational study (PRESENT Study) divided RA non‐randomly into a csDMARD group ( n = 100) b/tsDMARD 100). Changes examined 80 each followed for 52 weeks. percentages new‐onset improved...