A5101928519- Ovarian cancer diagnosis and treatment
- Thyroid Cancer Diagnosis and Treatment
- Polyomavirus and related diseases
- Cancer Cells and Metastasis
- Radiomics and Machine Learning in Medical Imaging
- Endometrial and Cervical Cancer Treatments
- Cancer, Lipids, and Metabolism
- Genetic factors in colorectal cancer
- Inflammatory Biomarkers in Disease Prognosis
- Cancer Mechanisms and Therapy
- Cardiac tumors and thrombi
- Intraperitoneal and Appendiceal Malignancies
- Lymphoma Diagnosis and Treatment
- Chemotherapy-induced cardiotoxicity and mitigation
- Thermal Regulation in Medicine
- Hepatocellular Carcinoma Treatment and Prognosis
- Brain Metastases and Treatment
- Cervical Cancer and HPV Research
- Vascular Tumors and Angiosarcomas
- Cancer-related Molecular Pathways
- Peptidase Inhibition and Analysis
- Cancer-related molecular mechanisms research
- Frailty in Older Adults
- Vector-Borne Animal Diseases
- Eosinophilic Disorders and Syndromes
Hengshui University
2025
Soochow University
2008-2024
First Affiliated Hospital of Soochow University
2008-2024
Fudan University Shanghai Cancer Center
2010-2024
Shanghai Medical College of Fudan University
2010-2024
Zhongda Hospital Southeast University
2024
State Key Laboratory of Genetic Engineering
2016
Fudan University
2016
Southwest Hospital
2013-2014
Southwest General Health Center
2014
Abstract Objective The International Federation of Gynecology and Obstetrics (FIGO) 2023 staging system for endometrial cancer (EC) was released with incorporating histology, lympho-vascular space invasion, molecular classification together. Our objective is to further explore the clinical utility prognostic significance FIGO in China. Methods A retrospective analysis conducted patients who received standard surgeries underwent genetic testing using multigene next-generation sequencing (NGS)...
Objective To explore the risk factors for cardiotoxicity in patients with gastrointestinal (GI) tumors treated fluorouracil drugs. Methods This study included GI who received at our hospital between January 2018 and April 2022. The demographic clinical characteristics were collected. associated of explored using multivariable logistic regression. Results A total 300 finally divided into ( n = 81) non-cardiotoxicity groups 219). occurrence fluorouracil-induced was higher hypertension,...
The epithelial-to-mesenchymal transition (EMT) status is associated with programmed death-1 ligand 1 (PD-L1) expression in various cancers. However, the role and molecular mechanism of PD-L1 EMT sorafenib-resistant hepatocellular carcinoma (HCC) cells remain elusive. In this study, we aimed to investigate regulation on HCC cells. Initially, cell lines HepG2 SR Huh7 were established. Western-blot assays used detect PD-L1, E-cadherin, N-cadherin. intervention overexpression explore Cell...
Aberrant expression of Retinoic acid receptor γ (RARγ) is implicated in cancer development. Our previous study identified that RARγ functions as a tumor promoter to drive hepatocellular carcinoma (HCC) growth. However, its contribution HCC invasion and metastasis remains unclear. clinical samples was detected by western blot immunohistochemistry. The relationship between levels the characteristics were evaluated. cell line MHCC-97H stably knocked down using lentivirus vector-based shRNA...
ABSTRACT Background Cancer cachexia can impact prognosis, cause resistance to anticancer treatments and affect the tolerability of treatments. This study aims identify hepatocellular carcinoma (HCC) with by characterizing longitudinal body composition ( BC ) trajectories. Methods longitudinal, multicentre cohort included unresectable HCC patients treated first‐line programmed death‐(ligand)1 inhibitors plus anti‐vascular endothelial growth factor antibody/tyrosine kinase between...
There exists no universally accepted treatment for primary thyroid non-Hodgkin's lymphoma (TNHL) due to the rarity of this entity. The aim study is assess role surgery and explore prognostic factors in Chinese TNHL patients.Patient presentations, pathologies, surgical interventions, multidisciplinary treatment, value fine needle aspiration were analyzed.Between 1991 2007, 40 patients diagnosed. Thirty-eight underwent an initial procedure. Further treatments consisted radiotherapy or...
Objectives: To investigate the predictive value of inflammatory biomarkers in patients with unresectable hepatocellular carcinoma (HCC) for outcomes following combination treatment transarterial chemoembolization (TACE) plus sorafenib. Materials and Methods: A total 314 (270 male 44 female) treatment-naïve HCC treated by TACE sorafenib between January 2011 December 2018 were enrolled retrospective study. The primary outcome was overall survival (OS). secondary progression-free (PFS)....
The rearranged during transfection (RET) proto-oncogene fusion is common in papillary thyroid cancer (PTC), varying across ethnic groups. However, comprehensive comparisons of RET types are limited. This study aims to identify predominant fusions and analyze their clinicopathological characteristics a cohort Chinese cases.
This study aimed to assess the correlation of katanin P60 expression with clinical characteristics and survival profiles surgical non-small cell lung cancer (NSCLC) patients.Two hundred sixty-five primary NSCLC patients treated by resection were retrospectively viewed. The in tumor specimen was detected immunohistochemical (IHC) staining assay. Preoperative data collected from patients' medical records, extracted follow-up records.There 127 (47.9%) 138 (52.1%) P60-low -high expression,...
Objective To investigate the efficacy and safety of optimal alkalized hydration solution for hemorrhagic cystitis (HC) following unrelated donor allogeneic hematopoietic stem cell transplantation (URD-HSCT), risk factors prophylaxis measures about HC.Methods The clinical data 151 HC patients who underwent URD-HSCT were retrospectively analyzed. All given busulfan/cyclophosphamide (BuCy)-based conditioning regimen.During Cy therapy, all to prevent HC.MESNA was intravenously after...