Dementia is a major concern among growing chronic diseases in the aging society and its association with polypharmacy has not been adequately assessed. The objective of this study was to determine between dementia through multiple statistical approaches. We conducted nested case-control for newly diagnosed cases using South Korean National Health Insurance Service sample cohort database (2002–2013, n = 1,025,340). Interactions (an average use ≥5 prescription drugs daily) comorbidities or...

The present study evaluated the associations of fat-to-muscle ratio (FMR) with metabolic syndrome (MetS) and insulin resistance (IR) in Korean adults using nationally representative survey data.A two-stage stratified sampling method was reflected a cross-sectional involving total 13 032 participants aged ≥ 19 years who participated fourth fifth Korea National Health Nutrition Examination Surveys. homeostasis model assessment for IR (HOMA-IR) used to evaluate calculated as follows: [fasting...

Abstract Background Body composition changes with ageing can influence the adiponectin concentration. However, component of body that is associated concentrations in older adults remains unclear. Methods There were 152 males and 168 females aged 65 years or participated 2010 Hallym Aging Study (HAS). (assessed by dual energy X-ray absorptiometry; DXA), anthropometric parameters obtained from all participants. Multivariate linear regression models assessed association fat percentage, regional...

ABSTRACT Limited head-to-head comparative safety and effectiveness data exist between denosumab zoledronic acid in real-world healthcare. We aimed to examine the of compared with regard risk serious infection cardiovascular disease (CVD) osteoporotic fracture. conducted a cohort study using claims (2009–2013) from US commercial insurance plan database. included patients aged ≥50 years who were newly initiated on or acid. The primary outcomes (1) hospitalization for infection; (2) composite...

Previous studies reported mixed results regarding the association between cognition and body weight in late life. We evaluated relationships cognitive function composition among community-dwelling older adults.Three hundred twenty subjects (≥65 years, women 53%) with available data of from 2010 Hallym Aging Study. Cognitive was assessed using Korean Mini-Mental State Examination (K-MMSE). Dual-energy X-ray absorptiometry (DEXA) used for measuring including fat lean mass. Anthropometric...

The coronavirus disease pandemic is predicted to have adverse health effects on children and adolescents who are overweight or obese due restricted school activity stay-at-home orders. purpose of this observational study was determine the factors associated with weight gain in obesity during 2019 (COVID-19) lockdown.Ninety-seven participants (sex- age-specific body mass index (BMI) ≥ 85th percentile) were included. A baseline examination conducted pre-COVID-19 (August January 2020),...

The increasing prevalence of childhood obesity is a serious public health problem associated with co-morbidities in adulthood, as well childhood. This study was conducted to identify associations between total sugar intake and from different foods (fruit, milk, sugar-sweetened beverages (SSBs)), adiposity continuous metabolic syndrome scores (cMetS) among Korean children adolescents using cohort data. subjects were (n = 770) who participated the 4th year (2008) Child-Adolescent Cohort Study...

The aim of this study was to investigate the association between hypertension and kimchi, a salt-fermented vegetable, intake. This based on data from Korea National Health Nutrition Examination Survey conducted in 2007, 2008, 2009, 2010, 2011, 2012. In final analysis, total 20,114 Korean adults (men = 7,815, women 12,299) included. Daily energy, nutrient, kimchi intake were assessed using 24-hour dietary recall. odds ratios for hypertension, according groups quintiles consumption by gender,...

Objectives To evaluate the association between fracture risk and levothyroxine use in elderly women with hypothyroidism, according to previous osteoporosis history. Methods We conducted a cohort study from Korean Health Insurance Review Assessment Service claims database January 2005 June 2006. The population comprised aged ≥65 years who had been diagnosed hypothyroidism prescribed monotherapy. excluded patients met any of following criteria: history, hyperthyroidism, thyroid cancer, or...

Overweight and obesity have become a global epidemic they may impair health. Traditional use growing evidence indicate that mate (Ilex paraguariensis A. St.-Hil.) be helpful in losing excessive weight fat. The present randomized, double-blind, placebo-controlled study evaluated efficacy safety of an extract from green 60 overweight subjects aged 20–39 years during 6-weeks. Body composition was measured by Dual-Energy X-ray Absorptiometry (DEXA) at baseline after 6 weeks. weight, body mass...

Galectin-3 levels have been studied as a potential biomarker for predicting cardiovascular (CV) risk and mortality in hemodialysis (HD) patients. Recently, close relationship between galectin-3 vascular calcification (VC) has reported. Here, we investigated the role of VC mediating factor association mortality. Serum baseline aortic arch (AoAC) score were measured 477 incident HD Mortality data obtained at median follow-up 40 months. Causal mediation analysis was performed to examine effect...

Abstract The relationship between body weight changes in late life and cognitive function is controversial. We investigated whether gain or loss affected community-dwelling older adults over a 3-year period. Our study used data from the Survey of Living Conditions Welfare Needs Korean Older Persons included 3859 subjects (aged ≥65 years) with normal cognition at baseline. At baseline follow-up, height were measured, was assessed using mini-mental state examination. Based on their mass index...

Background: Obesity is commonly assessed by body mass index (BMI) of which limitations come from an inability to distinguish fat lean mass. Several anthropometric measurements, including BMI, waist circumference, waist-to-height ratio and waist-to-hip have been used predict metabolic syndrome. The purpose this study was evaluate the utility FMI or BF% combined with previous known indices assess risk syndrome in clinical practice. Methods: In 5534 men visiting a hospital for health check-ups,...

The aim of this study was to investigate the causal relationship between high consumption salt-fermented vegetables and hypertension risk in adults.Data came from Korean Genome Epidemiology Study, an ongoing community-based cohort that began 2001. In final analysis, a total 5,932 participants (men=2,822, women=3,110) included. Daily energy, nutrient, major for (kimchi) intakes were assessed using semi-quantitative food frequency questionnaire. Relative risks 95% CIs associated with kimchi...

This study aimed to evaluate the differences of prescribing pattern between bisphosphonate and raloxifene users among Korean women with osteoporosis, focusing on underlying conditions, concurrent medications, nature healthcare utilization, regional disparity. We used Health Insurance Review Assessment Service National Patients Sample database year 2010. Study subjects were defined as female osteoporosis patients aged over 50 years both diagnosis prescriptions or raloxifene. The frequency...