A5028928025- Cancer Research and Treatments
- Ubiquitin and proteasome pathways
- Plant-Microbe Interactions and Immunity
- Plant Stress Responses and Tolerance
- Molecular Biology Techniques and Applications
- Plant responses to water stress
- Peptidase Inhibition and Analysis
- Autophagy in Disease and Therapy
- Plant Pathogens and Resistance
- Plant Reproductive Biology
- Antimicrobial Peptides and Activities
- Biopolymer Synthesis and Applications
- Plant Micronutrient Interactions and Effects
- Genetic Mapping and Diversity in Plants and Animals
- Forensic and Genetic Research
- Chromatin Remodeling and Cancer
- Tissue Engineering and Regenerative Medicine
- Protein Degradation and Inhibitors
- Bone health and treatments
- Plant biochemistry and biosynthesis
- Cancer-related molecular mechanisms research
- Genetics and Physical Performance
- Cancer, Hypoxia, and Metabolism
- Cancer-related gene regulation
- Legume Nitrogen Fixing Symbiosis
Swedish University of Agricultural Sciences
2024
University of Zurich
2021-2023
Institute of Genetics and Developmental Biology
2015-2018
Center for Excellence in Molecular Plant Sciences
2017-2018
Chinese Academy of Sciences
2015-2018
University of Chinese Academy of Sciences
2015-2018
State Key Laboratory of Plant Genomics
2015-2018
The Barbara Ann Karmanos Cancer Institute
2010
Wayne State University
2010
Harbin Medical University
1999-2003
Nitric oxide (NO) and reactive oxygen species (ROS) are two classes of key signaling molecules involved in various developmental processes stress responses plants. The burst NO ROS triggered by stimuli activates downstream pathways to cope with abiotic biotic stresses. Emerging evidence suggests that the interplay plays a critical role regulating responses. However, underpinning molecular mechanism remains poorly understood. Here, we show positively regulates activity Arabidopsis...
Plant genomes encode hundreds of receptor kinases and peptides, but the number known plant receptor-ligand pairs is limited. We report that Arabidopsis leucine-rich repeat kinase LRR-RK MALE DISCOVERER 1-INTERACTING RECEPTOR LIKE KINASE 2 (MIK2) for SERINE RICH ENDOGENOUS PEPTIDE (SCOOP) phytocytokines. MIK2 necessary sufficient immune responses triggered by multiple SCOOP suggesting this divergent family peptides. Accordingly, SCOOP12 peptide directly binds triggers complex formation...
Abstract Continued climate change impose multiple stressors on crops, including pathogens, salt, and drought, severely impacting agricultural productivity. Innovative solutions are necessary to develop resilient crops. Here, using quantitative potato proteomics, we identify Parakletos, a thylakoid protein that contributes disease susceptibility. We show knockout or silencing of Parakletos enhances resistance oomycete, fungi, bacteria, whereas its overexpression reduces resistance. In...
Abstract Thoracic malignancies and human breast cancers (HBC) continue to be aggressive solid tumors that are poor responders the existing chemotherapeutic approaches. Malignant Pleural Mesothelioma (MPM) is an asbestos-related tumor of thoracic pleura lacks effective treatment options. Altered ubiquitin proteasome pathway frequently encountered in many including HBC MPM thus serves as important target for therapeutic intervention strategies. Although inhibitor Velcade (Bortezomib) has been...
The allelic states of DYS199 locus were studied by allele-specific PCR. We found that all the 107 samples chosen from three populations northeast China had C alleles. result excluded possibility this mutation first identified in native American came China.