A5115695496- Ruminant Nutrition and Digestive Physiology
- Reproductive Physiology in Livestock
- Genetic and phenotypic traits in livestock
- Gut microbiota and health
- Effects of Environmental Stressors on Livestock
- Animal health and immunology
- Extracellular vesicles in disease
- Probiotics and Fermented Foods
- Turfgrass Adaptation and Management
- Clostridium difficile and Clostridium perfringens research
- Cancer-related molecular mechanisms research
- Viral gastroenteritis research and epidemiology
- Plant and fungal interactions
- MicroRNA in disease regulation
- Meat and Animal Product Quality
- Selenium in Biological Systems
- Metabolomics and Mass Spectrometry Studies
- Autophagy in Disease and Therapy
- Inflammasome and immune disorders
- Soil Carbon and Nitrogen Dynamics
- Protein Hydrolysis and Bioactive Peptides
- Agriculture and Farm Safety
- Circular RNAs in diseases
- Immune Cell Function and Interaction
- Moringa oleifera research and applications
China Agricultural University
2016-2025
Hunan University of Traditional Chinese Medicine
2025
Affiliated Hospital of Hebei University
2025
Shanxi Academy of Medical Sciences
2021-2024
State Key Laboratory of Animal Nutrition
2016-2024
Hebei Academy of Agriculture and Forestry Sciences
2024
China Pharmaceutical University
2013-2024
Shanxi Medical University
2021-2024
Hunan Agricultural University
2024
University of Chinese Academy of Sciences
2024
Nitrous oxide (N2 O) is a greenhouse gas that also plays the primary role in stratospheric ozone depletion. The use of nitrogen fertilizers known as major reason for atmospheric N2 O increase. Empirical bottom-up models therefore estimate agricultural inventories using N loading sole predictor, disregarding regional heterogeneities soil inherent response to external loading. Several environmental factors have been found influence emission fertilization, but their interdependence and relative...
Abstract Background Antimicrobials are often used to prevent and treat diarrhea induced by enteroaggregative Escherichia coli (EAEC) in young ruminants. However, drug overuse or misuse accelerates the spread of multidrug-resistant extended-spectrum β-lactamase (ESBL)-producing E. . Thus, supplementary foods as alternatives antibiotics needed colibacillus neonatal dairy calves. Ursodeoxycholic acid (UDCA), a therapeutic bile acid, helps alleviate colitis. how UDCA ESBL-EAEC-induced clinical...
Aging is regulated by conserved signaling pathways. The glycogen synthase kinase-3 (GSK-3) family of serine/threonine kinases regulates several these pathways, but the role GSK-3 in aging unknown. Herein, we demonstrate premature death and acceleration age-related pathologies Gsk3a global KO mouse. mice developed cardiac hypertrophy contractile dysfunction as well sarcomere disruption striking sarcopenia skeletal muscle, a classical finding aging. We also observed severe vacuolar...
A better understanding of global ruminal microbiota and metabolites under extensive feeding conditions is a prerequisite for optimizing rumen function improving ruminant feed efficiency. Furthermore, the gap between information on needs to be bridged. The aim this study was investigate effects wide range forage concentrate ratios (F:C) changes interactions metabolites. Four diets with different F:C (80:20, 60:40, 40:60, 20:80) were limit-fed 24 Holstein heifers, Illumina MiSeq sequencing gas...
Background: Diabetes mellitus exacerbates myocardial ischemia/reperfusion (MI/R) injury by incompletely understood mechanisms. Adipocyte dysfunction contributes to remote organ injury. However, the molecular mechanisms linking dysfunctional adipocytes increased MI/R remain unidentified. The current study attempted clarify whether and how small extracellular vesicles (sEV) may mediate pathological communication between diabetic cardiomyocytes, exacerbating Methods: Adult male mice were fed a...
Abstract Background Primary Sjögren's syndrome (pSS) is an autoimmune disease that leads to the destruction of exocrine glands and multisystem lesions. Abnormal proliferation, apoptosis, differentiation CD4 + T cells are key factors in pathogenesis pSS. Autophagy one important mechanisms maintain immune homeostasis function cells. Human umbilical cord mesenchymal stem cell-derived exosomes (UCMSC-Exos) may simulate immunoregulation MSCs while avoiding risks treatment. However, whether...
Paper mulberry (Broussonetia papyrifera; PM) is an excellent and extensive type of roughage in Asia. This study aimed to evaluate the effects PM silage on milk production, apparent digestibility, antioxidant capacity, fecal bacteria composition Holstein dairy cows. Forty-five lactating cows with a similar yield parity were selected randomly assigned three groups. The control group was fed non-PM diet, PM-treated groups 4.5 9.0% supplementary diets for 28 days. Then, treatment containing 13.5...
The rates of mortality and involuntary culling dairy calves replacement heifers have great economic implications on the cattle industry around world. main objectives this study were: (1) to obtain population parameters heifers; and, (2) investigate factors affecting in Chinese Holstein cattle. Two datasets containing records birth, calving, events from 142,833 born between 1991 2018 were used study. obtained using dataset 1, which consisted that died or involuntarily culled. Three survival...
Abstract In this study, we examined differences between the microbiota of ruminal fluid (DR) and feces (DF) from five lactating dairy cows over three consecutive days using 16S rRNA gene sequence‐based analysis. Results showed significant microbial communities DR DF. particular, relative abundance phyla Firmicutes Actinobacteria was significantly lower ( q < 0.001) in compared with DF, while Bacteroidetes higher DF than that 0.001). A genera Bifidobacterium , 5‐7N15 Clostridium...
Abstract Long‐term artificial selection and environmental shifts have driven adaptive changes in both the host genome intestinal microbiota. The complex symbiotic relationship between these two has become essential for maintaining homeostasis overall health. Concurrently, advancements sequencing technology functional annotation of noncoding RNAs, particularly microRNAs (miRNAs), facilitated exploration mechanisms regulating homeostasis. Herein, we systematically update role miRNA–microbiota...
To investigate antidepressant active ingredients of XYP (Xiaoyao Pill), while predicting its primary pharmacodynamic material basis and underlying mechanisms action. UPLC-Q-TOF-MS/MS was used to identify the XYP. In addition, based on analysis components, network pharmacology molecular docking were potential therapeutic targets possible signaling pathways in treatment depression. A total 102 chemical 10 prototype components 16 metabolites absorbed brain identified Network showed that these...
This study aimed to investigate the effects of daily weight gain and feed intake calves on first-lactation milk yield composition using a metaanalysis. A total 57 treatments from 18 studies were included in study. Univariate multivariate mixed models constructed for calf ADG, liquid DMI (LDMI), starter (SDMI), 305-d milk, fat, protein yields data insight into preweaning performance. revealed ADG was significantly positively correlated with during period. indicates that is significant...