A5069053193- Ruminant Nutrition and Digestive Physiology
- Reproductive Physiology in Livestock
- Endometrial and Cervical Cancer Treatments
- Systemic Lupus Erythematosus Research
- Bioenergy crop production and management
- Genetic and phenotypic traits in livestock
- Colorectal and Anal Carcinomas
- Animal health and immunology
- Inflammatory Biomarkers in Disease Prognosis
- Cervical Cancer and HPV Research
- Fatty Acid Research and Health
- Immune Cell Function and Interaction
- Effects of Environmental Stressors on Livestock
- RNA modifications and cancer
- Sepsis Diagnosis and Treatment
- Ovarian cancer diagnosis and treatment
- Biofuel production and bioconversion
- Research in Cotton Cultivation
- Forest Biomass Utilization and Management
- Reproductive System and Pregnancy
- Inflammation biomarkers and pathways
- Agriculture, Soil, Plant Science
- interferon and immune responses
- Monoclonal and Polyclonal Antibodies Research
- T-cell and B-cell Immunology
State Key Laboratory of Animal Nutrition
2020-2025
China Agricultural University
2021-2025
ETH Zurich
2022-2024
Inner Mongolia Medical University
2021-2024
University of Science and Technology of China
2024
First Affiliated Hospital of Zhengzhou University
2017-2023
Wuhan University
2018-2022
Zhongnan Hospital of Wuhan University
2018-2022
Anhui Provincial Hospital
2016-2021
Mongolian National University
2021
Paper mulberry (Broussonetia papyrifera; PM) is an excellent and extensive type of roughage in Asia. This study aimed to evaluate the effects PM silage on milk production, apparent digestibility, antioxidant capacity, fecal bacteria composition Holstein dairy cows. Forty-five lactating cows with a similar yield parity were selected randomly assigned three groups. The control group was fed non-PM diet, PM-treated groups 4.5 9.0% supplementary diets for 28 days. Then, treatment containing 13.5...
The drop of dry matter intake (DMI) and rise milk production in transitional dairy cows would mobilize reserved fat disrupt lipid metabolism, eventually attributed to negative energy balance (NEB) immune injury. positive effect n-3 polyunsaturated fatty acids (PUFA) on regulating metabolism inflammation has been elucidated, however, the lack regulatory mechanism deserves further investigation. In this study, 30 Holstein transition were divided into control (CON) HN3 groups based n-3: n-6...
High-yield dairy cows with high-concentrate diets are more prone to experiencing health problems associated rumen microbial imbalance. This study assessed the effects of Saccharomyces cerevisiae culture (SC), a food supplement, on ruminal pH, volatile fatty acid (VFA), inflammatory cytokines, and performance high-yield cows. Forty Holstein similar characteristics (e.g., milk yield, days milk, parity) were randomly divided into two groups: an experimental group fed basal ration supplemented...
The objective of this study was to determine the effect dietary supplementation n-3 polyunsaturated fatty acids (PUFA) and n-6 PUFA on dry matter intake (DMI), energy balance, oxidative stress, performance transition cows. Forty-five multiparous Holstein dairy cows with similar parity, body weight (BW), condition score (BCS), milk yield were used in a completely randomized design during 56-d experimental period including 28 d prepartum postpartum. At 240 pregnancy, randomly assigned one 3...
Introduction Early and effective application of antimicrobial medication has been evidenced to improve outcomes patients with bloodstream infection (BSI). However, conventional microbiological tests (CMTs) have a number limitations that hamper rapid diagnosis. Methods We retrospectively collected 162 cases suspected BSI from intensive care unit blood metagenomics next-generation sequencing (mNGS) results, comparatively evaluate the diagnostic performance clinical impact on antibiotics usage...
To better understand the transition of rumen function during weaning period in dairy calves, sixteen Holstein calves were selected and divided into two groups: pre-weaning (age = 56 ± 7 day, n 8) post-weaning 80 6 8). The fluid was obtained by an oral gastric tube. fermentation profile, enzyme activity, bacteria composition, their inter-relationship investigated. results indicated that had a higher acetate, propionate, butyrate, microbial crude protein (MCP) than (p < 0.05). pH lower...
This study evaluated the effects of different dietary n-6/n-3 polyunsaturated fatty acid (PUFA) ratios on in vitro ruminant fermentation. Methane production, composition, and microbial profiles were compared after fermentation rumen fluid collected from cows that had been fed isoenergetic isoproteic experimental diets at three ratios: 3.04 (HN6, high n-6 source), 2.03 (MN6, medium 0.8 (LN6, low source). The fermented pH total volatile (VFA) levels significantly decreased (p < 0.05) HN6...
Three main crop straws including corn straw (Zea mays, CS), rice (Oryza sativa, RS), and wheat (Triticum aestivum, WS), two forages alfalfa hay (Medicago AH) silage CSil) were analyzed in order to compare their ruminal degradability, indigestible neutral detergent fiber (iNDF), intestinal digestibility (ID), total-tract (TTD) of crude protein (CP), (NDF), acid (ADF) using both an situ nylon bag technique a mobile technique. The forage samples incubated the rumen for 6, 12, 16, 24, 36, 48,...
Forages are vital in maintaining the dietary structures of ruminants, and reducing their costs is important for improving dairy production efficiency. Thus, this study investigated effects forage types on dry matter intake, production, rumen fermentation, microbial profile peak-lactating cows. Eight cows (600 ± 25 kg) with days milk (60 10 days) were assigned to four groups using a replicated 4 × Latin square design: OG (oat hay + alfalfa corn silage concentrate), CW (Leymus chinensis AS...
This study mainly studied the effect of inhibition nuclear factor-κB (NF-κB) signal by pyrrolidine dithiocarbamate (PDTC) on lipopolysaccharide (LPS)-induced inflammatory response, oxidative stress, and mitochondrial dysfunction in a murine acute lung injury model. The results showed that LPS exposure activated NF-κB its upstream proteins caused inflammation, mice. While PDTC adminstration alleviated LPS-induced generation lymphocytes, IL-1β, TNF-α. Malondialdehyde, common product, was...
The transition period is the stage of high incidence metabolic and infectious diseases in dairy cows. Improving cows' health crucial for industry. This study aimed to determine effects dietary supplementation medium-chain fatty acids (MCFAs) on immune function, status, performance Twenty multiparous Holstein cows randomly assigned two treatments at 35 d before calving. 1) CON (fed basal 2) MCFA treatment (basal diet was supplemented an additional 20 g MCFAs mixture every day) until 70 after...
This study aims to investigate the effect of hydroxy-selenomethionine supplementation on in vitro rumen fermentation characteristics and microorganisms Holstein cows.Five substrates, including control (without selenium supplementation, CON), sodium selenite (0.3 mg kg-1 DM, SS03), (0.3, 0.6 0.9 SM03, SM06 SM09, respectively) were incubated with fluid vitro. The results showed that dry matter disappearance gas production at 48 h was significantly higher than SS03 CON; propionate total...
Respiratory rate (RR) is an important indicator of the health and welfare status dairy cows. In recent years, progress has been made in monitoring RR cows using video data learning methods. However, existing approaches often involve multiple processing modules, such as region interest (ROI) detection tracking, which can introduce errors that propagate through successive steps. The objective this study was to develop end-to-end computer vision method predict continuously automatically....
Cervical cancer is known to impair women's sexual function. This study aimed at investigating the attitudes and behavior of radiation oncologists regarding functioning female cervical patients who receive therapy.A total 186 were included. A self-reported questionnaire was used investigate oncologists. The queried on their history consultation issues, attitudes, toward issues considerations life for radiotherapy.Among 120 completed questionnaires, 101 (84.2%) had been consulted whom only 29...
Mucin 3A (MUC3A) is highly expressed in non-small cell lung cancer (NSCLC), but its functions and effects on clinical outcomes are not well understood. Tissue microarray of 92 NSCLC samples indicated that high levels MUC3A were associated with poor prognosis, advanced staging, low differentiation. knockdown significantly suppressed proliferation induced G1/S accumulation via downregulating cycle checkpoints. also inhibited tumor growth vivo had synergistic radiation. increased...
The present study investigates the effect of 50 mL AMCB taken daily as a dietary supplement on rumen fermentation, microbiota, and production performance 40 Holstein dairy cows in transition period with 2.76 ± 0.48 parity 650 25 kg body weight. supplementation stabilized pH, improved microbiota richness partial probiotic colonization, considerably increased dry matter intake, milk production, protein content, yield. Moreover, after calving, reduced serum blood urea nitrogen, malondialdehyde,...
Abstract Emulsifiers are essential for achieving a homogenous distribution of lipophilic supplements in vitro rumen fluid incubations. Since emulsifiers can alter fermentation, it is crucial to select one that minimally impacts fermentation parameters reduce potential biases. This study aimed evaluate seven emulsifiers’ impact on ruminal using the Hohenheim Gas Test order identify most inert emulsifier. Rumen fluids were collected from three non‐lactating Original Brown‐Swiss cannulated cows...
Transition dairy cows experience sudden changes in both metabolic and immune functions, which lead to many diseases postpartum cows. Therefore, it is crucial monitor guarantee the nutritional healthy status of transition The objective this study was determine effect diet enriched n-3 or n-6 polyunsaturated fatty acid (PUFA) on colostrum composition blood index multiparous Holstein neonatal calves during period. Forty-five at 240 days pregnancy were randomly assigned receive 1 3 isoenergetic...
To explore the characteristics of changes in peripheral blood lymphocyte subsets patients with sepsis intensive care unit (ICU) and analyze their predictive value for prognosis.The clinical data admitted to surgical (SICU) First Affiliated Hospital Zhengzhou University from January 2020 December 2021 were analyzed retrospectively. The met diagnostic criteria Sepsis-3 ≥ 18 years old. Peripheral venous samples collected all on next morning after admission SICU routine test subsets. According...