A5009351138- Alzheimer's disease research and treatments
- Cholinesterase and Neurodegenerative Diseases
- Health Sciences Research and Education
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 and healthcare impacts
- SARS-CoV-2 and COVID-19 Research
- Inflammasome and immune disorders
- Neurological diseases and metabolism
- Natural Antidiabetic Agents Studies
- Health and Medical Research Impacts
- RNA and protein synthesis mechanisms
- Natural product bioactivities and synthesis
- Computational Drug Discovery Methods
- RNA modifications and cancer
- Piperaceae Chemical and Biological Studies
- COVID-19 Clinical Research Studies
- Diet and metabolism studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Tryptophan and brain disorders
- Cancer-related cognitive impairment studies
- Organ and Tissue Transplantation Research
- Dementia and Cognitive Impairment Research
- Stress Responses and Cortisol
- Porphyrin Metabolism and Disorders
- Innovations in Medical Education
Deleted Institution
2024
University Health Network
2018-2023
Krembil Research Institute
2018-2023
Toronto Western Hospital
2023
Toronto General Hospital
2020-2023
University of Toronto
2020
The novel coronavirus SARS-CoV-2 has become a global health concern. morbidity and mortality of the potentially lethal infection caused by this virus arise from initial viral subsequent host inflammatory response. latter may lead to excessive release pro-inflammatory cytokines, IL-6 IL-8, as well TNF-α ultimately culminating in hypercytokinemia ("cytokine storm"). To address immuno-inflammatory pathogenesis, multiple clinical trials have been proposed evaluate anti-inflammatory biologic...
Pantothenate, the fundamental precursor to coenzyme A, is required for optimal growth and virulence of microbial pathogens. It synthesized by enzyme-catalyzed condensation β-alanine pantoate, which has shown susceptibility inhibition analogs its molecular constituents. Accordingly, are gaining inquiry as potential antimicrobial chemotherapeutics.We evaluated 35 derivatives β-alanine, substituted at α, β, amine, carboxyl sites, derived from in silico, dynamic modeling be competitive...
Healthcare is constantly evolving and thus requires lifelong learning. Evidence-based learning has been shown to lead better patient outcomes, yet many healthcare professionals report gaps in their research abilities. We sought evaluate the efficacy of a professional development program addressing identified gaps.