A5102027370- Acute Ischemic Stroke Management
- Liver Diseases and Immunity
- Stroke Rehabilitation and Recovery
- Cerebrovascular and Carotid Artery Diseases
- Liver Disease Diagnosis and Treatment
- Diabetes Management and Research
- Family and Disability Support Research
- Medication Adherence and Compliance
- Diabetes Treatment and Management
- Gallbladder and Bile Duct Disorders
- Autism Spectrum Disorder Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Infant Development and Preterm Care
- Dementia and Cognitive Impairment Research
- Pancreatitis Pathology and Treatment
- Parkinson's Disease Mechanisms and Treatments
- Chronic Disease Management Strategies
- Neurological Disorders and Treatments
- Diabetes Management and Education
- Health Systems, Economic Evaluations, Quality of Life
- Alkaline Phosphatase Research Studies
- Venous Thromboembolism Diagnosis and Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Mobile Health and mHealth Applications
- Cardiovascular Health and Disease Prevention
Intercept Pharmaceuticals (United States)
2024-2025
University of Alberta
2022-2024
Deleted Institution
2023-2024
La Trobe University
2021-2024
University of Manitoba
2024
The University of Queensland
2022-2023
Autism CRC
2022-2023
Kasturba Medical College Hospital
2022
Humana (United States)
2019-2022
Manipal Academy of Higher Education
2020-2022
There is limited published literature on longitudinal utilization of glucose-lowering agents (GLAs) among patients with type 2 diabetes (T2D) and cardiovascular disease (CVD or risk CVD). This retrospective, observational study aimed to provide updated evidence patient characteristics GLAs T2D CVD in the United States.This was a cross-sectional evaluation aged 50-89 years annual continuous enrolment Medicare Advantage Prescription Drug plan, identified from administrative claims data (Humana...
There are reports of decline in the rates acute emergency presentations during coronavirus disease 2019 (COVID-19) pandemic including stroke. We performed a meta-analysis impact COVID-19 on stroke and reperfusion therapy.Following Meta-analysis Of Observational Studies Epidemiology (MOOSE) guidelines, we systematically searched literature for studies reporting changes treatment before pandemic. Aggregated data were pooled using with random-effect models.We identified 37 observational...
Aim: To evaluate the clinical characteristics and healthcare resource utilization for acute care its costs patients with primary biliary cholangitis (PBC) or without cirrhosis. Materials & methods: This retrospective observational cohort study was conducted using two datasets (Komodo's Healthcare Map™ [Komodo Health] Optum Clinformatics® Data Mart [CDM] database) between 2015 2023. Patients (≥18 years) PBC were identified based on ≥1 inpatient ≥2 outpatient claims. (hospitalizations...
Elevated liver biochemistries are associated with increased risk of negative outcomes in patients primary biliary cholangitis (PBC). To evaluate whether longitudinal monitoring and fibrosis scores provides additional prognostic value to assess the relationship between degree elevation multiple biomarkers within different alkaline phosphatase (ALP) strata. Adults PBC were identified from Komodo's Healthcare Map. A Cox proportional hazards model examined time first occurrence hospitalisation...
Background: Prevalence estimates of primary biliary cholangitis (PBC) in the United States have evolved with introduction newer real-world data capture approaches. Little is known about geographic distribution PBC and health care provider (HCP) landscape for patients PBC. This study aimed to estimate prevalence States, assess regional variability its prevalence, describe HCPs Methods: Patients were identified using Komodo's Healthcare Map, a large national administrative claims database. per...
The objective of this study was to examine patient characteristics and health care resource utilization (HCRU) in the 36 months prior a confirmatory diagnosis Alzheimer's disease (AD) compared matched cohort without dementia during same time interval. Patients newly diagnosed with AD (with ≥2 claims) were identified between January 1, 2013 September 31, 2015, date second claim for defined as index date. enrolled at least no or codes (1:3) on age, gender, race/ethnicity, enrollment duration...
Characterizing patients with Parkinson's disease (PD) and cognitive impairment is important toward understanding their natural history.Understand clinical, treatment, cost characteristics of PD pre- post-cognitive (memory loss/mild impairment/dementia or dementia treatment) recognition.2,711 newly diagnosed (index) were identified using administrative claims data. They matched (1:1) on age gender to no (controls). These two cohorts compared patient characteristics, healthcare resource...
Background and Purpose— We investigated predictors for acute persisting periprocedural ischemic brain lesions among patients with symptomatic carotid stenosis randomized to stenting or endarterectomy in the International Carotid Stenting Study. Methods— assessed on diffusion-weighted imaging 1 3 days after treatment 124 107 fluid-attenuated inversion recovery month 86 75 patients, respectively. Results— had more (relative risk, 8.8; 95% confidence interval, 4.4–17.5; P <0.001) 4.2;...
Predictive risk models identifying patients at high for specific outcomes may provide valuable insights to providers and payers regarding points of intervention modifiable factors. The goal our study was build predictive identify with chronic kidney disease (CKD) type 2 diabetes (T2D) progression end stage (ESKD), mortality, hospitalization cardiovascular (CVD), cerebrovascular (CeVD), heart failure (HF).This a retrospective observational cohort utilizing administrative claims data in CKD...
Disease-modifying antirheumatic drugs (DMARDs) are recommended as the standard of care for patients with rheumatoid arthritis (RA) due to their ability reduce pain and disability; however, DMARD use is low in some subgroups RA population.
Background: The early detection of developmental conditions such as autism is vital to ensure children can access appropriate and timely evidence-based supports, services, interventions. Children who have undetected in life are more likely develop later health, developmental, learning, behavioral issues, which turn a cumulative effect over the course. Methods: current protocol describes multi-site, cluster randomized control trial comparing surveillance pathway for usual care, using...
Background In ischaemic stroke, minor deficits (National Institutes of Health Stroke Scale (NIHSS) ≤5) at presentation are common but often progress, leaving patients with significant disability. We compared the efficacy and safety intravenous thrombolysis tenecteplase versus alteplase in who had a stroke enrolled Alteplase Compared to Tenecteplase Patients With Acute Ischemic (AcT) trial. Methods The AcT trial included individuals aged >18 years, were eligible for standard-of-care...
Abstract There are inequities in engagement with established early childhood developmental surveillance programs, eclipsing disadvantaged families. The current study sought to address this by dovetailing immunization visits and other opportunistic contacts children at general practices). While 53 General Practices were recruited, significant COVID-19 disruptions resulted only 81 being screened (both parent-administered GP completed). Of the children, 11 positive all of them along 5% screen...
BACKGROUND: Prostaglandin analogs (PGAs) are considered an initial therapy to manage increased intraocular pressure (IOP) for patients with glaucoma. When the PGA treatment fails lower IOP adequately, patient may add or change medications have surgery/laser treatment. OBJECTIVE: To compare medication adherence, duration of therapy, and patterns among 3 PGAs—latanoprost, travoprost, bimatoprost—as therapies glaucoma ocular hypertension. METHODS: This was a retrospective cohort study using...
ABSTRACT: Background: Early reperfusion has the best likelihood for a favorable outcome in acute ischemic stroke (AIS) with large vessel occlusion (LVO). Our experience mobile unit (MSU) direct to angiosuite (DTAS) transfer AIS patients suspected LVO is presented. Methods: Retrospective review of prospectively collected data from November 2019 August 2022, evaluated and transferred by University Alberta Hospital MSU moved endovascular thrombectomy (EVT). Result: A total 41 cases were...
Objectives Implementing support and services early in the life course has been shown to promote positive developmental outcomes for children at high likelihood of conditions including autism. This study examined parents’/caregivers’ experiences perceptions about a digital surveillance pathway autism, autism (ASP), usual care, as (SaU) pathway, primary healthcare general practice setting. Design qualitative involves using convenience selection process full sample parents/caregivers that...
Abstract Background: Significant challenges remain in the early identification of child developmental conditions community. Implementing supports and services life course has been shown to promote positive outcomes for children at high likelihood including autism. As part a cluster randomised controlled trial, this study seeks examine compare perspectives experiences Australian general practitioners (GPs) relation digital surveillance program autism usual care pathway, practice clinics....
Abstract Background Significant challenges remain in the early identification of child developmental disabilities community. Implementing supports and services life course has been shown to promote positive outcomes for children at high likelihood disabilities, including autism. As part a cluster randomised controlled trial, this study seeks examine compare perspectives experiences Australian general practitioners (GPs) relation digital surveillance program autism usual care pathway,...
To describe and compare real-world treatment patterns clinical outcomes among individuals with immune thrombocytopenia (ITP) receiving second-line therapies (rituximab, romiplostim, or eltrombopag).