A5030488381- Cerebrovascular and Carotid Artery Diseases
- Advanced MRI Techniques and Applications
- Intracranial Aneurysms: Treatment and Complications
- Acute Ischemic Stroke Management
- Vascular Malformations Diagnosis and Treatment
- Advanced Neuroimaging Techniques and Applications
- MRI in cancer diagnosis
- Cardiovascular Health and Disease Prevention
- Spinal Fractures and Fixation Techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- Spine and Intervertebral Disc Pathology
- Cerebral Venous Sinus Thrombosis
- Cerebrospinal fluid and hydrocephalus
- Pelvic and Acetabular Injuries
- Neurosurgical Procedures and Complications
- Stroke Rehabilitation and Recovery
- Infectious Diseases and Tuberculosis
- Venous Thromboembolism Diagnosis and Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Aortic Disease and Treatment Approaches
- Glioma Diagnosis and Treatment
- Ophthalmology and Eye Disorders
- Neuroscience and Music Perception
- Long-Term Effects of COVID-19
- Management of metastatic bone disease
Klinik Hirslanden
2010-2025
Molecular Templates (United States)
2018-2023
Hospital de Egas Moniz
2022
University of Thessaly
2022
Boston University
2022
Boston Medical Center
2022
University Medical Center Utrecht
2012-2015
University Hospital of Basel
2001-2012
Academic Medical Center
2012
Northern General Hospital
2012
<h3>BACKGROUND AND PURPOSE:</h3> Endoluminal reconstruction with flow diverting devices represents a novel constructive technique for the treatment of cerebral aneurysms. We present results first prospective multicenter trial flow-diverting construct intracranial <h3>MATERIALS METHODS:</h3> Patients unruptured aneurysms that were wide-necked (>4 mm), had unfavorable dome/neck ratios (<1.5), or failed previous therapy enrolled in PITA between January and May 2007 at 4 (3 European 1...
BackgroundThe International Carotid Stenting Study (ICSS) of stenting and endarterectomy for symptomatic carotid stenosis found a higher incidence stroke within 30 days compared with endarterectomy.We aimed to compare the rate ischaemic brain injury detectable on MRI between two groups.Methods Patients recently artery enrolled in ICSS were randomly assigned 1:1 ratio receive or endarterectomy.Of 50 centres ICSS, seven took part substudy.The protocol specifi ed that was done 1-7 before...
To assess inter- and intraobserver reproducibility for different techniques of measuring relative cerebral blood volume (rCBV) in patients with intracranial mass lesions.Three independent observers (neuroradiology fellows) who were blinded to the histopathologic diagnosis performed rCBV measurements 50 various lesions. Three methods compared. With method 1, placement a single region interest was guided by color overlay map. 2 3, highest value mean repeated measurements, respectively,...
Background and Purpose— The introduction of flow diverters (FDs) has expanded the possibilities for reconstructive treatment difficult intracranial aneurysms. Concern remains as to long-term patency perforating arteries side branches covered during stent placement. Our purpose was evaluate performance early effect on after implantation Silk FD in basilar artery Methods— Twelve patients with an aneurysm that treated by were included our retrospective study. Both unruptured previously...
Intravenous thrombolysis for acute ischemic stroke is usually based on clinical assessment, blood test results, and CT findings. of mimics may occur but has not been studied in detail.We determined frequency, characteristics, outcome mimic patients versus with treated intravenous using data a prospective, single-center bank.Among 250 patients, 243 (97.2%) had strokes 7 (2.8%) were mimics. Seizure was the most frequent diagnosis among There trend toward lower National Institutes Health Stroke...
Training can change the functional and structural organization of brain, animal models demonstrate that hippocampus formation is particularly susceptible to training-related neuroplasticity. In humans, however, direct evidence for plasticity adult induced by training still missing. Here, we used musicians' brains as a model test plastic capabilities human hippocampus. By using magnetic resonance imaging optimized investigation auditory processing, examined brain responses temporal novelty in...
Article abstract Unilateral acoustic stimulation produces a functional MRI (fMRI)–blood-oxygenation-level-dependent (BOLD) response mainly in the contralateral auditory cortex. In unilateral deaf patients, BOLD is bilateral. We studied subject with sudden hearing loss after cochlear nerve resection before and repeatedly surgery. During normal bilateral hearing, cortical responses were found. Progressing compensatory reorganization representation of was detected over period approximately 1 year.
Dynamic, contrast-enhanced MRI (deMRI) is increasingly being used to evaluate cerebral microcirculation. There are two different approaches for analyzing deMRI data. Intravascular indicator dilution theory has been estimate blood volume (and perfusion), usually from T(2)- or T(2) (*)-weighted images of the first pass bolus. However, assumes that tracer (i.e., contrast agent) remains intravascular, which often not case when blood-brain barrier (BBB) damaged. Furthermore, method provides no...
Ruptured aneurysms of < 2 mm are not amenable to endovascular coiling and therefore pose a significant treatment challenge.To test recently introduced flow diverters that allow reconstruction via another method may represent new option for such lesions.Three female patients presented with acute subarachnoid hemorrhage. An aneurysm was identified in all as the cause bleeding. The were located at C2 segment internal carotid on basilar bifurcation other. All had failed early attempts. Flow...
<h3>BACKGROUND AND PURPOSE:</h3> MR including MRV is an established method to diagnose CVT. However, it remains unsettled which imaging modalities offer the highest diagnostic accuracy. We evaluated accuracy of a combined, dynamic (1.5 seconds per dataset) and static (voxel size, 1.1 × 0.9 1.5 mm), contrast-enhanced (combo-4D MRV) relative other MR/MRV modalities. <h3>MATERIALS METHODS:</h3> A total 39 patients with CVT (<i>n</i> = 20) control subjects 19) underwent combo-4D MRV, 2D TOF GRE...
Abstract Purpose To analyze and compare three quantitative MRI methods to determine the degree of muscle involvement in oculopharyngeal muscular dystrophy (OPMD). Materials Methods Muscle fat content (MFC) was determined based on water–fat quantification using a 2‐point Dixon (2PD) method histogram analysis free induction decay (FID) signal gradient‐spoiled steady‐state precession (SSFP) sequence. In addition, transverse relaxation times (T 2 ) tissue were calculated monoexponential model....
In a substudy of the International Carotid Stenting Study (ICSS), more patients had new ischemic brain lesions on diffusion-weighted magnetic resonance imaging (MRI) after stenting (CAS) than endarterectomy (CEA). present analysis, we compared characteristics MRI lesions.Number, individual and total volumes, location were in with symptomatic carotid stenosis randomized to CAS (n=124) or CEA (n=107) ICSS-MRI substudy.CAS higher lesion numbers (1 lesion, 15% vs 8%; 2-5 lesions, 19% 5%; >5 16%...
<h3>Background and Objectives</h3> COVID-19–related inflammation, endothelial dysfunction, coagulopathy may increase the bleeding risk lower efficacy of revascularization treatments in patients with acute ischemic stroke (AIS). We aimed to evaluate safety outcomes AIS COVID-19. <h3>Methods</h3> This was a retrospective multicenter cohort study consecutive receiving intravenous thrombolysis (IVT) and/or endovascular treatment (EVT) between March 2020 June 2021 tested for severe respiratory...
Background In pediatric patients, obstruction of the upper airway is a common problem during general anesthesia. Chin lift commonly used technique to improve patency. However, little known about mechanism underlying this technique. Methods The authors studied effect chin maneuver on dimensions in 10 spontaneously breathing children (aged 2-11 yr) sedated with propofol routine magnetic resonance imaging. minimal anteroposterior and corresponding transverse diameters pharynx were determined at...
<b><i>Objective:</i></b> To study the association between diffusion-weighted imaging (DWI) characteristics and stroke etiology, severity, functional outcome in patients with infratentorial strokes. <b><i>Methods:</i></b> The authors prospectively studied 22 consecutive acute They used a blinded comparison of DWI features (number, distribution, volume lesions) clinical characteristics, namely, etiology (Trial ORG 10172 Acute Stroke Treatment [TOAST] classification), severity (NIH Scale...