Jeffrey Stolp
A5026682111- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Atherosclerosis and Cardiovascular Diseases
- Venous Thromboembolism Diagnosis and Management
- Long-Term Effects of COVID-19
- COVID-19 and healthcare impacts
- Inflammatory Biomarkers in Disease Prognosis
- Adipokines, Inflammation, and Metabolic Diseases
- Blood Coagulation and Thrombosis Mechanisms
- Cancer, Lipids, and Metabolism
- Intracerebral and Subarachnoid Hemorrhage Research
- Stroke Rehabilitation and Recovery
- Trauma and Emergency Care Studies
- Traumatic Brain Injury and Neurovascular Disturbances
University of Amsterdam
2021-2024
Amsterdam University Medical Centers
2021-2024
Hospital de Egas Moniz
2022
University of Thessaly
2022
Boston University
2022
Boston Medical Center
2022
Amsterdam Neuroscience
2022
<h3>Background and Objectives</h3> COVID-19–related inflammation, endothelial dysfunction, coagulopathy may increase the bleeding risk lower efficacy of revascularization treatments in patients with acute ischemic stroke (AIS). We aimed to evaluate safety outcomes AIS COVID-19. <h3>Methods</h3> This was a retrospective multicenter cohort study consecutive receiving intravenous thrombolysis (IVT) and/or endovascular treatment (EVT) between March 2020 June 2021 tested for severe respiratory...
The association of COVID-19 with higher bleeding risk and worse outcomes in acute ischemic stroke (AIS) undergoing revascularization may be related to the presence infection symptoms. We aimed assess safety treatments patients AIS asymptomatic (AS-COVID) or symptomatic (S-COVID).
Abstract Objective To investigate the prognostic value of white blood cell count (WBC) on functional outcome, mortality and bleeding risk in stroke patients treated with intravenous thrombolysis (IVT). Methods In this prospective multicenter study from TRISP registry, we assessed association between WBC admission 3-month poor outcome (modified Rankin Scale 3–6), occurrence symptomatic intracranial hemorrhage (sICH; ECASS-II-criteria) IVT-treated patients. was used as continuous categorical...
The probability to receive intravenous thrombolysis (IVT) for treatment of acute ischemic stroke declines with increasing age and is consequently the lowest in very elderly patients. Safety concerns likely influence individual IVT decisions. Using data from a large registry, we aimed provide more evidence on safety elderly.In this prospective multicenter study TRISP (Thrombolysis Ischemic Stroke Patients) compared patients ≥90 years those <90 using symptomatic intracranial hemorrhage (ECASS...
Background: Patients with large vessel occlusion (LVO) stroke are often initially admitted to a primary center (PSC) and subsequently transferred comprehensive (CSC) for endovascular thrombectomy (EVT). This interhospital transfer delays initiation of EVT. To identify potential workflow improvements, we analyzed pre- time metrics patients LVO who were from PSC Methods: We used data the regional emergency medical services our EVT registry. included three nearby PSCs (2014–2021). The interval...
The early management of transferred patients with a large vessel occlusion (LVO) stroke could be improved by identifying who are likely to recanalize early. We aim predict recanalization based on patient clinical and thrombus imaging characteristics. included 81 anterior-circulation LVO an recanalization, defined as the resolution or migration distal location not reachable endovascular treatment upon repeated radiological imaging. compared their characteristics all (322) persistent in MR...
Abstract Background: Inflammation is important in the development of atherosclerosis. Research suggested sex-dependent differences for value inflammatory markers risk stratification stroke patients with internal carotid artery stenosis (ICAS). We investigated whether leukocytes and thrombocytes were associated ≥50% ICAS acute this was sex-dependent. Methods: Patients included PASS evaluated predictive ICAS. In ischemic or TIA randomized between four days ceftriaxone intravenously standard...
Abstract Background Increasing evidence suggests that inflammation inside the vessel wall has a prominent role in atherosclerosis. In particular carotid atherosclerosis, vulnerable plaque characteristics are strongly linked to an increased stroke risk. An association between leukocytes and not been investigated before could help with gaining knowledge of vulnerability, which contribute new target for intervention. this study, we leukocyte count characteristics. Methods All patients from...