A5084879329- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Vascular Malformations Diagnosis and Treatment
- Neuroscience and Neuropharmacology Research
- EEG and Brain-Computer Interfaces
- Cerebral Venous Sinus Thrombosis
- Neurological and metabolic disorders
- Psychosomatic Disorders and Their Treatments
- Intracranial Aneurysms: Treatment and Complications
- scientometrics and bibliometrics research
- International Relations in Latin America
- Bipolar Disorder and Treatment
- Neurological disorders and treatments
- Schizophrenia research and treatment
- Diet and metabolism studies
- Tuberous Sclerosis Complex Research
- Cannabis and Cannabinoid Research
- Scientific Research and Technology
- Economic Zones and Regional Development
- Functional Brain Connectivity Studies
- Inflammatory Myopathies and Dermatomyositis
- Amino Acid Enzymes and Metabolism
- Genomics and Rare Diseases
- Cardiac electrophysiology and arrhythmias
- IgG4-Related and Inflammatory Diseases
Centre Hospitalier Universitaire de Sherbrooke
2022-2025
Université de Sherbrooke
2022-2025
Centre Hospitalier de l’Université de Montréal
2020-2025
Université de Montréal
2020-2025
Deleted Institution
2022-2024
National University of Malaysia
2023
Southwest Bahia State University
2023
McGill University Health Centre
2023
Shanghai University
2023
City University of Hong Kong
2023
Importance How epilepsy may promote cardiovascular disease remains poorly understood. Objective To estimate the odds of new-onset events (CVEs) over 6 years in older people with vs without epilepsy, exploring how enzyme-inducing antiseizure medications (EIASMs) and traditional risk factors mediate these odds. Design, Setting, Participants This was a prospective cohort study using comprehensive Canadian Longitudinal Study on Aging (CLSA), follow-up (2015-2021, analysis performed December...
Abstract Objective Tuberous sclerosis complex (TSC) is a monogenetic disorder associated with sustained mechanistic target of rapamycin (mTOR) activation, leading to heterogeneous clinical manifestations. Epilepsy and renal angiomyolipoma are the most important causes morbidity in adult people TSC (pwTSC). mTOR key player inflammation, which turn could influence TSC‐related Reliable biomarkers lacking monitor predict evolution response treatment for epilepsy pwTSC. Inflammation has been...
People with epilepsy are at risk of cardiac arrhythmias. Whether this association results from epilepsy, antiseizure medications (ASMs) such as sodium channel blockers (NABs), or other factors has not been systematically assessed. The aims study were to quantify the odds conduction delays (CCDs) on electrocardiogram in older people active using vs NABs, determine prevalence CCDs by and examine demographic clinical CCDs. This was a cross-sectional Canadian Longitudinal Study Aging. We defined...
Tuberous sclerosis complex (TSC) is a genetic disease characterised by the growth of benign tumours. The Associated Neuropsychiatric Disorders (TAND) Checklist used to identify patient-reported neurocognitive deficits. Patients may, however, under-recognise mild cognitive impairment. We aimed determine frequency abnormal scores on three objective tests function in people with and without diagnosed intellectual disability examine associations between these self-reported TAND symptoms....
Background: Epilepsy surgery failure is not uncommon, with several explanations having been proposed. In this series, we detail cases of epilepsy subsequently attributed to insular involvement. Methods: We retrospectively identified patients investigated at the monitoring units two Canadian tertiary care centers (2004–2020). Included were adults who had undergone surgeries recurrence seizures post-operatively and determined have an epileptogenic focus. Clinical, electrophysiological,...
ABSTRACT: Background: Guidelines on epilepsy monitoring unit (EMU) standards have been recently published. We aimed to survey Canadian EMUs describe the landscape of safety practices and compare these recommendations from new guidelines. Methods: A 34-item was created by compiling questions EMU structure, patient monitoring, equipment, personnel, standardized protocol use, use injury prevention tools. The questionnaire distributed online 24 hospital centers performing video-EEG (VEM) in...
Objective To study the outcome of patients with psychogenic non-epileptic seizures (PNES) after their diagnosis in epilepsy monitoring unit (EMU). Methods Patients diagnosed our EMU definite PNES between January 2009 and May 2023 were contacted by phone, those who agreed to participate asked a set predetermined questions. Comparative analyses carried out on several variables before diagnosis: number participants daily PNES, visits emergency department, consulted general practitioner or...
There is limited data on the utility, yield, and cost efficiency of genetic testing in adults with epilepsy. We aimed to describe yield utility panels our adult epilepsy clinic.We performed a retrospective, cross-sectional study all patients followed by an epileptologist at Canadian tertiary care centre's clinic between January 2016 August 2021 for whom panel was ordered. A generally ordered when etiology unknown or presence malformation cortical development. determined positivity confirmed...
ABSTRACT: Background: Intervention time (IT) in response to seizures and adverse events (AEs) have emerged as key elements epilepsy monitoring unit (EMU) management. We performed an audit of our EMU, focusing on IT AEs. Methods: a retrospective study all clinical admissions over 1-year period at Canadian academic tertiary care center’s EMU. This EMU was divided two subunits: daytime three-bed department subunit (EDU) supervised by EEG technicians neurology ward (NWU) equipped with video-EEG...
Caring for women with epilepsy (WWE) during pregnancy poses unique challenges. We conducted an audit of the care our clinic provided to pregnant WWE.We performed a retrospective study on all pregnancies followed by epileptologist at Canadian tertiary centre's between January 2003 and March 2021. Among 81 in 53 patients, 72 50 patients were analyzed determine patient-related, follow-up-related, antiseizure-medication-related, child-related characteristics. Univariate analyses explore if these...
To evaluate the reliability and accuracy of nonaneurysmal perimesencephalic subarachnoid hemorrhage (NAPSAH) on Noncontrast Head CT (NCCT) between numerous raters. 45 NCCT adult patients with SAH who also had a catheter angiography (CA) were independently evaluated by 48 diverse raters; raters performed second assessment one month later. For each case, asked: 1) whether they judged bleeding pattern to be perimesencephalic; 2) there was blood anterior brainstem; 3) complete filling...
We aimed to estimate (1) the odds of new-onset vascular events (VEs) over six years in people with epilepsy (PWE) versus without and (2) mediation effects use enzyme-inducing antiseizure medications (EIASMs) risk factors on association between VEs. There is evidence that there exists a bidirectional relationship disease. A higher incidence VEs PWE could be explained by EIASM worse health due socioeconomic factors. This study focused cohort 27,230 Canadians aged 45-85 at baseline from...
Optimizing patient safety in the epilepsy monitoring unit (EMU) has become a topic of increasing interest. We performed an audit our center's new single-floor EMU, assessing intervention rate (IR), time (IT), and adverse events (AEs).
There are rich legacies of geographical knowledge in China. However, geography as an independent branch science was established the country no earlier than beginning twentieth century. Since 1950s, integrated physical a subdiscipline China has made major theoretical and methodological progress areas regionalization, land studies, studies man-nature interactions. Despite this, discipline whole still faces tremendous challenges from fast changing society scientific advancement twenty-first The...