- Heart Failure Treatment and Management
- Frailty in Older Adults
- Nutrition and Health in Aging
- Nutritional Studies and Diet
- Bone health and osteoporosis research
- Curcumin's Biomedical Applications
- Chronic Disease Management Strategies
- Parathyroid Disorders and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Advanced Chemical Sensor Technologies
- Vitamin D Research Studies
- Bone health and treatments
- Genomics, phytochemicals, and oxidative stress
- Legionella and Acanthamoeba research
- Adipose Tissue and Metabolism
- Urinary Tract Infections Management
- Thyroid and Parathyroid Surgery
- Sodium Intake and Health
- Cardiovascular Function and Risk Factors
- Diet and metabolism studies
- COVID-19 Clinical Research Studies
- Hip and Femur Fractures
- Blood Pressure and Hypertension Studies
- Wound Healing and Treatments
- Metabolism, Diabetes, and Cancer
Campus Bio Medico University Hospital
2017-2024
Università Campus Bio-Medico
2014-2023
University of Milano-Bicocca
2022-2023
Azienda Ospedaliera San Gerardo
2022
John Wiley & Sons (United States)
2019
Abstract Context The clinical and radiological aspects of normocalcemic hyperparathyroidism (NHPT) are confounded by the differing methods used to rule out secondary small sample size. Objective To assess clinical, biochemical, profile NHPT compared with primary (PHPT) control subjects Design Multicentric cross-sectional study Setting Outpatient clinic Patients 47 NHPT, 41 PHPT, 39 age- sex-matched subjects. Main Outcome Measures Calcium metabolism bone turnover markers (BTMs). Lumbar spine,...
Irisin is a hormonelike molecule that cleaved and secreted by an unknown protease from fibronectin type III domain-containing protein 5 (FNDC5). It ameliorates bone status muscle atrophy influences energy homeostasis. PTH exerts several metabolic effects may interact with the of irisin.To test hypothesis irisin mutually affect their biological action, we evaluated FNDC5 mRNA expression in myotubes treated (1-34) parathyroid hormone receptor (PTH-r) osteoblasts r-irisin. To confirm vivo...
Objective: Evidence about the role of nutritional status (NS) on functional outcomes (FO) after rehabilitation in older adults is scarce. Our aim was to analyze association between NS and FO admitted geriatric units.Methods: The Sarcopenia And Function Aging Rehabilitation (SAFARI) multicenter study enrolled patients aged ≥65 years units Italy Spain. were absolute relative gain (AFG-RFG) Barthel Index (BI) at 1 3 months admission. (Mini Nutritional Assessment–Short Form) explored using...
Older adults are frequently stigmatized for improper emergency department (ED) visits and hospitalizations. In this study, we aimed to investigate the relationship between age appropriateness of ED visits, mismatching clinical severity hospitalizations.We carried out a nationwide assessment Italian Informative System Emergency Urgency data from 1 January 2015 31 December including patients admitted all EDs any reason. Appropriateness was defined as yellow/red/black color code (potentially...
Background: Analysis of exhaled volatile organic compounds (VOCs) may be applied for diagnostic purposes in some chronic diseases, but there are no data on their role discriminating people with congestive heart failure (CHF), particularly older patients where natriuretic peptides have lower accuracy. We evaluated whether VOCs analysis can discriminate or without CHF, stratify CHF severity and predict the response to therapy decompensated CHF. Methods Results: recruited 89 subjects admitted...
Kodamaea ohmeri is an emerging fungus recognised as important pathogen in immunocompromised hosts, responsible for life-threatening infections.
COVID-19 may have a heterogeneous onset, especially in older age. However, whether and how signs symptoms present aggregate together according to sociodemographic health factors is unclear, as well their prognostic value. This study included 981 inpatients who participated the GeroCovid Observational study. Signs/symptoms at disease sociodemographic, health, cognitive status, mobility were systematically recorded. Clusters of signs/symptoms identified through agglomerative hierarchical...
Dipstick test is widely used to support the diagnosis of urinary tract infections (UTI). It effective in ruling out UTI, but urine culture needed for confirmation. In this study we compared accuracy voltammetric analysis (VA) with that DT detect UTI (diagnosed using culture), and its usefulness as a second-stage people positive DT.142 patients were enrolled no exclusion criteria. VA was performed BIONOTE device. Partial Least Square Discrimination Analysis predict based on data; diagnostic...
The timely recognition of leg ulcers (LU) etiology and infection is pivotal to optimize management accelerate healing. objective this proof-of-concept study was test the diagnostic performance voltammetric analysis (VA) on ulcer exudate identify LU etiology, infection, predict clinical course. We enrolled 25 patients aged ≥60 years, affected by 42 venous/arterial LU. Clinical examination (Leg Ulcer Measurement Tool score, LUMT), swab culture, VA were performed at baseline 30 days. ability...
To investigate the relationship between hemoglobin and N-terminal pro B-type natriuretic peptide (NT-proBNP) concentration in hospitalized older adults with or without a diagnosis of heart failure (HF).Cross-sectional study based on retrospective hospital records review.Geriatric acute care ward.Individuals aged 65 (N = 226; mean age 81.1), (n 104) 122) HF.Information was collected demographic characteristics, comorbidities, laboratory echocardiographic data. The NT-proBNP evaluated using...