K. H. Chan

ORCID: 0000-0002-3681-8360
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Research Areas
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Myasthenia Gravis and Thymoma
  • Optical Imaging and Spectroscopy Techniques
  • S100 Proteins and Annexins
  • Neurosurgical Procedures and Complications
  • Antifungal resistance and susceptibility
  • Infectious Diseases and Tuberculosis
  • Thyroid and Parathyroid Surgery
  • Fungal Infections and Studies
  • Acute Ischemic Stroke Management
  • Traumatic Brain Injury Research
  • Cerebrospinal fluid and hydrocephalus
  • Parkinson's Disease and Spinal Disorders
  • Anesthesia and Neurotoxicity Research
  • Soft tissue tumor case studies
  • Neurogenetic and Muscular Disorders Research
  • Atrial Fibrillation Management and Outcomes
  • Information Systems Theories and Implementation
  • Innovative Approaches in Technology and Social Development
  • Cerebral Venous Sinus Thrombosis
  • Eosinophilic Disorders and Syndromes
  • Congenital Diaphragmatic Hernia Studies
  • Infections and bacterial resistance
  • Parkinson's Disease Mechanisms and Treatments
  • Inflammatory Myopathies and Dermatomyositis

University of Edinburgh
1992-2024

Queen Mary Hospital
1984-2015

University of Hong Kong
1983-2015

Queen Mary University of London
2005

Western General Hospital
1992-1993

Chinese University of Hong Kong
1990

Tri-Service General Hospital Songshan Branch
1990

Cerebral infarction (CI) is a serious complication of tuberculous meningitis (TBM). It can be asymptomatic or symptomatic, causing stroke. We studied 40 TBM patients. All had initial CT brain scan, CT/MRI scan 3 months later and urgent for deterioration. CI was classified into lacunar (LI) large artery (LAI). Twelve (30%) CI, in 9 (23%) it symptomatic (8%) silent. Seven (58%) LAI +/- LI. Eight (67%) multiple CI. Two died from brainstem 6 were dependent at 1 year. Patients with might develop...

10.1159/000085568 article EN Cerebrovascular Diseases 2005-01-01

Middle cerebral artery (MCA) blood flow velocity was measured daily by transcranial Doppler ultrasonography in 121 patients with severe (50), moderate (16) and minor (55) head injury during their hospital stay, the results compared findings control subjects. Admission MCA significantly lower after 35.8 (31.9-39.7) cm/s, mean (95% confidence limits), 45.5 (40.0-51.0) cm/s 51.7 (47.9-55.5) when normal controls 60.1 (56.9-63.3) cm/s. Initial than injury. At discharge, remained below 46.2...

10.1136/jnnp.55.9.787 article EN Journal of Neurology Neurosurgery & Psychiatry 1992-09-01

To successfully match the treatment to cause for raised intracranial pressure (ICP) after a severe head injury, it is important know underlying mechanism at given moment pressure. In particular, distinguish between active cerebral vasodilation, indicating functional autoregulation, and passive vascular dilation as ICP. An experimental study was performed in feline models of diffusely ICP (n = 6), arterial vasodilation caused by hypercarbia pharmacologically induced hypertension 6) determine...

10.1227/00006123-199305000-00014 article EN Neurosurgery 1993-05-01

Worldwide, the incidence of motor neuron disease (MND) has been increasing steadily over recent decades. We reported a follow-up epidemiology study MND in this locality.We identified subjects from computer database government hospital system between I January 1997 and 31 2002 by searching ICD code starting 335.xx. Every retrieved case or their records were reviewed validated neurologist(s) responsible regional hospitals which patients attended. One hundred twenty cases seven (serving 48.05%...

10.1080/14660820510028412a article EN Amyotrophic Lateral Sclerosis 2005-01-01

• Focal myositis is an inflammatory pseudotumor of skeletal muscle that may involve the head and neck. It can closely mimic either a neoplastic or infectious process. We present case 7-year-old boy with 2-week history painful, unilateral neck swelling, fever, torticollis. He failed to respond antibiotic therapy required open exploration. An incisional biopsy indurated, tissue adherent his sternocleidomastoid showed focal myositis. unusual, but important possibility in differential diagnosis...

10.1001/archotol.1991.01870130109027 article EN Archives of Otolaryngology - Head and Neck Surgery 1991-01-01

Eleven patients with raised intracranial pressure caused by cerebral cryptococcosis developed complications requiring neurosurgical operations. Two were fully conscious on admission, and 9 had impaired consciousness, four of whom comatose. Seven found to have hydrocephalus only. edema initially, 2 cystic lesions. One the latter subdural effusion. All eventually progressive placement a ventriculoperitoneal shunt. Four initially treated external ventricular drainage. When drainage was used...

10.1097/00006123-198907000-00008 article EN Neurosurgery 1989-07-01

A retrospective review of 526 patients who underwent neurosurgery for nontraumatic conditions over a 5-year period revealed 36 (6.8%) with endoscopically and or surgically documented postoperative gastrointestinal (GI) complications. Two had GI bleeding perforation, the remaining only. Multivariate analysis indicated 5 factors that were independent significance in predicting development These included 1) inappropriate secretion antidiuretic hormone, 2) preoperative coma (Glasgow Coma Score...

10.1097/00006123-198909000-00010 article EN Neurosurgery 1989-09-01

Journal Article Acute haemodynamic and myocardial metabolic effects of intravenous urapidil in severe heart failure Get access R. Y. C. WANG, WANG University Department Medicine, Queen Mary HospitalHong Kong Requests for reprints to: Dr Wang, Hospital, Pokfulam Road, Hong Kong. Search other works by this author on: Oxford Academic PubMed Google Scholar J. S. F. CHOW, CHOW K. H. CHAN, CHAN M. PAN, PAN P. WONG European Heart Journal, Volume 5, Issue 9, September 1984, Pages 745–751,...

10.1093/oxfordjournals.eurheartj.a061736 article EN European Heart Journal 1984-09-01

Ischaemic brain damage is present in over 90% of patients suffering from fatal head injury. Early detection and treatment ischemia may improve outcome after trauma. Monitoring blood flow velocity the middle cerebral artery by noninvasive transcranial doppler ultrasound provides an alternate means identifying ischaemia.

10.1007/978-3-7091-9302-0_14 article EN 1993-01-01

Mycobacterium fortuitum is a rare cause of central nervous system infection; however, shunt infection caused by this organism has not been reported. We report case subsequent to insertion ventriculoatrial for obstructive hydrocephalus cerebellar hematoma. The was controlled removal the and combination systemic intraventricular administration amikacin, oral ofloxacin. discussed pertinent literature reviewed. (Neurosurgery 29:472-474, 1991)

10.1097/00006123-199109000-00028 article EN Neurosurgery 1991-09-01

TO SUCCESSFULLY MATCH the treatment to cause for raised intracranial pressure (ICP) after a severe head injury, it is important know underlying mechanism at given moment pressure. In particular, distinguish between active cerebral vasodilation, indicating functional autoregulation, and passive vascular dilation as ICP. An experimental study was performed in feline models of diffusely ICP (n = 6), arterial vasodilation caused by hypercarbia pharmacologically induced hypertension 6) determine...

10.1097/00006123-199305000-00014 article EN Neurosurgery 1993-05-01

To evaluate RV longitudinal function in pulmonary hypertension (PH) patients by Two-dimensional strain (2DS). 41 with PH were prospectively studied along 40 control patients. 2DS and right heart catheterization performed, peak systolic strain(S) rate (SRs) obtained from basal to apical free wall calculated. Deformation indices compared values of conventional echocardiography the use linear regression. (1) S, SRs all segments group significantly lower than those (P <0.05); middle segment...

10.1093/eurheartj/sur028 article EN European Heart Journal Supplements 2012-02-01
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