A5100714565- Epilepsy research and treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastric Cancer Management and Outcomes
- Pancreatic and Hepatic Oncology Research
- Neuroscience and Neuropharmacology Research
- Non-Invasive Vital Sign Monitoring
- Pharmacological Effects and Toxicity Studies
- Gallbladder and Bile Duct Disorders
- Cancer Mechanisms and Therapy
- Advanced MRI Techniques and Applications
- Family and Patient Care in Intensive Care Units
- HER2/EGFR in Cancer Research
- Genetics and Neurodevelopmental Disorders
- Intensive Care Unit Cognitive Disorders
- Lung Cancer Research Studies
- Adipose Tissue and Metabolism
- Colorectal Cancer Treatments and Studies
- Amino Acid Enzymes and Metabolism
- Congenital heart defects research
- Neurogenesis and neuroplasticity mechanisms
- Sports injuries and prevention
- Traumatic Brain Injury and Neurovascular Disturbances
- Colorectal and Anal Carcinomas
- Cancer-related gene regulation
- Foot and Ankle Surgery
Henan Cancer Hospital
2011-2025
Zhengzhou University
2021-2025
First Affiliated Hospital of Henan University
2024
Second Affiliated Hospital of Luohe Medical College
2023
Air Force Medical University
2022-2023
First Affiliated Hospital of Wenzhou Medical University
2021-2022
Wenzhou Medical University
2021-2022
Xijing Hospital
2020-2022
The Affiliated Yongchuan Hospital of Chongqing Medical University
2019
Chongqing Medical University
2015-2019
BACKGROUND. Current methods for detecting esophageal cancer (EC) are generally invasive or exhibit limited sensitivity and specificity, especially the identification of early-stage tumors.
Background Sleep deprivation (SD) plays a complex role in central nervous system (CNS) diseases. Recent studies indicate that short-term SD can affect the extent of ischemic damage. The aim this study was to investigate whether could stimulate hippocampal neurogenesis rat model global cerebral ischemia/reperfusion (GCIR). Methods One hundred Sprague-Dawley rats were randomly divided into Sham, GCIR and groups based on different durations SD; group three subgroups: GCIR+6hSD*3d-treated,...
Cerebral ischemia (CI) leads to cognitive dysfunction due the loss of hippocampal neurons. Liver X receptors (LXRs), including LXRα and LXRβ isoforms, are critical for neurogenesis, synaptic plasticity, neurodegeneration, cholesterol metabolism. However, potential role LXRs in pathogenesis CI-induced impairment is unclear. Therefore, we investigated effects LXR activation on neurogenesis function mice with CI. C57 were randomized into four groups that included a sham group three treatment CI...
Abstract Objectives Pseudohypoparathyroidism (PHP) comprises a cluster of heterogeneous diseases characterized by hypocalcemia and hyperphosphatemia due to parathyroid hormone (PTH) resistance. PHP type 1B (PHP1B) is caused heterozygous maternal deletions within GNAS or STX16. STX16 exon 2–6 deletion commonly observed in autosomal dominant (AD)-PHP1B, while sporadic PHP1B results from methylation abnormalities differentially methylated regions remains unclear at the molecular level. Case...
Abstract Introduction The present study aims to evaluate the efficacy and safety of apatinib monotherapy or combination therapy for patients with advanced recurrent biliary tract cancer (BTC). Methods Twenty-eight BTC who progressed after prior systemic therapies treated from January 2017 June 2019 were enrolled in this retrospective observational study. primary end point was progression free survival (PFS). Secondary points included overall (OS), objective response rate (ORR), disease...
Sinistral portal hypertension associated with pancreatic pseudocysts - ultrasonography findings: A case report
Background:Lateral malleolus fractures, typically from trauma, sports, or accidents, are common, with supination external rotation (SER) injuries being most prevalent.SER involve complex joint mechanics and often necessitate surgical intervention for instability.This study compares intramedullary nail plate fixation fibula fractures in SER type IV ankle injuries, considering their biomechanical properties influence on fracture healing. Material/Methods:A prospective, randomized was conducted...
Abstract Background Postoperative delirium (POD) is a common complication after cardiac surgery (CS), with symptoms like attention disorders and even delays patients' recovery. Aims To evaluate the impact of preoperative on‐site visits in care unit (CCU) on POD CS. Study Design Patients admitted to CCU extracorporeal CS were included visiting or non‐visiting group according whether they week. The received visit from nurse‐led multidisciplinary team (including nurses physicians) 1 week before...
Background. Human epidermal growth factor receptor 2 (HER2) is a member of the large ErbB family and an important oncogene in many solid tumors. Pyrotinib has been approved for treatment HER2-positive, recurrent, or metastatic breast cancer. However, there are very few clinical studies on pyrotinib other HER2-positive Therefore, more evidence research impendently needed to shepherd pyrotinib-based therapy nonbreast advanced Patients Methods. We performed retrospective analysis tumors...
Gastric cancer (GC) is one of the leading contributors to global malignancies incidence and mortality worldwide. Advanced GC had a relatively poor prognosis. The emerging targeted therapy improved survival prognosis patients. In treatment GC, crizotinib, although an unapproved drug, has shown satisfactory benefits in some cases. A hepatocyte growth factor receptor (MET) amplification patient with extensive abdominal cavity metastasis who was diagnosed as intermediate-low differentiated...
The present study was conducted to evaluate the efficacy and safety of anlotinib as third-line or above therapy for patients with advanced metastatic gastric cancer.Patients cancer who have failed from second-line treatment treated monotherapy combined chemotherapy immunotherapy June 2019 January 2021 in 3 institutions across China were retrospectively analyzed. primary end point progression free survival (PFS). Secondary points included overall (OS), objective response rate (ORR), disease...
Abstract Background The present study aims to evaluate the efficacy and safety of apatinib monotherapy or combination therapy for patients with advanced recurrent biliary tract cancer(BTC). Methods Twenty-eight BTC who progressed after prior systemic therapies treated from January 2017 June 2019 were enrolled in this retrospective observational study. primary end point was progression free survival (PFS). Secondary points included overall (OS), objective response rate (ORR), disease control...
e16009 Background: Numerous studies have shown that immunotherapy has a synergistic effect when combined with targeted drug therapy. Apatinib been proven effective in advanced gastric cancer. Based on these facts and to assess the efficacy safety of programmed death 1 (PD-1) inhibitors apatinib as combination therapy patients (pts) unresectable locally or metastatic diffuse cancer(DGC), retrospective clinical research study was carried out. Methods: Retrospective analysis cohort pts cancer...
Abstract Background Genetic generalized epilepsy (GGE) accounts for nearly one-third of all epilepsies. The feature status epilepticus (SE) in patients with GGE has been rarely studied. We aimed to determine the electroclinical characteristics SE GGE. Methods In this retrospective study, nine were enrolled at Xijing Hospital, Xi’an, China from May 2014 2020. was confirmed by 24-h video-EEG recording. demography, clinical manifestation, brain MRI and pattern analyzed. Results Of seven female....
Objective To investigate the electroclinical, treatment response and prognosis of juvenile absence epilepsy (JAE). Methods Thirty-two patients diagnosed as JAE from Epilepsy Center Xijing Hospital between January 2014 August 2017 were investigated. All them underwent 24-hour video-electroencephalography(EEG) recording. Clinical aspects, electroencephalographic features, antiepileptic drugs (AEPs) received reviewed. The follow-up time was 6-44 months, with an average (18.6±11.6)...
Objective To investigate the electro-clinical features of epilepsy with eye closure sensitivity (ECS). Methods The electroencephalograph database was searched using ECS during half a year period from January to June 2017 in Xijing Hospital. The duration follow-up one year. Results Fifty-one patients diagnosed as were investigated. Patients classified into four syndromes: 33 eyelid myoclonia absences (EMA); 13 juvenile (JME); two generalized tonic-clonic seizure on awakening and...
Abstract Background: Yolk sac tumor (YST), also known as endodermal sinus tumor, is a highly malignant germ cell-derived tumor. As rare disease, the diagnosis, prognostic factors, and optimal management of yolk are difficult. The present study aims to investigate clinicopathological features strategies Results: We retrospectively investigated seventeen patients with in our institute between January 2010 December 2019. median age population was 24 years (range 6–50 years). Most cases were...
An intelligent nursing system for hospital wards is designed. With STM32 as the core and Internet of things technology, can obtain body temperature, heart rate control all facilities in ward by itself through mobile APP. The has advantages simple operation, high accuracy measurement data, stiff stability good real-time performance. It not only realize comprehensive health monitoring patients, but also greatly reduce workload nurses improve work efficiency.