A5028501575- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Ophthalmology and Eye Disorders
- Retinal Imaging and Analysis
- Retinal and Macular Surgery
- Ophthalmology and Visual Impairment Studies
- Ocular Surface and Contact Lens
- Retinal and Optic Conditions
- Facial Rejuvenation and Surgery Techniques
- Cerebral Venous Sinus Thrombosis
- Intraocular Surgery and Lenses
- Connective tissue disorders research
- Corneal Surgery and Treatments
- Sympathectomy and Hyperhidrosis Treatments
- Genetic and Kidney Cyst Diseases
- Peripheral Neuropathies and Disorders
- Healthcare Systems and Reforms
- Medical Imaging and Analysis
- Ocular Infections and Treatments
- Retinal Development and Disorders
- Health and Wellbeing Research
- Ophthalmology and Visual Health Research
- Biomedical Research and Pathophysiology
- Epigenetics and DNA Methylation
Ophthalmology Associates (United States)
2021-2025
Mayo Clinic
2015-2024
WinnMed
2020-2023
Mayo Clinic in Florida
2015-2023
Mayo Clinic in Arizona
2013-2021
University of Minnesota Rochester
2019
University of Iowa
2003
Normal-tension glaucoma (NTG) is a common cause of vision loss.To investigate the role TANK binding kinase 1 (TBK1) gene duplications in NTG to gain insights into causes that occurs at low intraocular pressure (IOP).In this multicenter case-control study, we investigated patients who met criteria for NTG, including glaucomatous optic neuropathy, visual field defects, and maximum recorded untreated IOP 21 mm Hg or less, matched controls. Participants (N = 755) were recruited from Southampton,...
Trabeculectomy is the surgical standard of care for patients with medically refractory glaucoma. The use antimetabolite agents, such as mitomycin, has increased rate complications after trabeculectomy.To determine trabeculectomy-related during a 25-year study.For this retrospective, population-based study, we enrolled residents Olmsted County, Minnesota, who underwent trabeculectomy from January 1, 1985, through December 31, 2010, at Mayo Clinic and Community Hospital. Data were collected...
Ocular hypertension is an important risk factor for the development of primary open-angle glaucoma (POAG). Data from long-term follow-up can be used to inform management patients with ocular hypertension.
This manuscript describes data from an original study, simulating a tele-glaucoma programme in established clinic practice with interdisciplinary team. is ‘real life’ trial of telemedicine approach to see follow-up patient. The goal evaluate the accuracy such detect worsening and/or unstable disease. Such attractive since in-clinic time could be reduced for both patient and provider. study evaluates agreement between in-person remote assessment glaucoma progression.A total 200 adult patients...
Abstract Axenfeld‐Rieger Syndrome (ARS) type 1 is a rare autosomal dominant condition characterized by anterior chamber anomalies, umbilical defects, dental hypoplasia, and craniofacial with Meckel's diverticulum in some individuals. Here, we describe clinically ascertained female of childbearing age ARS for whom clinical targeted sequencing deletion/duplication analysis followed exome genome resulted no pathogenic variants or unknown significance PITX2 FOXC1 . Advanced bioinformatic the...
Health-related quality of life (HRQOL) is often reduced with glaucoma, but associated factors are poorly understood.To determine HRQOL in medically and surgically treated patients glaucoma.Prospective cohort study at a tertiary referral glaucoma practice, 160 consecutive, prospectively enrolled or adult glaucoma.All completed 2 questionnaires (the 25-item National Eye Institute Visual Function Questionnaire the Adult Strabismus-20 questionnaire [AS-20]). Thirty-six had undergone drainage...
<h3>Importance</h3> Mutations in the myocilin (<i>MYOC</i>) gene are most common molecularly defined cause of primary open-angle glaucoma that typically occurs patients with high intraocular pressures (IOP). One<i>MYOC</i>mutation, p.Gln368Ter, has been associated as many 1.6% cases had a mean maximum recorded IOP 30 mm Hg. However, to our knowledge, role p.Gln368Ter mutation normal-tension (NTG) an 21 Hg or lower not investigated. <h3>Objective</h3> To evaluate...
In this longitudinal study of patients with open-angle (OAG), pseudoexfoliative (PXE), or neovascular glaucoma (NVG) receiving drainage devices (GDD), posttube cumulative rates reoperation, corneal graft, and visually threatening complications (VT-complications) increased beyond 5 years were not significantly affected by type.To the need for additional surgery development after first GDD in eyes primary OAG, PXE, NVG glaucoma.There 306 OAG (n=185), PXE (n=60), (n=61) who received a between...
Glaucoma specialists and optometrists who work in a team model at single institution utilize common definition of glaucoma progression treatment algorithm. The purpose this study was to assess the consistency agreement identifying among 1 team.In total, 399 eyes 200 patients age 18 or older with were enrolled over 2 years. Clinical data, disc photographs, optical coherence tomography (OCT), visual fields independently reviewed by masked fellowship-trained specialists. Each eye judged as no...
To determine the effect of a protocol for new physician-led, team-based glaucoma care model implemented in 2008 at Mayo Clinic's campus Rochester, Minnesota (MCR), to increase conformance with American Academy Ophthalmology (AAO) Preferred Practice Pattern guidelines treatment primary open-angle glaucoma.Records 591 patients newly diagnosed were assessed retrospectively completion 9 AAO recommended metrics including measured corneal thickness, intraocular pressure (IOP), cup disk ratio,...
Precis: Diplopia was present in ~20% of patients with Ahmed FP7 (FP7) or Baerveldt 350 (B350), compared 5% to 6% those 250 (B250) controls, suggesting risk diplopia should be included preoperative counseling. Purpose: The purpose this study examine the prevalence and strabismus B250, B350, glaucoma drainage devices (GDD). Materials Methods: In cohort study, 18 years above who had received, would receiving, a GDD, medically treated controls were consecutively enrolled from August 8, 2017,...
Précis: Over 10 years in a tertiary care setting, glaucoma drainage devices (GDDs) have not increased as reason for keratoplasty. Purpose: The purpose of this study was to determine whether the reasons keratoplasty changed between with special attention rate GDDs Methods: Patients aged 18 or above who underwent at Mayo Clinic, Rochester, MN from 2005 2006 and 2015 2016 were studied. All performed time period are assessed, including patients previously had GDD implanted same eye. After...
Anti-vascular endothelial growth factor (VEGF) injections, while used to effectively treat numerous retinal vascular conditions, can be associated with transient and prolonged ocular hypertension. There is minimal literature detailing the development of normal-tension glaucoma (NTG) following intravitreal anti-VEGF injections.A 38-year-old Caucasian male no medical or history was diagnosed an inferior HRVO macular edema in left eye. The patient received a total eleven monthly aflibercept...
Précis: Kaplan-Meier analysis was used to compare the rate of corneal grafting after glaucoma drainage device (GDD) placement in pediatric and adult patients. Adults were at an increased risk receiving a graft placement. Purpose: The goal this study implantation GDD Patients: Patients between January 1, 1985 December 31, 2017 selected from medical records. their first while <18 years age considered children for extent study. Methods: We compared using analysis. Baseline patient...