Marcin Michałek

ORCID: 0000-0002-3762-1201
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Research Areas
  • Cardiovascular Conditions and Treatments
  • Cardiac electrophysiology and arrhythmias
  • Meat and Animal Product Quality
  • Cardiac Arrhythmias and Treatments
  • Nutrition and Health Studies
  • Pharmacological Effects and Assays
  • Atrial Fibrillation Management and Outcomes
  • Cardiac pacing and defibrillation studies
  • Animal Nutrition and Physiology
  • Cardiomyopathy and Myosin Studies
  • Cardiovascular Function and Risk Factors
  • Cardiovascular Effects of Exercise
  • Neurological disorders and treatments
  • Agricultural safety and regulations
  • Cardiac Imaging and Diagnostics
  • Structural Engineering and Materials Analysis
  • Renal and Vascular Pathologies
  • Advancements in Materials Engineering
  • Chemical Thermodynamics and Molecular Structure
  • Kidney Stones and Urolithiasis Treatments
  • Fatty Acid Research and Health
  • Celiac Disease Research and Management
  • Mining and Industrial Processes
  • Coccidia and coccidiosis research
  • Rabbits: Nutrition, Reproduction, Health

Wroclaw University of Environmental and Life Sciences
2015-2024

Military Hospital
2017

Jagiellonian University
2006

AGH University of Krakow
2005

Background. Atherosclerosis and vascular calcifications are common causes of morbidity mortality in maintenance haemodialysis patients. In addition to the well-known traditional risk factors, uraemia-specific factors appear enhance dramatically progression pathological processes involved. The aim present study was evaluate degree atherosclerosis chronic patients using non-invasive imaging methods, identify potentially involved factors. Methods. included 73 (36 females, 37 males), aged 25–75...

10.1093/ndt/gfl564 article EN Nephrology Dialysis Transplantation 2006-09-02

The prevalence of arrhythmias in dogs and the influence sex, breed, age, body weight were analysed over a seven-year span.In total, 1189 referrals for cardiological examination by electrocardiography received at one academic centre Poland between 2008 2014. largest proportion examined cross-breeds with below 25 kg (n = 153, 12.87%), followed German Shepherds 122, 10.26%), Labrador Retrievers 68, 5.72%), Yorkshire Terriers 63, 5.3%), Boxers 60, 5.05%). Retrospective analysis was made 1201...

10.1515/jvetres-2017-0013 article EN cc-by-nc-nd Journal of Veterinary Research 2017-03-01

Dysfunction of heart leads inevitable to the dysfunction kidney which is termed as cardiorenal syndrome (CRS). Previous studies have confirmed existence CRS in dogs with degenerative mitral valve disease (DMVD). The goal study was assess usefulness commercial test measure podocyturia and urine podocine/creatinine ratio (UPoC) an early marker injury. Urine calculated because numbers podocytes dependent on concentration. Fifty divided into three groups: fifteen healthy (control group), twenty...

10.26402/jpp.2019.2.06 article EN PubMed 2019-04-01

Hypertrophic cardiomyopathy is the most common cardiovascular cause of death in cats. Although majority cats remain asymptomatic, some may develop signs chronic heart failure due to diastolic failure, arterial thromboembolism (ATE) or sudden cardiac death. Therefore, it crucial identify individuals that are high risk developing complications before onset life-threatening signs. Oxidative stress imbalance between production and neutralisation reactive oxygen species. Uncontrolled species...

10.1186/s12917-020-2256-3 article EN cc-by BMC Veterinary Research 2020-01-30

Heart failure occurs in increased oxidative stress conditions, which contribute to the progression of pathological changes. Orally or intravenously administered acetylsalicylic acid (ASA, aspirin) is typically used human patients with acute myocardial ischemia. The study an experimental porcine ischemia-reperfusion model evaluate potential cardioprotective effect intracoronary ASA on injury. was evaluated by measuring selected markers levels infarcted and non-infarcted myocardium 14 days...

10.3390/antiox11081432 article EN cc-by Antioxidants 2022-07-23

Although peripheral blood analysis has become increasingly automated, microscopy is the only available method for diagnosis of anisocytosis and poikilocytosis. The aims study were to compare RBC volume data obtained with two different analysers by manual assessment smears this between dogs in various stages heart failure secondary degenerative mitral valvular (DMV) disease. impact diuretic administration on morphology was also assessed.Sixty-eight dogs, 56 DMV disease 12 as healthy controls,...

10.2478/jvetres-2020-0043 article EN cc-by-nc-nd Journal of Veterinary Research 2020-06-01

Atrial fibrillation may potentially contribute to oxidative stress a greater extent than chronic heart failure. The aim of the study was compare serum total antioxidant capacity and enzymatic defence dogs with failure atrial those subjects sinus rhythm healthy controls.A 33 were divided into three groups: (CHF + AF; n = 12), SR; 9), controls (n 12). Serum (TAC), CuZn-superoxide dismutase (SOD) catalase, plasma glutathione peroxidase (GPx) activity determined.SOD TAC significantly lower in...

10.2478/jvetres-2020-0047 article EN cc-by-nc-nd Journal of Veterinary Research 2020-07-28

In recent years, the high sensitivity and specificity of novel miRNA biomarkers have been utilised for early diagnosis treatment monitoring various diseases. Previous reports showed that abnormal expression miR-208 in mice resulted development an aberrant cardiac conduction system consecutive arrhythmias. On other hand, a study on infarcted human heart tissue upregulation miR-208a subjects with ventricular tachyarrhythmias compared to healthy controls. We prospectively investigated -208b...

10.2478/jvetres-2018-0051 article EN cc-by-nc-nd Journal of Veterinary Research 2018-09-01

Pacemaker implantation is the only effective symptomatic treatment for life-threatening bradyarrhythmias. Major complications observed after of cardiac pacemakers include lead dislocation, loss pulse generator function, and inadequate stimulation. The aim this retrospective single-centre study was to analyse indications pacemaker incidence types associated with procedure in dogs treated bradyarrhythmia. analysis included 31 bradyarrhythmia, implanted permanent 1992-2017. list analysed...

10.2478/jvetres-2019-0016 article EN cc-by-nc-nd Journal of Veterinary Research 2019-03-01

Animal nutrition plays an important role in the therapy of many diseases, including heart failure. The aim was to assess whether 6 months feeding AEP + ADH enriched diet (from fish meat) dogs suffering from failure due mitral degeneration impacts dogs' metabolic profile and clinical status. Twenty small breed were included: 50% stage B2 MMVD 50%, C according ACVIM. Dogs randomly divided into two groups. One group receiving a standard diet, second one with EPA DHA meat). All continued receive...

10.3390/ani11123360 article EN cc-by Animals 2021-11-24

Abstract Introduction Electrical cardioversion is a therapeutic procedure used to convert various types of arrhythmias back sinus rhythm. It restore the rhythm in dogs with atrial fibrillation. The effect electrical energy during on red blood cells (RBC) not fully understood. Studies humans reported lysis RBC following cardioversion. Similar studies have been carried out dogs. aim study was assess chosen parameters. Material and Methods 14 large giant breed weighing from 30 84 kg lone...

10.2478/jvetres-2018-0015 article EN cc-by-nc-nd Journal of Veterinary Research 2018-03-01

Precise understanding of the dimensions vascular lumina is essential for accurate interpretation cardiac vessels imaging. To authors' best knowledge, this first study focusing on ultrasound measurement right coronary artery (RCA) in horse. The aim was to determine both ultrasonographic range normal diameter and lumen area RCA horses influence gender, age level training dimensions. An additional assess intra- inter-observer repeatability collected measurements.Thirty-six privately owned,...

10.1186/s12917-019-1792-1 article EN cc-by BMC Veterinary Research 2019-01-28

The presence of an accessory atrioventricular conduction pathway may provide the anatomical basis for some tachyarrhythmias. Persistent tachyarrythmias result in development systolic dysfunction or tachycardiomyopathy and eventual progression to heart failure. In this paper we report successful ablation involved pathogenesis persistent orthodromic reciprocating tachycardia (AVRT) failure a 3-year-old male Labrador retriever. Electrophysiological study radiofrequency (RF) catheter were...

10.21521/mw.5752 article EN Medycyna Weterynaryjna 2017-01-01

Electrocardiography is a method widely applied in diagnosing abnormalities the functioning of heart muscle veterinary medicine. It non-invasive and easy to perform test helpful general examination used patient monitoring during anesthesia. Since 1980s, pigs have become more popular companion animals. Moreover, pig model animal biomedical research. Therefore, there need provide them with higher-quality services, also emergency situations. creates new challenges for veterinarians expand their...

10.1186/s40813-022-00282-x article EN cc-by Porcine Health Management 2022-09-19

Acute myocardial infarction (MI) is one of the most common causes death in humans highly developed countries. Among its frequent complications affecting patient's prognosis are cardiac arrhythmias: ventricular tachycardia (VT) and fibrillation (VF).The study aimed to characterise arrhythmias 19 pigs subjected experimentally induced MI obtained by occlusion proximal left anterior descending (LAD) coronary artery using an angioplasty balloon. The anaesthetic protocol was modified reduce...

10.2478/jvetres-2022-0046 article EN cc-by-nc-nd Journal of Veterinary Research 2022-08-29

The bone tissue destruction during drilling is still one of the crucial problems in implantology. In this study, influence speed, coolant presence, and its temperature on was tested using swine rib as a biological model human jaws. same method (with or without coolant) used all samples. microscopic investigation estimated size zone morphology surrounding canal. achieved results were statistically elaborated. study proved that optimal speed ca. 1200 rpm, but had no significant provoked...

10.3390/app11062493 article EN cc-by Applied Sciences 2021-03-11
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