- Coal Properties and Utilization
- Geoscience and Mining Technology
- Connective Tissue Growth Factor Research
- Tissue Engineering and Regenerative Medicine
- TGF-β signaling in diseases
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Esophageal Cancer Research and Treatment
- Transgenic Plants and Applications
- Coal and Coke Industries Research
- Coal and Its By-products
- Image Enhancement Techniques
- Wound Healing and Treatments
- Metastasis and carcinoma case studies
- Medical Research and Treatments
- Hair Growth and Disorders
- Cell Image Analysis Techniques
- Cancer Genomics and Diagnostics
- Risk and Safety Analysis
- Nicotinic Acetylcholine Receptors Study
- Muscle Physiology and Disorders
- Underwater Vehicles and Communication Systems
- Regional Economic and Spatial Analysis
- Extracellular vesicles in disease
- Robotics and Automated Systems
Xi'an University of Science and Technology
2021-2024
First Affiliated Hospital of Soochow University
2022-2024
Soochow University
2022-2024
Shenyang Pharmaceutical University
2024
Nanyang Technological University
2023
University of Michigan–Ann Arbor
2020-2021
Wannan Medical College
2021
Shanghai Tunnel Engineering Rail Transit Design & Research Institute
2014
Sun Yat-sen University
2001-2008
The First Affiliated Hospital, Sun Yat-sen University
2001-2008
Background Angiogenesis stands as a pivotal hallmark in lung adenocarcinoma (LUAD), intricately shaping the tumor microenvironment (TME) and influencing LUAD progression. It emerges promising therapeutic target for LUAD, affecting patients’ prognosis. However, its role TME, prognosis, clinical applicability remain shrouded mystery. Methods We employed integrated single-cell bulk transcriptome sequencing to unravel heterogeneity of angiogenesis within cells. Through “consensus clustering”, we...
The use of adjuvant chemotherapy (ACT) in completely resected stage IB NSCLC is still controversial. This study aims to investigate the efficacy ACT pathological non-small cell lung cancer (NSCLC) with high risk factors.
The precise mechanism of asiaticoside in molecular and gene expression levels Smad protein mRNA still remains unknown. We hypothesised that might inhibit the formation hypertrophic scarring by affecting interfering with signalling pathway.To investigate effects on scar fibroblasts (HSFs) to clarify treatment.Normal skin HSFs were exposed various concentrations serum-free medium for 72 h, then immunocytochemistry was used examine localization phosphorylated Smad2 Smad7. studied both at...
BACKGROUND Smad proteins are important intracellular mediators of transforming growth factor (TGF)-β signaling. Little has been known about the specific relationship between TGF-β and TGF-β/Smad signaling in hypertrophic scars. OBJECTIVE The objective was to investigate expression Smads METHODS In this study, we initially determined endogenous protein levels Smad2 Smad7 scar fibroblast (HSFs) normal skin (NSFs). Second, stimulated HSFs NSFs with recombinant human TGF-β1 for 24 hours...
It is of great significance to study the characteristics low-temperature oxidation coal in an adiabatic environment for prediction and control spontaneous combustion. Coal combustion experimentation can better simulate field conditions reflect test actual process underlying coal. Numerical simulation methods provide a systematic solution research on dynamic evolution In this study, large-scale bench was employed heating gas generation laws Huangling samples from 303–443 K, revealing...
Abstract The current evidence provides support for the involvement of bone marrow mesenchymal stem cells (BMSCs) in regulation airway epithelial cells. However, a comprehensive understanding underlying biological mechanisms remains elusive. This study aimed to isolate and characterize BMSC‐derived exosomes (BMSC‐Exos) (ECs) through primary culture. Subsequently, impact BMSC‐Exos on ECs was assessed vitro, sequencing analysis conducted identify potential molecular involved these interactions....
In recent years, 3D bioprinting with various types of bioinks has been widely used in tissue engineering to fabricate human tissues and organs appropriate biological functions. Decellularized extracellular matrix (dECM) is an excellent bioink candidate because it enriched a variety bioactive proteins factors can provide suitable environment for repair or regeneration while reducing the likelihood severe immune rejection. this Review, we systematically review advances decellularization...
Consistent cell culture performance is a prerequisite to ensure product quality consistency and achieve productivity goals for the manufacture of recombinant protein therapeutics, including monoclonal antibodies. Here peculiar observation reported where high levels intracellular BiP in seed train cultures are consistently predictive poor subsequent inoculum production antibody produced CHO cells. This investigation suggests that this line triggered by slightly lower pH, which interferes with...
Abstract Background Esophageal carcinosarcoma (ECS) is a rare malignant tumor that often presents as an intraluminal polypoid lesion in the esophageal lumen. The pathogenesis of not clear and its etiology still being discussed. Case presentation We report case 68-year-old male who had dysphagia for approximately three months. Contrast-enhanced computed tomography showed irregular enhancing mass lower esophagus. Endoscopy gray-white with smooth surface almost filled lumen at location 28 cm...
To investigate the influence of moisture on exothermic properties coal oxidation, this study investigated variation in thermal effect and radical parameters oxidation process under different content. This was achieved through thermogravimetric–differential experiments electron spin resonance experiments. Additionally, analyzed impact free radicals characteristics at stages using product–moment correlation method. The results indicate that content 8% is a critical point for promoting or...
Transforming underwater imaging, our integrated neural network and polarization camera enhance PSNR by 40.61%, enabling the robot to effectively discern weak signals in highly scattering environments facilitating swift imaging detection.
As a result of mistake during the figure assembly, in Figure 5A panel DU145/0 h/120 μg/ml NLS was duplication h/60 NLS, and PC3/24 μg/ ml DU145/24 NLS.The corrected 5 appears below as 1.These changes do not affect conclusions article.
Compared to roadways with structured characteristics, sidewalk scenarios in urban environments are often more complex and variable, also easily encountered special unknown challenges. The Continental-NTU Delivery Robotic Platform dataset was constructed provide a class of multimodal sensor information sets that can be used for navigation unstructured environments, validation support decision-making algorithms last-mile delivery robots. the released not only covers 3D LiDAR, camera, inertial...
Coal spontaneous combustion is one of the main disasters that threaten mine safety production., and coal adsorption characteristics cause combustion. Therefore, a lot researchers have begun to pay close attention field research prevent Based on bibliometrics, this paper analyzes number published papers, journal sources, high-yield authors, institutions hotspots in SCI database Web Science platform, makes visual analysis using Citespace software. The shows papers has been rise recent years,...