- Aquaculture disease management and microbiota
- Echinoderm biology and ecology
- Protein purification and stability
- RNA Interference and Gene Delivery
- Aquatic life and conservation
- Virus-based gene therapy research
- Genomics and Phylogenetic Studies
- Invertebrate Immune Response Mechanisms
- Marine and coastal plant biology
- Microfluidic and Bio-sensing Technologies
- Ecology and Vegetation Dynamics Studies
- Monoclonal and Polyclonal Antibodies Research
- Minerals Flotation and Separation Techniques
- Antimicrobial Peptides and Activities
- Mosquito-borne diseases and control
- CRISPR and Genetic Engineering
- Seaweed-derived Bioactive Compounds
- Marine Bivalve and Aquaculture Studies
- Epigenetics and DNA Methylation
- Forest Insect Ecology and Management
- Insect symbiosis and bacterial influences
- Immune Response and Inflammation
- Drug Solubulity and Delivery Systems
- Nanoparticle-Based Drug Delivery
- Identification and Quantification in Food
AbbVie (United States)
2024
State Key Laboratory of Digital Medical Engineering
2024
Hainan University
2024
Hainan Medical University
2024
University of Massachusetts Chan Medical School
2024
Jianghan University
2023
Fujian Fisheries Research Institute
2010-2021
Institute of Plant Protection
2021
Regeneron (United States)
2021
University of Colorado Anschutz Medical Campus
2014-2018
A Raman spectrometer and dynamic light scattering system were combined in a single platform (Raman-DLS) to provide concomitant higher order structural hydrodynamic size data for therapeutic proteins at high concentration. As model proteins, we studied human serum albumin (HSA) intravenous immunoglobulin (IVIG). HSA concentration temperature interval during heating did not affect the onset temperatures conformation perturbation or aggregation. The impact of pH on thermal stability was tested...
The red-spotted grouper Epinephelus akaara (E. akaara) is one of the most economically important marine fish in China, Japan and South-East Asia a threatened species. species also considered good model for studies sex inversion, development, genetic diversity immunity. Despite its importance, molecular resources E. remain limited no reference genome has been published to date. In this study, we constructed chromosome-level by taking advantage long-read single-molecule sequencing de novo...
A fluorogenic aptamer (FA)-based hybridization chain reaction (HCR) could provide a sensitive and label-free signal amplification method for imaging molecules in living cells. However, existing FA-HCR methods usually face some problems, such as complicated design significant background leakage, which greatly limit their application. Herein, we developed an FA-centered HCR (FAC-HCR) based on remote toehold-mediated strand displacement reaction. Compared to traditional HCRs mediated by four...
Urbanization is a pressing challenge for earth's humans because it changing not only natural environments but also agricultural lands. Yet, the consequences of cropland loss on pest insect populations that largely depend these habitats remain unclear. We used 17-year data set to investigate dynamics three moth species (i.e., striped stem borer, yellow and pink borer) their driving forces across largest mega-urban region China. Total abundance declined by about 80%, which was strongly...
Electron impact Sc and V K-shell ionization cross sections have been measured for the first time in incident energy region from near threshold to 45 keV. Thin targets with thick substrates are used experiments. The influence of substrate on data has corrected by a method based upon an electron transport calculation. For elements, experimental compared some empirical formulae theoretical results. It is found that most other elements before (i.e. Ti, Cr, Mn, Fe, Co, Ni, Cu, Zn, Nb Mo) same as...
At present, few morphological descriptions are available for Acentrogobius species and there exist some confused issues on the classification phylogeny. In this study, we first determined described complete mitochondrial genome of sp. The mitogenome sequence is 17 083 bp in length, containing 13 protein-coding genes, two rRNA 22 tRNA a putative control region (CR), light-strand replication origin (OL). overall base composition 28.9% A, 26.2% T, 28.5% C, 16.4% G, with slight AT bias (55.1%)....
Sea cucumber species are abundant (>1400 species) and widely distributed globally. mtDNA sequencing is frequently used to identify the phylogenetic evolutionary relationships among species. However, there no reports on mitochondrial genome of Phyllophorus liuwutiensis . Here, we performed P. examine its with other echinoderms. Its (15 969 bp) contains 37 coding genes, including 13 protein‐coding 22 tRNA genes 2 rRNA genes. Except for one gene ( nad6 ) five encoded negative strand, all...
The aim of this study was to determine the effects Bacillus licheniformis CQN-12, B. amyloliquefaciens CQN-2, and subtilis CQN-39 originally isolated from gut a healthy sea cucumber (Apostichopus japonicus), on growth performance, microbiota immune response cucumbers (A. japonicus). Sea were fed commercial pellet feed supplemented with CQN-2 or at different concentrations (0 (control), 107 109 CFU/g respectively), for 60 days. Our results revealed that dietary CQN-12 (107 optimal...