A5074747392- Advanced MRI Techniques and Applications
- Functional Brain Connectivity Studies
- Advanced NMR Techniques and Applications
- Advanced Chemical Physics Studies
- Atomic and Subatomic Physics Research
- Spectroscopy and Laser Applications
- Neural dynamics and brain function
- MRI in cancer diagnosis
- Atmospheric Ozone and Climate
- Lanthanide and Transition Metal Complexes
- Photoreceptor and optogenetics research
- Wireless Power Transfer Systems
- Advanced Sensor and Energy Harvesting Materials
- Photochemistry and Electron Transfer Studies
- Polysaccharides and Plant Cell Walls
- Transcranial Magnetic Stimulation Studies
- Energy Harvesting in Wireless Networks
- Advanced biosensing and bioanalysis techniques
- EEG and Brain-Computer Interfaces
- Polysaccharides Composition and Applications
- Spectroscopy and Quantum Chemical Studies
- Solid-state spectroscopy and crystallography
- Protease and Inhibitor Mechanisms
- Atmospheric chemistry and aerosols
- Electron Spin Resonance Studies
Michigan State University
2016-2025
Tsinghua University
2021-2025
Michigan United
2024
University of Utah
2023
Portland State University
2023
TU Wien
2023
Yale University
2023
Meta (United States)
2023
University of Arkansas at Fayetteville
2023
Beijing University of Technology
2018-2020
Abstract Extensive in vivo imaging studies investigate the hippocampal neural network function, mainly focusing on dorsal CA1 region given its optical accessibility. Multi-modality fMRI with simultaneous electrophysiological recording reveal broad cortical correlation patterns, but detailed spatial functional map remains lacking limited resolution. In particular, hemodynamic responses linked to specific activity are unclear at single-vessel level across vasculature, which hinders deciphering...
The field of soft robotics has seen increasing interest and developments in recent years. Stiffness tuning is a desirable characteristic for robots since it enables adaptively modulating the load-bearing capability, shape, locomotion behavior robots. In this article compact cost-effective mechanism stiffness proposed based on three-dimensional printed conductive polylactic acid (CPLA) material, its potential demonstrated through pneumatic actuator (SPA) capable shape modulation. particular,...
Abstract Tumor heterogeneity is one major reason for unpredictable therapeutic outcomes, while stratifying responses at an early time may greatly benefit the better control of cancer. Here, we developed a hybrid nanovesicle to stratify radiotherapy response by activatable inflammation magnetic resonance imaging (aiMRI) approach. The high Pearson’s correlation coefficient R values are obtained from correlations between T 1 relaxation changes 24–48 h and ensuing adaptive immunity ( = 0.9831)...
As an important anticancer drug, chlormethine has been used for more than 70 years. Owing to its good efficacy and adaptable structure, integrated with trackable prodrugs, the investigation of drug control tumor targeting. Given increasing importance precision medicine, this review we collate structure–activity strategies chlormethine-based prodrugs: 1) Small molecule structural transformation closed spiropyran (SP) zwitterionic merocyanin (MC), intramolecular charge transfer (ICT),...
Atherosclerosis is associated with inflammation in the arteries. Hyaluronan atorvastatin nanoparticle conjugate could target CD44 overexpressed atherosclerotic plaques and significantly reduce plaque inflammation.
With the development of on-chip learning processors for edge-AI applications, energy efficiency NN inference and training is more critical. As dominates consumption [1], [2], [4], [5], reduction paramount importance. Spiking neural networks (SNNs) offer energy-efficient compared with convolutional (CNNs) or deepneural (DNNs), but SNN-based have three challenges that need to be addressed (Fig. 22.6.1). 1) During training, some factors involved in ΔW computation are zeros resulting ΔW=O,...
We report detailed vibrational, rotational, and electronic (V, R, E) distributions of nascent NO(X 2Π) deriving from monoenergetic unimolecular reactions jet-cooled NCNO. Excitation is via the à 1A″ ← X̃ 1A′ system above dissociation threshold (17 085±5 cm−1), vibrational predissociation occurs following radiationless decay initially excited state. These results are combined with data on corresponding CN(X 2Σ+) V, R distributions, thereby providing a complete description energy partitioning...
Reducing learning energy consumption is critical to edge-artificial intelligence (AI) processors with on-chip since dominates consumption, especially for applications that require long-term learning. To achieve this goal, we optimize a neuromorphic algorithm and propose random target window (TW) selection, hierarchical update skip (HUS), asynchronous time step acceleration (ATSA) reduce the power consumption. Our approach results in 28-nm 1.25-mm <inline-formula...
The electronic absorption spectrum of NOCl in the region 620–180 nm is assigned by using vector properties NO photofragment and results ab initio calculations at CI level. In assigning spectrum, we take into account recoil anisotropy, rotational alignment, Λ-doublet populations NO, as well calculated vertical excitation energies, oscillator strengths, nature orbitals involved transitions. experiments, use expansion-cooled samples measure anisotropy parameters from Doppler profiles selected A...
BackgroundTwenty million Americans suffer from peripheral nerve injury. These patients often develop chronic pain and sensory dysfunctions. In the past decade, neuroimaging studies showed that these changes are associated with altered cortical excitation-inhibition balance maladaptive plasticity. We tested if neuromodulation of deprived cortex could restore balance, whether it would be effective in alleviating complications.ObjectiveWe non-invasive repetitive transcranial magnetic...
To assess the feasibility of imaging deep-lying internal organs at high spatial resolution by kidney glomeruli in a rodent model with use newly developed, wireless amplified nuclear magnetic resonance (MR) detector.This study was approved Animal Care and Use Committee National Institutes Health/National Institute Neurologic Disorder Stroke. As preclinical demonstration this new detection technology, five different millimeter-scale MR detectors configured as double frequency resonators were...
Matrix metalloproteases (MMPs) have been found to be highly expressed in a variety of malignant tumor tissues. Noninvasive visualization MMP activity may play an important role the diagnosis associated diseases. Here we report design and synthesis set fluorine-19 dendron-based magnetic resonance imaging (MRI) probes for real-time MMP-2 activity. The following features: (a) symmetrical fluorine atoms; (b) number atoms can increased through facile chemical modification; (c) readily accessible...
Atherosclerosis is an inflammatory disease of arterial walls and the rupturing atherosclerotic plaques a major cause heart attack stroke. Imaging techniques that can enable detection before clinical manifestation are urgently needed. Magnetic resonance imaging (MRI) powerful technique to image morphology plaques. In order better analyze molecular processes in plaques, contrast agents selectively bind plaque receptors will prove invaluable. CD44 cell surface protein overexpressed tissues,...
Angular distributions of state-selected NO and O products in the photoinitiated unimolecular decomposition jet-cooled NO2 have been measured by using both photofragment ion imaging technique with velocity map time-of-flight translational spectroscopy. The recoil anisotropy parameter photofragments, β, depends strongly on rotational angular momentum photoproduct. O(3Pj=2,0) are recorded at photolysis wavelengths 371.7, 354.7, 338.9 nm. At these wavelengths, respectively, vibrational levels...
Hyperpolarized magnetic resonance imaging (MRI) contrast agents are revolutionizing the field of biomedical imaging. Xe-129 was recently FDA approved as an inhalable MRI agent for functional lung sensing. Despite success in research settings, modern hyperpolarizers expensive (up to $1M), large, and complex site operate. Moreover, sensing requires specialized hardware that is not commonly available on clinical scanners. Here, we demonstrate proton-hyperpolarized propane gas can be produced...