A5101464948- Ovarian cancer diagnosis and treatment
- Selenium in Biological Systems
- Gestational Trophoblastic Disease Studies
- Natural product bioactivities and synthesis
- Receptor Mechanisms and Signaling
- Molecular Biology Techniques and Applications
- Genomics, phytochemicals, and oxidative stress
- Glutathione Transferases and Polymorphisms
- Power Systems and Technologies
- Cancer-related molecular mechanisms research
- Smart Grid and Power Systems
- Cancer Immunotherapy and Biomarkers
- Gene expression and cancer classification
- Prenatal Screening and Diagnostics
- Power Systems and Renewable Energy
- Synthetic Aperture Radar (SAR) Applications and Techniques
- Medical and Biological Ozone Research
- Medicinal Plant Pharmacodynamics Research
- Dendrimers and Hyperbranched Polymers
- Magnesium in Health and Disease
- Intraperitoneal and Appendiceal Malignancies
- Sesquiterpenes and Asteraceae Studies
- Medicinal Plants and Bioactive Compounds
- Cultural Industries and Urban Development
- Bacterial biofilms and quorum sensing
China Medical University
2013-2024
Shaanxi University of Chinese Medicine
2021-2024
Weifang People's Hospital
2024
Quzhou University
2023-2024
Kunming Medical University
2023
Hebei General Hospital
2023
Anhui Medical University
2019-2022
National Institute of Metrology
2022
Chongqing University
2022
Ministry of Education of the People's Republic of China
2022
Following the 2019 coronavirus disease (COVID-19) outbreak in China, undergraduate students may experience psychological changes. During emergency circumstances, social support is an important factor influencing mental health condition among Shaanxi province. This study aims to find factors associated with symptoms of depression, anxiety, and stress province during COVID-19 pandemic China. A cross-sectional was conducted from Feb 23 Mar 7, 2020. total 1278 universities located participated...
Breast cancer (BC) is a highly heterogeneous disease, and although immunotherapy has recently increased patient survival in number of solid hematologic malignancies, most BC subtypes respond poorly to immune checkpoint blockade therapy (ICB). B cells, particularly those that congregate tertiary lymphoid structures (TLS), play significant role antitumour immunity. However, B-cell heterogeneity at single-cell resolution its clinical significance with TLS need be explored further.Primary tumour...
Thanks to the excellent feature representation capabilities of neural networks, target detection methods based on deep learning are now widely applied in synthetic aperture radar (SAR) ship detection. However, multi-scale variation, small targets with complex background such as islands, sea clutter, and inland facilities SAR images increase difficulty for To performance, this paper, a novel network detection, termed attention-guided balanced pyramid (A-BFPN), is proposed better exploit...
Background: The associations of the consumption cruciferous vegetables (CVs) and their bioactive components, isothiocyanates (ITCs), with ovarian cancer (OC) mortality have been unclear, owing to limited studies inconsistent findings. To date, no evaluated these among Chinese patients OC. This study aims provide more evidence indicating relationships pre-diagnosis CVs ITC intake OC survival. Methods: We examined CV in a hospital-based cohort (n = 853) epithelial between 2015 2020....
The relationships between pre-diagnosis meat intake and ovarian cancer survival were limited controversial. To date, no study has taken account of cooking methods. Thus, we aimed to firstly clarify these associations based on the Ovarian Cancer Follow-Up Study.
To study the effect of Rhodiola Rosea injection on cardiac function and reninangiotensin- aldosterone system (RASS) in rats with chronic heart failure.Rhodiola injection, a traditional Chinese medication for relieving blood stasis improving circulation, is an excellent therapeutic treating coronary disease-angina pectoris. injection's major component, salidroside, protects cardiovascular system. But there isn't much first-hand evidence about how injectable affects failure.In this study, rat...
Background: Dairy product consumption is associated with ovarian cancer (OC) incidence. However, limited evidence available on its influence OC mortality. Methods: The association between pre-diagnostic dairy intake and mortality was investigated in the follow-up study, which included a hospital-based cohort (n = 853) of women diagnosed epithelial 2015 2020. Pre-diagnosis diet information collected using validated food frequency questionnaire. Deaths were ascertained up to March 31, 2021 via...
We investigated the association between peroxiredoxin III (PRX III) and chemotherapy resistance in ovarian cancer. Patient's specimens were taken at time of surgery. Determination is based on whether first diagnosis relapse occurred within 6 months after cessation chemotherapy. PRX expression was immunohistochemically determined paraffin-embedded from platinum-resistant (Pt-resistant) platinum-sensitive (Pt-sensitive) patients. The Pt-resistant group had significantly higher protein compared...
Fatty acid of the root medicinal plant Bupleurum Chinense DC in China has been investigated by gas chromatography combined with mass spectroscopy. After methyl-esterification, eight fatty compositions were identified GC-MS. A simple and rapid determination firstly developed GC-FID. The derivatization condition was order to validate this method. Palmitic acid, palmitoleic oleic linoleic analyzed simultaneously internal standard validity method examined both experimentally good recovery,...
Abstract The volatile composition of the root oils ten Bupleurum species (B.chinense DC., B.scorzonerifolium Willd., B.microcephalum Diels., B.malconense Shan et Y. Li, B.longicaule Wall. DC. var. giraldii Wolff, B.marginatum ex DC, B.bicaule Helm, B.yinchowense B.wenchuanense B.smithii Wolff. parvifolium Li) have been studied. were collected in their typical habitats China. obtained by hydrodistillation and analyses performed GC/FID GC/MS. Fifty constituents identified. major components oil...
5512 Background: Paz, an oral multikinase inhibitor of VEGF, PDGF and c-Kit has showed activity in advanced ovarian cancer. This study evaluated paz as maintenance therapy Asian women with Methods: Subjects FIGO stage II, III, or IV ovarian, fallopian tube, primary peritoneal cancer whose disease had not progressed after debulking surgery followed by chemotherapy were randomized 1:1 to 800 mg once daily placebo for up 24 months. Primary endpoint was PFS RECIST v1.0 based on visit date. If a...
Post-marketing surveillance of antineoplastic agents is performed to evaluate the efficacy and safety in patients aiming at expanding drug indications discovering potential adverse events. The real-world data fraught with missing values. Literature addressing different strategies for dealing such a situation scarce. Using machine learning (ML) algorithms predicting therapeutic outcomes PD-1/PD-L1 Inhibitors has attracted attention. However, training predictive model usually requires imaging...
A simple and rapid capillary gas chromatographic (CGC) method with flame ionization detection has been newly developed for analysis of the essential oil from Radix Bupleuri. Twenty components were identified chromatography-mass spectrometry. E-2-heptenal, furan, 2-pentyl, E-2-nonenal quantified simultaneously using internal standard method. Decane was used as an standard. Separation quantification achieved on a DB-5 column (30 m×0.25 mm i. d., 0.25-μm film thickness). The oven temperature...
Abstract DNA methylation markers in the peripheral blood are able to be applied treat epithelial cancer. Nevertheless, diagnostic potential value of it for ovarian cancer (OV) has not been studied. The study aimed explore difference between OV patients and healthy women. Firstly, whole data was provided by Gene Expression Omnibus (GEO) database. linear model identification significantly differentially expressed methylated CpG sites (differentially [DMP]), further screen co‐expression...
Polyamidoamine dendrimer (PAMAM) is a new nanometer material, which can transfer the target genes to cells with high efficiency and lower toxicity. This study aims evaluate antitumor effects of survivin antisense oligonucleotide (survivin-asODN) (carried by polyamidoamine liposome) on hepatic cancer in nude mice. Hepatic model was established injecting SMMC-7721 subcutaneously into flanks liposome were mixed survivin-asODN, respectively. The shape size complex observed transmission electron...
Colour space has been widely used in digital image processing, but its selection is rarely discussed hashing. Aiming at this problem, we discuss colour by evaluating classification performances of typical hashing algorithms under YCbCr space, CIE L*a*b* HSV and HSI space. Our contributions are two sides. (1) We find that the regularly cannot reach desirable performance outperforms other spaces. (2) analyse D-DCT hashing, NMF-NMF-SQ RT-DCT GF-LVQ different spaces, which first reports these...
Accurate determination of vitamin B12 (VB12) in food matrices remains a big challenge due to the instability VB12 and extreme complexity various matrices. Both matrix effect recovery are main parameters, which needed be evaluated meticulously measurement. An ultra-high performance liquid chromatography coupled quadrupole Q-Exactive Plus orbitrap mass spectrometry (UHPLC-QE-Orbitrap-MS) has been developed detect infant formulas. Besides, four calibration methodologies, including standard...
Toripalimab as a novel PD-1 inhibitor has presented its promising efficacy in patients who developed chemo-refractory carcinomas, whereas no study ever investigated the effectiveness of toripalimab chemo-resistant choriocarcinoma. Here we reported and safety data 4 with choriocarcinoma underwent antibody therapy by individualized chemotherapies. From January 2019 to August 2020, were admitted Shengjing Hospital China Medical University. The patients' age ranged from 29 52 years median 36...