M. Carmen Carmona-García
A5010612782- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Colorectal Cancer Screening and Detection
- Chronic Disease Management Strategies
- Global Cancer Incidence and Screening
- Inflammatory Biomarkers in Disease Prognosis
- Colorectal Cancer Treatments and Studies
- Genetic factors in colorectal cancer
- Colorectal Cancer Surgical Treatments
- Cancer Immunotherapy and Biomarkers
- Long-Term Effects of COVID-19
- Frailty in Older Adults
- Breast Cancer Treatment Studies
- COVID-19 and Mental Health
- Digital Radiography and Breast Imaging
- Gastric Cancer Management and Outcomes
- Colorectal and Anal Carcinomas
- Intensive Care Unit Cognitive Disorders
- Breast Lesions and Carcinomas
- Cancer Risks and Factors
- Nutrition and Health in Aging
- Neuroendocrine Tumor Research Advances
- Childhood Cancer Survivors' Quality of Life
- Economic and Financial Impacts of Cancer
- Lung Cancer Diagnosis and Treatment
Institut Català d'Oncologia
2019-2023
Hospital Universitari de Girona Doctor Josep Trueta
2018-2023
Institut d'Investigació Biomèdica de Girona
2018-2021
Government of Catalonia
2019-2020
Clínica Girona
2016-2019
University of Girona
2018
Biomedical Research Institute
2018
Abstract The SARS-CoV-2 pandemic significantly affected oncology practice across the globe. There is uncertainty as to contribution of patients' demographics and oncologic features severity mortality from COVID-19 little guidance role anticancer anti–COVID-19 therapy in this population. In a multicenter study 890 patients with cancer confirmed COVID-19, we demonstrated worsening gradient breast hematologic malignancies showed that male gender, older age, number comorbidities identify subset...
Whether the severity and mortality of COVID-19 in patients with cancer have improved terms disease management capacity is yet to be defined.To test whether from among during course pandemic.OnCovid a European registry that collects data on consecutive solid or hematologic COVID-19. This multicenter case series study included real-world 35 institutions across 6 countries (UK, Italy, Spain, France, Belgium, Germany). update diagnosed between February 27, 2020, February, 14, 2021. Inclusion...
Background Patients with cancer are particularly susceptible to SARS-CoV-2 infection. The systemic inflammatory response is a pathogenic mechanism shared by progression and COVID-19. We investigated inflammation as driver of severity mortality from COVID-19, evaluating the prognostic role commonly used indices in SARS-CoV-2-infected patients accrued OnCovid study. Methods In multicenter cohort Europe, we evaluated dynamic changes neutrophil:lymphocyte ratio (NLR); platelet:lymphocyte (PLR);...
BackgroundNumerous studies have analysed the effect of comorbidity on cancer outcomes, but evidence association between multimorbidity and short-term mortality among colorectal patients is limited. We aimed to assess this most frequent patterns associated with a higher risk in Spain.MethodsData were obtained from two Spanish population-based registries electronic health records. estimated unadjusted cumulative incidence death by status at 6 months 1 year. used flexible parametric model...
Cancer treatment and outcomes can be influenced by tumor characteristics, patient overall health status, comorbidities. While previous studies have analyzed the influence of comorbidity on cancer outcomes, limited information is available regarding factors associated with increased prevalence comorbidities multimorbidity among patients colorectal in Spain.This cross-sectional study obtained data from all cases diagnosed two Spanish provinces 2011 population-based registries electronic...
Rectal cancer is a common and serious disease. The aim of the SUDCAN collaborative study was to compare net survival from rectal between six European Latin countries (Belgium, France, Italy, Portugal, Spain, Switzerland) provide trends in dynamics excess mortality rates up 5 years after diagnosis. data were extracted EUROCARE-5 database. First, studied over period 2000-2004 using Pohar-Perme estimator. For trend analyses, study-period specific each country. results are reported 1992 2004...
Abstract Background: We aimed to evaluate survival and disease-free in different subtypes of interval cancers by breast density, taking into account clinical biological characteristics. Methods: included 374 invasive tumors (195 screen-detected cancers; 179 cancers, classified true interval, false-negatives, occult minimal-sign cancers) diagnosed women ages 50–69 years undergoing biennial screening from 2000–2009, followed up 2014. Breast density was categorized non-dense (<25% dense...
Colorectal cancer (CRC) is the third most common worldwide. Population-based, high-resolution studies are essential for continuous evaluation and updating of diagnosis treatment standards. This study aimed to assess adherence clinical practice guidelines investigate its relationship with survival. We conducted a retrospective population-based 1050 incident CRC cases from registries Granada Girona, 5-year follow-up. recorded clinical, diagnostic, treatment-related information assessed nine...
(1) Background: We investigated the incidence and survival trends for pancreatic cancer (PC) over last 25 years in Girona region, Catalonia, Spain; (2) Methods: Data were extracted from population-based Cancer Registry. Incident PC cases during 1994–2015 classified using International Classification of Diseases Oncology Third Edition (ICD-O-3). Incidence rates age-adjusted to European standard population (ASRE) world (ASRW) obtained. Trends assessed estimated annual percentage change (EAPC)...
Abstract Background We aimed to identify the risk factors associated with early, late and long-term readmissions in women diagnosed breast cancer participating screening programs. Methods performed a multicenter cohort study of 1055 aged 50–69 years Spanish programs, between 2000 2009, followed up 2014. Readmission was defined as hospital admission related disease and/or treatment complications, classified early (< 30 days), (30 days-1 year), or readmission (> 1 year). used logistic...
Abstract Colorectal cancer is the second most frequently diagnosed in Spain. Cancer treatment and outcomes can be influenced by tumor characteristics, patient general health status comorbidities. Numerous studies have analyzed influence of comorbidity on outcomes, but limited information available regarding frequency distribution comorbidities colorectal patients, particularly elderly ones, Spanish population. We developed a population-based high-resolution cohort study all incident cases...
Background . Our aim was to assess the role of breast density on cancer mortality and recurrences, considering patient tumour characteristics treatments received among women attending population-based screening programmes. Methods We conducted a retrospective cohort study aged 50–69 years programmes, diagnosed with invasive between 2000 2009, followed up 2014. Breast categorised as low (≤25% dense tissue), intermediate (25–50%), high (≥50%). Cox proportional hazards regression models were...
COVID-19 pathophysiology is caused by a cascade of respiratory and multiorgan failures arising, at least in part, from the SARS-CoV-2-driven dysregulation master transcriptional factor STAT3. Pharmacological correction STAT3 over-stimulation, which root acute distress syndrome (ARDS) coagulopathy/thrombosis events, should be considered for treatment severe COVID-19. In this perspective, we first review current body knowledge on role pathogenesis We then exemplify potential clinical value...
<p>Supplementary Tables and Figures</p>
<div>Abstract<p>The SARS-CoV-2 pandemic significantly affected oncology practice across the globe. There is uncertainty as to contribution of patients' demographics and oncologic features severity mortality from COVID-19 little guidance role anticancer anti–COVID-19 therapy in this population. In a multicenter study 890 patients with cancer confirmed COVID-19, we demonstrated worsening gradient breast hematologic malignancies showed that male gender, older age, number...
<p>Supplementary Tables and Figures</p>
<div>Abstract<p>The SARS-CoV-2 pandemic significantly affected oncology practice across the globe. There is uncertainty as to contribution of patients' demographics and oncologic features severity mortality from COVID-19 little guidance role anticancer anti–COVID-19 therapy in this population. In a multicenter study 890 patients with cancer confirmed COVID-19, we demonstrated worsening gradient breast hematologic malignancies showed that male gender, older age, number...
Abstract We sought to determine parameters of the acute phase response, a feature innate immunity activated by infectious noxae and cancer, deranged Covid-19 establish oncological indices’ prognostic potential for patients with concomitant cancer Covid-19. Between 27/02 23/06/2020, OnCovid retrospectively accrued 1,318 consecutive referrals aged 18 from U.K., Spain, Italy, Belgium, Germany. Patients myeloma, leukemia, or insufficient data were excluded. The neutrophil-lymphocyte ratio (NLR),...
Abstract Background. Systemic inflammation is a pathogenic mechanism shared by infection and cancer. Mortality from Covid-19 strongly linked to systemic cytokine excess. We investigated as driver of severity in patients with Methods. Between 27/02 23/06/2020, OnCovid retrospectively accrued 1,318 consecutive European cancer Covid-19. Patients myeloma, leukemia, or insufficient data were excluded. The neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte (PLR), prognostic nutritional index...