A5021438276- DNA Repair Mechanisms
- Photosynthetic Processes and Mechanisms
- Chromosomal and Genetic Variations
- Plant Molecular Biology Research
- Plant Reproductive Biology
- Carcinogens and Genotoxicity Assessment
- Microtubule and mitosis dynamics
- Ziziphus Jujuba Studies and Applications
- Plant Genetic and Mutation Studies
- Caching and Content Delivery
- Genomics and Phylogenetic Studies
- Genomics and Chromatin Dynamics
- Plant Parasitism and Resistance
- Protist diversity and phylogeny
- Advanced Data Storage Technologies
- Mitochondrial Function and Pathology
- Ammonia Synthesis and Nitrogen Reduction
- Plant and Fungal Interactions Research
- Agriculture, Soil, Plant Science
- Plant Disease Resistance and Genetics
- Plant Gene Expression Analysis
- Genetic Mapping and Diversity in Plants and Animals
- Plant tissue culture and regeneration
- Plant Virus Research Studies
- MicroRNA in disease regulation
Institute of Genetics and Developmental Biology
2016-2024
Institute of Botany
2019-2024
Chinese Academy of Sciences
2016-2024
Alibaba Group (China)
2022
State Key Laboratory of Plant Genomics
2016-2021
Jilin University
2021
Center for Excellence in Molecular Plant Sciences
2020
Hebei Agricultural University
2011
In higher eukaryotes, heterochromatin is mainly composed of transposable elements (TEs) silenced by epigenetic mechanisms. But, the silencing certain heterochromatin-associated TEs disrupted heat stress. By comparing genome-wide high-resolution chromatin packing patterns under normal or conditions obtained through Hi-C analysis, we show here that stress causes global rearrangement 3D genome in Arabidopsis thaliana. Contacts between pericentromeric regions and distal chromosome arms, as well...
Abnormal temperature caused by global climate change threatens the rice production. Defense signaling network for chilling has been uncovered in plants. However, less is known about repairing DNA damage produced from overwhelmed defense and its evolution during domestication. Here, we genetically identified a major QTL, COLD11 , using data-merging genome-wide association study based on an algorithm combining polarized data two subspecies, indica japonica into one system. Rice...
Telomere bouquet formation, a highly conserved meiotic event, plays an important role in homologous pairing and therefore progression of meiosis; however, the underlying molecular mechanism remains largely unknown. Here, we identified ZYGOTENE1 (ZYGO1), novel F-box protein rice (Oryza sativa), verified its essential formation during early meiosis. In zygo1 mutants, zygotene chromosome aggregation telomere clustering failed to occur. The suppressed aberration meiosis1 (pair1) completion...
Significance The programmed double-strand break (DSB) formation is a prerequisite for homologous recombination. synaptonemal complex (SC), known as the meiotic-specific proteinaceous structure, provides an appropriate framework Both are indispensable in meiosis. p31 comet has been proved to play essential role metaphase-to-anaphase transition during mitosis by indirectly activating anaphase-promoting complex/cyclosome status, but underlying function meiosis remains elusive. Here, we...
Summary Nitrogen is one of the most important nutrient element that essential for plant growth and development. Many genes have been reported to contribute nitrogen absorption transportation. However, involved in reutilization are seldom reported. Ornithine δ‐aminotransferase (δ OAT ) enzyme connecting arginine cycling proline cycling. Here, we found Os , homologue δ rice, through mediating arginase activity. In Osoat mutant, metabolic abnormality induced by deficiency floret causes...
Summary In angiosperms, the key step in sexual reproduction is successful acquisition of meiotic fate. However, molecular mechanism determining fate remains largely unknown. Here, we report that OsSPOROCYTELESS (OsSPL) critical for entry rice ( Oryza sativa ). We performed a large‐scale genetic screen sterile mutants aimed to identify genes regulating and identified Os SPL using map‐based cloning. showed meiosis‐specific callose deposition, chromatin organization, centromere‐specific histone...
The organization of microtubules into a bipolar spindle is essential for chromosome segregation. Both centrosome and chromatin-dependent assembly mechanisms are well studied in mouse, Drosophila melanogaster, Xenopus oocytes; however, the mechanism plant meiosis remains elusive. According to our observations microtubule Oryza sativa, Zea mays, Arabidopsis thaliana, Solanum lycopersicum, we propose that key step correction multipolar at metaphase I. spindles failed transition ones OsmtopVIB...
The bipolar spindle structure in meiosis is essential for faithful chromosome segregation. PUTATIVE RECOMBINATION INITIATION DEFECT 1 (PRD1) previously has been shown to participate the formation of DNA double strand breaks (DSBs). However, role PRD1 meiotic assembly not elucidated. Here, we reveal by both genetic analysis and immunostaining technology that involved rice (Oryza sativa) meiosis. We show DSB are disturbed prd1 meiocytes. signals display a dynamic pattern localization from...
Summary Meiotic recombination is closely linked with homologous pairing and synapsis. Previous studies have shown that HOMOLOGOUS PAIRING PROTEIN2 (HOP2), plays an essential role in However, the mechanism by which HOP 2 regulates crossover ( CO ) formation has not been elucidated. Here, we show Os mediates maturation of s promoting synapsis rice Oryza sativa meiosis. We used a combination genetic analysis, immunolocalization super‐resolution imaging to analyze function showed full‐length...
Electrocatalytic nitrogen reduction reaction (NRR) at ambient conditions is a promising route for ammonia (NH3) synthesis but still suffers from low activity and selectivity. Here, ultrafine Sn nanoparticles (NPs) grown on carbon blacks (SnSC/C) have been synthesized through wet-chemical method using sodium citrate dehydrate as stabilizing agent. Benefiting the small sizes of NPs, SnSC/C catalyst exhibits excellent electrocatalytic performance NRR with high Faradaic efficiency 22.76% an NH3...
Replication protein A (RPA), a single-stranded DNA-binding protein, plays essential role in homologous recombination. However, because deletion of RPA causes embryonic lethality mammals, the exact function meiosis remains unclear. In this study, we generated an rpa1a mutant using CRISPR/Cas9 technology and explored its rice (Oryza sativa) meiosis. rpa1a, 12 bivalents were formed at metaphase I, just like wild-type, but chromosome fragmentations consistently observed anaphase I. Fluorescence...
Plant architecture is a main determinate of crop yield, and lateral branching significantly influences the number inflorescences seeds. The mechanism axillary bud initiation remains unclear. This work aimed to examine how miRNAs regulate initiation. By constructing small RNA library screening mutant population, we revealed buds specifically induced by miR394 repressed its target, LEAF CURLING RESPONSIVENESS (LCR). Using promoter-driven fluorescent tags in situ hybridization, showed that...
The repair of SPO11-dependent double-strand breaks (DSBs) by homologous recombination ensures the correct segregation chromosomes. In yeast and human, RAD17 is involved in DNA damage checkpoint control DSB repair. However, little known about its function plants. this study, we characterized homolog rice. Osrad17 pollen mother cells (PMCs), associations between non-homologous chromosomes chromosome fragmentation were constantly observed. These aberrant dependent on formation programmed DSBs....
<title>Abstract</title> The plant architecture is a main determinate of crop yield, and lateral branching significantly influences the number inflorescences seeds. Axillary buds support branch growth, development axillary includes two stages, initiation outgrowth. Extensive studies on outgrowth stage have uncovered fine regulatory mechanisms while our understanding bud remains unclear. This work aims to study how miRNA regulate initiation. By constructing small RNA library screening mutant...
With the rapid growth of cloud computing, efficient management multi-tenant databases has become a vital challenge for service providers. It is particularly important Alibaba, which hosts distributed database supporting one world's largest e-commerce platforms. serves tens millions sellers as tenants, and supports transactions from hundreds buyers. The inherent imbalance shopping preferences buyers essentially generates drastically skewed workload on database, could create unpredictable...