A5066714559- Thyroid Cancer Diagnosis and Treatment
- Thyroid and Parathyroid Surgery
- Head and Neck Anomalies
- Pituitary Gland Disorders and Treatments
- BRCA gene mutations in cancer
- Hepatitis C virus research
- Growth Hormone and Insulin-like Growth Factors
- Thyroid Disorders and Treatments
- Adrenal and Paraganglionic Tumors
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Treatment of Major Depression
- Cardiovascular Function and Risk Factors
- Suicide and Self-Harm Studies
- Cardiac Imaging and Diagnostics
- Liver Disease Diagnosis and Treatment
- Bipolar Disorder and Treatment
- Neuroendocrine Tumor Research Advances
- Cancer Risks and Factors
- Pancreatic and Hepatic Oncology Research
- Cardiac Arrhythmias and Treatments
- Hip and Femur Fractures
- Glutathione Transferases and Polymorphisms
- Lipid metabolism and disorders
- Gastrointestinal Bleeding Diagnosis and Treatment
- Mechanisms of cancer metastasis
Myongji Hospital
2023-2024
Hanyang University
2023-2024
Samsung Medical Center
2015-2023
Sungkyunkwan University
2015-2023
Yonsei University
2023
Wonju Severance Christian Hospital
2023
Asan Medical Center
2022
Hy-Line (United States)
2007-2008
Background: Telomerase reverse transcriptase (<i>TERT</i>) promoter mutations are associated with increased recurrence and mortality in patients thyroid carcinoma. Previous studies on <i>TERT</i> were retrospectively conducted a limited number of patients.Methods: We prospectively collected data all consecutive who underwent carcinoma surgery between January 2019 December 2020 at the Samsung Medical Center, Seoul, Korea. included 2,092 carcinoma.Results: Of patients,...
Follicular thyroid carcinoma (FTC) has different clinicopathological characteristics than papillary carcinoma. However, there are no independent systems to predict cancer-specific survival (CSS) in FTC. Telomerase reverse transcriptase (TERT) promoter mutations associated with tumor aggressiveness. Thus, it could be a potential prognostic marker. The aim of this study was refine the CSS risk prediction using TERT combination fourth edition World Health Organization (WHO 2017) morphological...
BackgroundThyroid-stimulating hormone (TSH)-secreting pituitary neuroendocrine tumor (TSH PitNET) is a rare subtype of Pit- NET. We investigated the comprehensive characteristics and outcomes TSH PitNET cases from single medical center. Also, we compared diagnostic methods to determine which showed superior sensitivity. MethodsA total 17 patients diagnosed with after surgery between 2002 2022 in Samsung Medical Center was retrospectively reviewed. Data on treatment were collected. The...
Distant metastasis is a poor prognostic factor in medullary thyroid carcinoma (MTC), but the significance of differentiating characteristics according to site distant remains unclear. This study aimed evaluate clinical and long-term oncologic outcomes MTC patients with metastasis. We identified 46 between 1994 2019. Clinical were compared based on timing detection Additionally, survival rates following evaluated compare metastatic site. The detailed causes death also investigated. Of...
Background: Thyroid-stimulating hormone (TSH)-secreting pituitary neuroendocrine tumor (TSH PitNET) is a rare subtype of PitNET. We investigated the comprehensive characteristics and outcomes TSH PitNET cases from single medical center. Also, we compared diagnostic methods to determine which showed superior sensitivity.Methods: A total 17 patients diagnosed with after surgery between 2002 2022 in Samsung Medical Center was retrospectively reviewed. Data on treatment were collected. The...
Abstract Current guidelines recommend total thyroidectomy with central lymph node dissection (CND) for patients medullary thyroid carcinoma (MTC). This study aimed to identify low-risk MTC who may be candidates lobectomy. We retrospectively reviewed underwent primary surgery at a tertiary referral center from 1998 2019. Eighty-five were enrolled, excluding tumor size > 2.0 cm. Among them, one (1.2%) patient had bilateral tumors. During median follow-up of 84 months, 12 the 85 experienced...
Background: Bone mineral density (BMD) testing is indicated for women aged 65 years, but screening strategies osteoporosis are controversial. Currently, there no study focusing on the BMD interval in Asian populations. The current aimed to evaluate estimated time osteoporosis.Methods: We conducted a of 6,385 subjects 50 years and older who underwent dual-energy X-ray absorptiometry more than twice at Samsung Medical Center as participants routine health checkup. Subjects were divided based...
Thyroid hormone abnormalities have been linked to antiseizure medications (ASMs). Oxcarbazepine is considered safer than carbamazepine because it induces the hepatic cytochrome P450 metabolic enzymes less does. However, limited data exist for influence of oxcarbazepine on thyroid function in children and adolescents. The objective this study was determine effect these patients.A total 162 pediatric patients with epilepsy who started first time between April 2003 May 2020 were enrolled....
Age at diagnosis (AAD) and telomerase reverse transcriptase (TERT) promoter mutations are prognostic factors in differentiated thyroid carcinoma (DTC), the prevalence of increases with AAD. Considering this correlation, we investigated whether an interaction between AAD is present mutation mediates effect on mortality rate DTC.The study included 393 patients DTC who were followed-up after thyroidectomy a single medical center Korea from 1994 to 2004. Multivariable Cox regression was used...
<title>Abstract</title> BACKGROUND Abdominal obesity is currently being investigated as an indicator of adiposity and cancer risk, its prevalence increasing in young women. This study aimed to examine whether cumulative abdominal exposure women was associated with the development endometrial cancer. METHODS We used data from South Korean National Health Insurance Service for aged 20–39 years who had completed four consecutive annual health examinations between 2009 2015 no history at...
Objective Previous reports suggest that a high body mass index (BMI) increases the risk of thyroid carcinoma. However, it remains unclear whether BMI is associated with BRAFV600E mutation. We aimed to assess an increased Design and Methods screened 6558 PTC patients who had undergone mutation testing between January 2009 December 2017. After exclusion, 6438 were enrolled. used logistic regression, restricted cubic spline plots adjusted odds ratios (ORs) illustrated model relationship Results...
Thyroxine-binding globulin (TBG) is a major transporter protein for thyroid hormones. The serpin family A member 7 (SERPINA7) gene codes TBG, and mutations of the SERPINA7 result in TBG deficiency. Although more than 40 have been reported several countries, only few studies deficiency mutation performed Korea. aim this study to review clinical presentations laboratory findings patients with investigate types mutation.Five unrelated Korean adults attending endocrinology clinic underwent...
women with bipolar disorder based on observations that testosterone may affect mood and suicidality.We examined whether is related to the course of illness at baseline blood levels predict suicide attempts follow-up.Methods: Females a DSM-IV diagnosis in depressive or mixed episode least one past attempt were enrolled.We limited this study previous attempters order have higher risk group for follow-up thus sufficient power allow detection relationship clinical variables.Demographic...
Anxious depression, defined as major depressive disorder (MDD) accompanied by high levels of anxiety, seems to be difficult treat with traditional antidepressant monotherapy.The purpose this study was assess the efficacy ziprasidone monotherapy in patients anxious depression versus non-anxious depression.One hundred and twenty outpatients were enrolled a 12-week that divided into two 6-week periods according sequential parallel comparison design.Patients randomized 2:3:3 multi-ratio receive...