A5030590594- Acute Myeloid Leukemia Research
- Hemophilia Treatment and Research
- Platelet Disorders and Treatments
- Acute Lymphoblastic Leukemia research
- Lung Cancer Treatments and Mutations
- Cancer Treatment and Pharmacology
- Carcinogens and Genotoxicity Assessment
- Lung Cancer Research Studies
- Cancer-related gene regulation
- Cancer survivorship and care
- Advanced MRI Techniques and Applications
- Cancer and Skin Lesions
- Cancer Genomics and Diagnostics
- Pharmaceutical Practices and Patient Outcomes
- Liver Disease and Transplantation
- Cancer-related Molecular Pathways
- Pneumocystis jirovecii pneumonia detection and treatment
- Lymphoma Diagnosis and Treatment
- Childhood Cancer Survivors' Quality of Life
- Neurological and metabolic disorders
- DNA Repair Mechanisms
- Cancer Immunotherapy and Biomarkers
- Nutrition and Health in Aging
- Uterine Myomas and Treatments
- Ultrasound and Hyperthermia Applications
University of North Carolina at Chapel Hill
2025
Texas A&M Health Science Center
2024
Methodist Hospital
2023
Christiana Care Health System
2016-2022
Medical Oncology Hematology Consultants
2022
North Carolina State University
2019
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2017
University of Milan
2017
Leiden University Medical Center
2017
Roswell Park Comprehensive Cancer Center
2006-2011
ABSTRACT Background Historically, patients with human immunodeficiency virus (PWH) were at higher risk for pulmonary morbidities than without HIV. Lung transplantation in PWH has been limited by uncertain outcomes and a lack of guidelines immunosuppression. However, several case reports the United States Europe have demonstrated that lung is feasible. Although there remain concerns regarding these as higher‐risk recipients, feasible careful modification immunosuppression close monitoring....
Axillary metastasis from an occult breast carcinoma is uncommon presentation and presents a therapeutic dilemma. The objective of this study to describe the presenting clinical features, management approach treatment outcomes for carcinoma. We conducted retrospective review patients who presented with axillary nodal metastases between 1997 2004 at Roswell Park Cancer Institute; 2,150 were diagnosed treated cancer during period. After excluding stage I IV patients, we identified 642 had...
Summary. Menorrhagia at the time of menarche is relatively common and historically attributed primarily to immaturity pituitary–ovarian–uterine axis. Intuitively, a proportion these patients should have an underlying disorder haemostasis, given 5–20% prevalence von Willebrand’s disease ≥20% platelet dysfunction in light recent epidemiological studies menorrhagia, although average age those has been ∼35 years. However, there are few comprehensive adolescent population determining whether...
Abstract Smoking adversely affects hematopoietic stem cell transplantation outcome. We asked whether smoking affected outcome of newly diagnosed acute myeloid leukemia (AML) patients treated with chemotherapy. Data were collected on 280 AML high‐dose cytarabine and idarubicin‐containing regimens at Roswell Park Cancer Institute who had status data diagnosis. Patients' gender, age, presentation ( de novo vs . secondary), white blood (WBC) count diagnosis, karyotype (never ever) analyzed....
TPS1127 Background: Patients with metastatic triple-negative breast cancer (mTNBC) have a poor prognosis. Treatment combinations of anti-programmed death ligand 1 (anti–PD-L1) agents chemotherapy shown promise in mTNBC. LV is an investigational antibody–drug conjugate directed to LIV-1, protein highly expressed on cells, via humanized IgG1 monoclonal antibody conjugated monomethyl auristatin E (MMAE) by protease-cleavable linker. LIV-1–mediated delivery MMAE disrupts microtubules and induces...
Myoglobin cast nephropathy occurs in cases of acute renal injury which large amounts myoglobin accumulate the tubules, presenting as muscle pain, reddish-brown urine, and elevated creatine kinase levels. Our case describes a 60-year-old male who came to emergency department with fevers, mild abdominal constitutional symptoms one day after returning United States from trip Nigeria. Initial workup demonstrated an kidney aminotransferase levels patient was started onatovaquone-proguanil for...
Abstract Purpose: Early discontinuation or non-adherence of AI therapy occurs in 25-50 % patients due to treatment associated toxicities, including musculoskeletal symptoms such as arthralgias and myalgias. The goal this pilot study is evaluate the effect a directed physical regimen joint mobility stretching exercises on resulting from therapy, comparison normal activity alone. Patients methods: Eligibility criteria included post-menopausal women with histological evidence hormone receptor...
Low blood SNR makes detecting small vessels, measuring slow flow rates, and assessing perfusion without contrast administration challenging. A potential approach is to use Variance of Acceleration (VoA) imaging, which has been demonstrated previously in humans vivo for monitoring subcutaneous bleeding delineating intraplaque hemorrhage. We hypothesize that, the addition agents, VoA can detect vessels assessment. Experiments were performed on an ATS 700-D 527 calibrated phantom (vessel...
Geriatric assessment (GA) is recommended for evaluating fitness of an older adult with cancer. Our objective was to prospectively evaluate the gaps that exist in adults metastatic breast cancer (OA-MBC) community practices (CP).Self-administered GA compared provider's (PA) patients living MBC aged ≥65 years treated CP Providers were blinded results until PA completed. McNemar's test used detect differences between and GA.One hundred enrolled across 9 (median age 73.9). detected a total 356...
Flea-borne typhus (FBT), an uncommon illness in the United States, typically presents as a high continuous fever with commonly associated symptoms including headache, myalgias, and rashes on trunk extremities. Patients infected FBT may also present atypical symptoms. As such, combination of its relatively low incidence States coupled variability poses diagnostic challenge for clinicians; early empiric treatment doxycycline is warranted prior to definitive diagnosis reduce risk damage vital...
10630 Background: ERα promotes cell proliferation in breast tumors whereas p53 impedes cycle progression. We have reported direct link between these two opposing pathways. Our preclinical studies demonstrated that binds directly to and negatively regulates its function anti estrogens disrupted the ERα- interaction. Previous retrospective by us others advanced cancer patients had shown presence of wild type ER+ve is associated with better response endocrine therapy. Objective: To demonstrate...