- Legionella and Acanthamoeba research
- Antimicrobial Resistance in Staphylococcus
- Bacterial biofilms and quorum sensing
- COVID-19 Clinical Research Studies
- Water Treatment and Disinfection
- Peripheral Artery Disease Management
- Microbial infections and disease research
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- Wound Healing and Treatments
- Immunodeficiency and Autoimmune Disorders
- Orthopedic Infections and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Infectious Diseases and Tuberculosis
- Dermatological and COVID-19 studies
- Acute Ischemic Stroke Management
- Bacterial Identification and Susceptibility Testing
- HIV/AIDS Research and Interventions
- Sepsis Diagnosis and Treatment
- Salmonella and Campylobacter epidemiology
- Cystic Fibrosis Research Advances
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- T-cell and Retrovirus Studies
- Fungal Infections and Studies
- Nosocomial Infections in ICU
Hospital Universitari Germans Trias i Pujol
2001-2025
Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol
2020-2025
Universitat Autònoma de Barcelona
2001-2024
Hospital Universitari de Vic
2010-2023
Clinical Trial Investigators
2022
Fundació Lluita contra les Infeccions
2020-2021
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2020
Engineering Associates (United States)
2018
Servicio Geológico Minero Argentino
2009
Hospital Terrassa
2007
Fifty-seven patients developed an episode of catheter-related infection (CRI) in the bloodstream during their stay intensive care unit (cases) and were prospectively observed to establish attributable mortality, increase length stay, excess costs. Costs estimated by multiplying number days reimbursement provided. The outcomes for these cases compared with those matched control subjects without CRI. Eight excluded as no was found. Of 49 cases, 31 coagulase-negative staphylococci (CNS). level...
Staphylococcus caprae is a coagulase-negative staphylococcus commonly associated with animals which can also be zoonotic human pathogen. To date, there little data available on S. infections. The aim of this study was to characterize the infections identified in two hospitals located, respectively, rural and urban areas Catalonia, Spain. In retrospective, observational study, were compiled from clinical records all diagnosed between January 2010 December 2023. Over period, altogether 31...
A livestock-associated clonal lineage (ST398) of methicillin-resistant Staphylococcus aureus (MRSA) has been identified causing colonization or infection in farm workers. The aim the study was to analyze prevalence MRSA-ST398 pigs and pig farmers an area with a high population (Osona, Barcelona province, Catalonia, Spain). We performed cross-sectional Osona (Catalonia, Spain), from June 2014 2015. All workers 83 farms were studied. Twenty these randomly selected for both farmers: 9 fattening...
Tetracycline resistance (TetR) is a marker of livestock-associated MRSA lineage CC398.To determine the CC398 prevalence among TetR-MRSA recovered in Spanish hospitals located regions with different pig-farming densities, and influence pig density as key risk factor for its acquisition.TetR-MRSA isolates (n = 232) from clinical epidemiological samples during January-June 2016 20 13 densities were analysed. identification, detection spa types, methicillin genes immune evasion cluster (IEC)...
Tedizolid has demonstrated its efficacy and safety in clinical trials; however, data concerning tolerability long-term treatments are scarce. The aim of the study was to assess indications describe profile tedizolid. A multicentric retrospective patients who received tedizolid for more than 6 days conducted. Adverse events (AEs) were identified from patients’ medical records laboratory data. World Health Organization causality categories used discern AEs that probably associated with
Abstract Objective: To determine whether environmental cultures for Legionella increase the index of suspicion legionnaires' disease (LD). Design: Five-year prospective study. Setting: Twenty hospitals in Catalonia, Spain. Methods: From 1994 to 1996, potable water systems 20 Catalonia were tested , Cases hospital-acquired LD and availability an “in-house” test previous 4 years assessed. After informed results their cultures, a 5-year-study was conducted focusing on detection new cases...
An HIV incidence estimation was performed among men who have sex with (MSM), drug users (DUs), workers (SWs), and pregnant women (PW) from Argentina. Volunteers older than 18 years old without a previous HIV-positive diagnosis were included. samples analyzed by the Serological Testing Algorithm for Recent Seroconversion (STARHS) to estimate incidence. By partial RT-PCR sequencing of pol gene, an subtype resistance profile determined. A total 12,192 volunteers recruited October 2006 September...
Background: To evaluate the efficacy and safety of long-term use tedizolid in osteoarticular infections. Methods: Multicentric retrospective study (January 2017–March 2019) infection cases treated with tedizolid. Failure: clinical worsening despite antibiotic treatment or need suppressive treatment. Results: Cases (n = 51; 59% women, mean age 65 years) included osteoarthritis 27, 53%), prosthetic joint 17, 33.3%), diabetic foot infections 9, 18%); where, were orthopedic device-related. Most...
The objective of this study was to compare epidemiological data and clinical presentation community-acquired pneumonia (CAP) caused by Streptococcus pneumoniae, Legionella pneumophila or Chlamydia pneumoniae. From May 1994 February 1996, 157 patients with S. pneumoniae (n=68), L. (n=48) C. (n=41) definitive diagnosis, were prospectively studied. following comparisons showed differences at a level least p<0.05. Patients had more frequently underlying diseases (HIV infection neoplasm) those...
Background: To date, there is little information regarding management of patients with infective endocarditis (IE) that did not undergo an indicated surgery. Therefore, we aimed to evaluate prognosis these treated a long-term antibiotic treatment strategy, including oral long term suppressive in five referral centres multidisciplinary team. Methods: This retrospective, multicenter study retrieved individual patient-level data from Spain. Among total 1797, 32 consecutive IE were examined...
Background Disseminated tuberculosis is frequently associated with delayed diagnosis and a poorer prognosis. Objectives To describe case series of disseminated TB delay in low burden country during the COVID-19 period. Methodology We consecutively included all patients reported from 2019 to 2021 reference hospital Northern Crown Metropolitan Area Barcelona. collected socio-demographic information, clinical, laboratory radiological findings. Results 30 study period—5, 9, 16 2019, 2020,...
To investigate the presence and clonal distribution of Legionella species in water supply 20 hospitals Catalonia, Spain.20 an area 32,000 km2, located northeast Spain.Environmental cultures 186 points potable 10 cooling towers were performed for species. Following filtration acid treatment, samples seeded selective MWY (modified Wadowsky Yee)-buffered charcoal yeast extract-alpha agar. All isolates obtained characterized microbiologically genotyped by SfiI pulsed-field gel electrophoresis...
Methicillin-resistant S. aureus (MRSA) especially ST398, is a zoonotic agent. This study aimed to determine the prevalence of methicillin-susceptible (MSSA) and MRSA among workers in pork production chain. 659 associated with 123 pig farms, livestock transporters, one slaughterhouse, transporters 23 butcheries were studied for recovery, all isolates characterized (antibiotic resistance, MLST spa-typing). The was 35.5%, 75.6% being MRSA. 68.7% (149/217) farm, 33.9% (19/56) 2.9% (9/306) 0%...
We evaluated the impact of copper-silver ionization system in a hospital where hyperendemic nosocomial legionellosis and was present all previous disinfection measures had failed. After implementation system, environmental colonization with Legionella species decreased significantly, incidence dramatically, from 2.45 to 0.18 cases per 1000 patient discharges.
The use of high-dose intravenous immunoglobulins (IVIGs) as immunomodulators for the treatment COVID-19–affected individuals has shown promising results. IVIG reduced inflammation in these patients, who progressively restored respiratory function. However, little is known about how they may modulate immune responses COVID-19 individuals. Here, we have analyzed levels 41 inflammatory biomarkers plasma samples obtained at day 0 (pretreatment initiation), 3, 7, and 14 from five hospitalized...
Abstract Objective: To determine whether environmental cultures for Legionella increase the index of suspicion legionnaires' disease (LD). Design: Five-year prospective study. Setting: Twenty hospitals in Catalonia, Spain. Methods: From 1994 to 1996, potable water systems 20 Catalonia were tested , Cases hospital-acquired LD and availability an “in-house” test previous 4 years assessed. After informed results their cultures, a 5-year-study was conducted focusing on detection new cases...
MRSA nasal carriage was detected in 15.7% of 204 residents from 6 nursing homes (NHs) the Osona region (Barcelona, Spain), and MRSA-ST398 lineage identified 15.6% MRSA-positive 2.5% all NH evaluated. Most carriers (4 5) had direct or indirect contact with pig farms. Infect Control Hosp Epidemiol 2018;39:90–93
Inhalation of contaminated aerosols is considered the most common route Legionella transmission. The aim this study was to determine whether contact with water by related oropharyngeal colonization in immunosuppressed patients. Eighty-five swabs (April 1996 June 1996) were seeded on selective and nonselective buffered charcoal-yeast extract media. not isolated.