A5062371178- Breast Lesions and Carcinomas
- Advanced X-ray Imaging Techniques
- Lymphoma Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Salivary Gland Tumors Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Cancer and Skin Lesions
- Tumors and Oncological Cases
- Tracheal and airway disorders
- Neuroendocrine Tumor Research Advances
- Sarcoma Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Polyomavirus and related diseases
- Medical Imaging Techniques and Applications
- Viral-associated cancers and disorders
- HER2/EGFR in Cancer Research
- CNS Lymphoma Diagnosis and Treatment
- Myasthenia Gravis and Thymoma
- Digital Holography and Microscopy
- Genetic factors in colorectal cancer
- Lung Cancer Treatments and Mutations
- Oral and Maxillofacial Pathology
- Cancer, Hypoxia, and Metabolism
- Chronic Lymphocytic Leukemia Research
- Cancer Cells and Metastasis
Nagoya Medical Center
2014-2025
National Hospital Organization
2015-2025
Clinical Research Management
2022
Aichi Cancer Center
2021
Higashi Nagoya National Hospital
2021
Aichi Medical University
2019
Aichi Medical University Hospital
2019
Nagoya University
2010-2013
Glandular papilloma (GP) and mixed squamous cell glandular (MP) are rare benign pulmonary tumors occurring in the bronchi. Bronchiolar adenoma (BA) was recently characterized as a tumor exhibiting alveolar spread. Both GP/MP BA composed of mixture glandular, ciliated, squamous, basal cells. We aimed to clarify whether represent same tumor. evaluated detailed histologic characteristics 11 cases involving peripheral that exhibited features or BA, performed genetic analyses using targeted panel...
Abstract An emerging group of spindle cell neoplasms harboring fusions involving NTRK or non‐ kinase genes often share characteristic S100 and/or CD34 expression; however, the diagnostic utility immunohistochemical stains is not well established in this family owing to their lack specificity. Recently, CD30 expression with gene fusions, such as , BRAF RAF1 and RET has been increasingly identified. We herein report a 10‐year‐old girl high‐grade sarcoma neck. Prior histopathological...
The RET finger protein (RFP) is a transcription factor belonging to the TRIM (tripartite motif) superfamily of proteins. RFP expressed in variety human and rodent tumor cell lines several kinds cancer. Expression associated with prognosis colon endometrial cancers. In present study, we evaluated expression lung cancer assessed its clinical significance. Tissue microarrays were constructed from 108 cases cancer, sections analyzed for by immunohistochemistry. was detected nucleus 66.7% tissues...
Solitary fibrous tumor (SFT) is usually an indolent neoplasm with a low rate of local recurrence and metastasis. Although dedifferentiation low‐grade sarcoma well documented, the concept dedifferentiated SFT was not recognized until recently. A case intracranial seven recurrences within 5 years, showing progression during course disease, reported here. 51‐year‐old woman history irradiation infancy presented in right posterior fossa. Because close proximity to brain stem, could be removed...
Thoracic SMARCA4-deficient undifferentiated tumor (SMARCA4-UT) is a recently recognized characterized by inactivation of SMARCA4, SWItch/Sucrose NonFermentable chromatin remodeler, detectable immunohistochemistry. SMARCA4-UT shows or rhabdoid morphology with claudin-4 negativity. However, thoracic tumors the same histologic features as SMARCA4-UTs but preserved SMARCA4 expression have so far been underrecognized. We herein report 3 cases isolated loss SMARCA2 retained and SMARCB1. The...
Hepatocyte nuclear factors (HNF) 6 and 4α are master transcriptional regulators of development maintenance the liver pancreaticobiliary tract in mice humans. However, little is known about prevalence HNF6 HNF4α expression carcinomas hepatobiliary pancreas. We aimed to reveal diagnostic utility immunolabelling adenocarcinomas these organs. investigated by immunohistochemistry using a total 480 digestive system, including 282 pancreas 198 gastrointestinal tract. was primarily restricted...
To clarify the diagnostic clues of ductal carcinomas in situ (DCIS) associated with papilloma and optimal clinical management diagnosed on core needle biopsy (CNB).A total 50 surgically resected cases were examined histopathologically topographically. Thirty-nine (78%) spread segmental fashion. Papilloma DCIS intermingled closely 44 (88%), occupying same areas varying proportions from DCIS-predominant to papilloma-predominant. The two components occupied discrete collided focally six (12%)....
Idiopathic orbital inflammation (IOI) is a group of inflammatory diseases unknown etiopathogenesis. We investigated whether patients with IOI have clinical heterogeneity based on the presence (typical group) or absence (atypical unique onset that periocular symptoms emerge suddenly but progress slowly.This retrospective cohort study included 195 diagnosed IOI. analysed data patients, including outcomes corticosteroid treatment, in two subgroups stratified basis (130 patients) (65...
We herein report a case of myasthenia gravis (MG) in which thoracoscopic thymectomy was performed for large thymic cystic lesion using subxiphoid approach. have previously suggested the usefulness approach thymectomy. The indications were recently expanded to include lesions without intraoperative rupture lesions. pathologic diagnosis present multilocular cyst with type A thymoma and micronodular thymoma. postoperative complications minimal MG crisis. Thoracoscopic seems be an ideal...
Although several reports have highlighted neoplastic PD‐L1 (nPD‐L1) expression in classic Hodgkin lymphoma (CHL), some addressed associations between its and detailed histopathologic features. Here we describe four cases of syncytial variant CHL (SV‐CHL), with without Epstein–Barr virus (EBV) association, highlight the diagnostic utility (clone SP142) immunohistochemistry. The patients were a 61‐year‐old male, 45‐year‐old 85‐year‐old female, 89‐year‐old female. All presented cervical or...
Background: There are no established guidelines for the management of apocrine carcinomas breast; they treated as a non-specific type breast cancer. Case Report: We report on case 40-year-old man who developed primary mediastinal carcinoma overexpressing human epidermal growth factor-2 (HER2). The patient initially underwent complete resection mature teratoma with focal component. Two years after surgery, relapse was detected in multiple lymph nodes. He received induction chemotherapy...
Composite lymphoma is a well-known diagnostic entity exhibiting the synchronous occurrence of two or more distinct types lymphomas in same specimen. Here we report patients, 14-year-old female (Case 1) and 45-year-old male 2), with mediastinal composite lymphoma, comprising nodular sclerosis classic Hodgkin (NSCHL) primary large B-cell (PMBL). Both patients had mass, manifested different histologic components biopsy, one characteristic NSCHL other PMBL. The areas included Reed-Sternberg...