A5003897225- Intracranial Aneurysms: Treatment and Complications
- Retinal Diseases and Treatments
- Meningioma and schwannoma management
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Head and Neck Surgical Oncology
- Vascular Malformations Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Glioma Diagnosis and Treatment
- Cerebrospinal fluid and hydrocephalus
- Neurofibromatosis and Schwannoma Cases
- Intraoperative Neuromonitoring and Anesthetic Effects
- Retinal and Optic Conditions
- Cerebrovascular and Carotid Artery Diseases
- Retinal and Macular Surgery
- Ocular Diseases and Behçet’s Syndrome
- Neurosurgical Procedures and Complications
- Cerebral Venous Sinus Thrombosis
- Oral and Maxillofacial Pathology
- Ocular Oncology and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Moyamoya disease diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Adrenal and Paraganglionic Tumors
Fukushima Medical University
2014-2023
Essen University Hospital
2018-2023
Deutschen Konsortium für Translationale Krebsforschung
2023
University of Duisburg-Essen
2018-2023
Erwin L. Hahn Institute for Magnetic Resonance Imaging
2018-2022
National Hospital Organization
2018-2020
Sendai Medical Center
2020
Tokushima Red Cross Hospital
2018
Nara Medical University
2018
Kyorin University
2018
In Brief Purpose: To identify the tomographic features of branching vascular networks in patients with polypoidal choroidal vasculopathy (PCV). Methods: We prospectively performed third-generation optical coherence tomography (OCT) and fluorescein angiography for 44 eyes 42 (mean age ± SD, 67.1 9.1 years) PCV. All had lesions that were confirmed by indocyanine green angiography. Results: OCT showed double reflective layers consisted retinal pigment epithelium (RPE) another highly layer...
To obtain a clinically useful method of intraoperative monitoring visual evoked potentials (VEPs), the authors developed new light-stimulating device and introduced electroretinography (ERG) to ascertain retinal light stimulation after induction venous anesthesia.The stimulating consists 16 red light-emitting diodes embedded in soft silicone disc avoid deviation axis frontal scalp-flap reflection. After anesthesia with propofol, performed ERG VEP recording 100 patients (200 eyes) who were at...
Optical coherence tomography (OCT) abnormalities of age-related macular degeneration (AMD) have not been fully characterized because the complex morphology and a lack correlative histologic studies. Expansion our ability to interpret increasing attributes brings us closer goal in vivo analysis eye by OCT.To describe new outer retinal finding AMD using spectral-domain (SD) OCT suggest histopathologic correlates.Twenty-five eyes 16 patients with severe atrophy due either choroidal...
<h3>BACKGROUND AND PURPOSE:</h3> The pathophysiology of wall contrast enhancement in thrombosed intracranial aneurysms is incompletely understood. This vivo study aimed to investigate microstructures with gadolinium-enhanced 7T MR imaging. <h3>MATERIALS METHODS:</h3> Thirteen patients 14 were evaluated using a whole-body imaging system nonenhanced and high-resolution MPRAGE. Tissue samples available 5 cases, histopathologic findings correlated identify the gadolinium-enhancing...
Object Dysphasia is one of the most serious complications skull base surgeries and results from damage to brainstem and/or cranial nerves involved in swallowing. Here, authors propose a method monitor function vagus nerve using endotracheal tube surface electrodes transcranial electrical stimulation during surgeries. Methods Fifteen patients with or tumors were enrolled. The used an record compound electromyographic responses vocalis muscle. Motor neurons stimulated corkscrew placed...
To investigate the interactions among drusen type and multimodal vision testing in eyes with nonexudative age-related macular degeneration.Fifty-one of 39 patients degeneration underwent fundus imaging including spectral domain optical coherence tomography, color photograph, autofluorescence imaging, each which was graded by 2 masked readers. Multimodal included visual acuity using Early Treatment Diabetic Retinopathy Study protocol refraction, contrast sensitivity,...
To evaluate the effects of aflibercept therapy using a treat-and-extend regimen on treatment-naïve retinal angiomatous proliferation (RAP) and development pigment epithelium (RPE) atrophy.We retrospectively studied 17 treated eyes with RAP 13 untreated fellow eyes. We assessed best-corrected visual acuity (BCVA) in logarithm minimal angle resolution (logMAR) units recorded total number injections for 12 months. Central macular thickness (CMT) central choroidal (CCT) were by optical coherence...
In Brief Purpose: To investigate the interactions among multimodal imaging findings and vision testing in neovascular age-related macular degeneration. Methods: Patients enrolled a prospective study of degeneration with at least 3 previous intravitreal anti-vascular endothelial growth factor injections. Each patient underwent fundus including spectral domain optical coherence tomography autofluorescence, testing, visual acuity, contrast sensitivity, reading speed, microperimetry. Results:...
In Brief Purpose: To investigate repair mechanisms of retinal pigment epithelial (RPE) tears in age-related macular degeneration. Methods: The authors retrospectively studied 10 eyes with degeneration that developed RPE during follow-up or after treatment an anti-vascular endothelial growth factor drug photodynamic therapy combined ranibizumab. After development the tears, all follow-ups exceeded 13 months. Spectral domain swept-source optical coherence tomography have been used to examine...
The purpose of this study was to investigate the clinical characteristics a hyporeflective space between hyperreflective materials in pigment epithelial detachment (PED) and Bruch's membrane neovascular age-related macular degeneration (AMD) using spectral-domain optical coherence tomography (SD-OCT) or swept source (SS-OCT). Among 223 patients with AMD, 227 eyes were studied retrospectively. Using SD-OCT SS-OCT, we reviewed space. Twenty-two (10%) showed PED membrane. In all spaces,...
The authors report the in vivo visualization through multimodal imaging of silicone oil vitreous cavity, optic nerve, and retina a patient 11 years after surgical removal main tamponade. Contact B-scan ultrasonography revealed countless small echogenic particles cavity hyperreflective structure within nerve head. Swept-source optical coherence tomography showed multiple round hyporeflective spaces substance prelaminar Adaptive optics numerous head same plane as photoreceptors, with similar...
We conducted a genome-wide association study (GWAS) on the outcome of anti-VEGF treatment for exudative age-related macular degeneration (AMD) in prospective cohort. Four hundred and sixty-one treatment-naïve AMD patients were recruited at 13 clinical centers all treated with 3 monthly injections ranibizumab followed by pro re nata regimen one year. Genomic DNA was collected from 2-stage GWAS achieving dry macula after initial treatment, requirement an additional visual acuity changes during...
In Brief Purpose: The purpose of this study was to define the origin intraretinal neovascularization in retinal angiomatous proliferation with spectral domain-optical coherence tomography. Methods: We retrospectively studied nine consecutive eyes seven patients (two two men, five women) untreated using fluorescein and indocyanine green angiography One eye had stage I disease, II disease no pigment epithelial detachment, six detachment. evaluated location neovascularization, disruption...
Background and Objective: Skull base chordomas are clinically malignant because of the difficulty total removal, high recurrence rate, occasional drop metastasis. Although aggressive surgical resection postoperative radiation have been recommended, long-term outcome remains unsatisfactory.Methods: From 1992 to 2011, we treated 24 patients with skull chordoma using removal as a principal strategy. approaches were selected according tumor extension remove surrounding bone completely possible....
In Brief Purpose: To correlate optical coherence tomography (OCT) with angiographic signs of choroidal neovascularization (CNV) in retinal pigment epithelial detachment (PED) associated age-related macular degeneration (ARMD). Methods: Prospectively, the authors performed OCT 35 eyes patients (30 men and 5 women a mean age 71.6 years [range, 56–76 years]) ARMD. All had CNV area PED or adjacent to it, which was shown by fluorescein indocyanine green angiography. Cross-sectional images were...
Histological evaluation of dissecting aneurysms the cerebral arteries has suggested that defects in internal elastic lamina (IEL) induce dissection arterial wall. Dissecting occur most frequently vertebral artery (VA). The present study examined sections normal VA to elucidate mechanisms dissection. Bilateral VAs (20 vessels) were obtained from 10 patients who died causes other than intracranial lesions. detached union site mm proximal point penetrating dura mater. cut at 5-mm intervals, and...