A5039756612- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Hepatitis C virus research
- Cardiac Arrhythmias and Treatments
- Gastrointestinal disorders and treatments
- Renal Transplantation Outcomes and Treatments
- Atrial Fibrillation Management and Outcomes
- Liver Diseases and Immunity
- Hepatitis B Virus Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Congenital Heart Disease Studies
- Cardiac pacing and defibrillation studies
- Drug-Induced Hepatotoxicity and Protection
- Celiac Disease Research and Management
- Electrolyte and hormonal disorders
- Sarcoidosis and Beryllium Toxicity Research
- Gastrointestinal Bleeding Diagnosis and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Parvovirus B19 Infection Studies
- Polyomavirus and related diseases
- Autoimmune and Inflammatory Disorders
- Cardiac Imaging and Diagnostics
- Cardiovascular Syncope and Autonomic Disorders
- Pancreatitis Pathology and Treatment
University of Cincinnati Medical Center
2016-2025
University of Cincinnati
2009-2024
Cincinnati Children's Hospital Medical Center
2024
Sabin Vaccine Institute
2020
University of Michigan
2014-2016
VA Connecticut Healthcare System
2012-2014
Connecticut Health Foundation
2014
Yale University
2012-2014
Na Homolce Hospital
2010-2011
Wright State University
2009
Breakthroughs in hepatitis C virus (HCV) treatment and rising rates of intravenous drug use have led to an increase the number organ donors who are HCV antibody-positive but serum nucleic acid test (NAT)-negative. The risk transmission from liver grafts these recipients is unknown. To estimate incidence transmission, we prospectively followed 26 consecutive antibody-negative (n = 25) or NAT-negative 1) transplant received a graft were between March 2016 2017. was considered occurred if...
Objective: To assess agreement between abdominal ultrasound and MRI for the detection of focal liver lesions manifestations portal hypertension in patients with Fontan circulation. Materials Methods: perform this single-center, retrospective study, we identified circulation who underwent clinical examinations within ±12 months January 1, 2018 June 30, 2023. Imaging reports were reviewed presence (specifically noting >1 cm radiologist-indicated suspicious lesions), features (ie, ascites...
Many prognostic studies in cirrhosis were performed without distinguishing between compensated and decompensated patients and/or have evaluated the role of variables that are not routinely used. The aim was to evaluate predictors survival separately but a concurrent cohort focused on routine clinical variables.Secondary analysis prospective with collected tertiary center August 2000 May 2002 followed until death or April 2006. Univariate, stratified univariate analysis, multivariate Cox...
Obesity has become an epidemic in the United States over past decade, and recent studies have shown this trend liver transplantation (LT) population. These patients may be candidates for laparoscopic sleeve gastrectomy (LSG) to promote significant sustained weight loss prevent recurrence of nonalcoholic steatohepatitis. However, safety remains a concern, efficacy setting is uncertain. A single‐institution database from 2014 2018 was queried undergoing LSG following LT. The selection criteria...
Objectives: The aim of this study was to assess the 1-year safety and effectiveness HBV Nucleic Acid Test positive (HBV NAT+) allografts in seronegative kidney transplant (KT) liver (LT) recipients. Summary Background Data: Despite an ongoing organ shortage, utilization NAT+ into recipients has not been investigated. Methods: From January 2017 October 2020, a prospective cohort conducted among consecutive KT LT at single institution. Primary endpoints were post-transplant viremia, graft...
Because of underutilization liver allografts, our center previously showed that hepatitis C virus (HCV) antibody–positive/nucleic acid test (NAT)–negative livers when transplanted into HCV nonviremic recipients were safe with a 10% risk transmission. Herein, we present single‐center prospective experience using NAT+ allografts NAT– recipients. An institutional review board–approved matched cohort study was conducted examining post– transplantation (LT) outcomes HCV– patients who received...
Histoplasmosis is endemic to the midwestern and east central states in United States near Mississippi Ohio River valleys. Ninety-nine percent of patients exposed histoplasmosis develop only subclinical infection. Liver involvement as a part disseminated well known; however, isolated hepatic without any other stigmata dissemination extremely rare literature limited two case reports. We present granulomatous hepatitis due 35-year-old female with dermatomyositis receiving low-dose prednisone...
Despite adverse effects like hyperglycemia, new‐onset diabetes after transplant (NODAT), and infectious complications, corticosteroid use remains an important part of liver transplantation (LT) immune suppression. Budesonide, a synthetic corticosteroid, undergoes extensive first‐pass hepatic metabolism with only 10% systemic bioavailability, providing opportunity for improved toxicity‐therapeutic ratio. Although effective in the treatment autoimmune hepatitis, budesonide LT suppression are...
A 48-year-old female developed acute emphysematous cholecystitis after an endoscopic retrograde cholangiopancreatography (ERCP) for evaluation of sphincter Oddi dysfunction. Cholecystectomy was performed 2 days later. Cultures grew Clostridium perfringens. The patient received broad-spectrum antibiotics but recurrent cholangitic abscesses and intra- extra-hepatic biliary necrosis. She managed by percutaneous transhepatic drains. For next 3 years, had episodes obstruction, cholangitis,...