A5081616336- Plant Molecular Biology Research
- Plant Gene Expression Analysis
- Plant nutrient uptake and metabolism
- Photosynthetic Processes and Mechanisms
- Plant Reproductive Biology
- Bioinformatics and Genomic Networks
- Plant Stress Responses and Tolerance
- Polysaccharides and Plant Cell Walls
- Lipid metabolism and biosynthesis
- Microbial Metabolic Engineering and Bioproduction
- Genetic Mapping and Diversity in Plants and Animals
- Plant biochemistry and biosynthesis
- Plant tissue culture and regeneration
- Computational Drug Discovery Methods
- Biofuel production and bioconversion
- Genomics and Chromatin Dynamics
- Genomics, phytochemicals, and oxidative stress
- Light effects on plants
- Plant-Microbe Interactions and Immunity
- Fungal and yeast genetics research
- Genetic diversity and population structure
University of California, Davis
2011-2023
University of California, Berkeley
2019-2023
The cambium and procambium generate the majority of biomass in vascular plants. These meristems constitute a bifacial stem cell population from which xylem phloem are specified on opposing sides by positional signals. PHLOEM INTERCALATED WITH XYLEM (PXY) receptor kinase promotes division organization. However, how these functions integrated is unknown. Here, we mapped putative PXY-mediated transcriptional regulatory network comprising 690 transcription factor-promoter interactions Arabidopsis (
Lateral root primordia (LRP) originate from pericycle stem cells located deep within parental tissues. LRP emerge through overlying tissues by inducing auxin-dependent cell separation and hydraulic changes in adjacent cells. The auxin-inducible auxin influx carrier LAX3 plays a key role concentrating this signal LRP. Delimiting expression to two files new is crucial ensure that auxin-regulated occurs solely along their shared walls. Multiscale modeling has predicted highly focused pattern of...
Abstract A key unanswered question in plant biology is how a regulates metabolism to maximize performance across an array of biotic and abiotic environmental stresses. In this study, we addressed the potential breadth transcriptional regulation that can alter accumulation defensive glucosinolate metabolites Arabidopsis (Arabidopsis thaliana). systematic yeast one-hybrid study was used identify hundreds unique regulatory interactions with nearly complete complement 21 promoters for aliphatic...
In plants, many signalling molecules, such as phytohormones, miRNAs, transcription factors, and small peptides, drive growth development. However, very few peptides have been shown to be necessary for lateral root Here, we describe the role of peptide RALFL34 during early events in development, demonstrate its specific importance orchestrating formative cell divisions pericycle. Our results further suggest that this acts on transcriptional cascade leading a new upstream GATA23, an important...
Spatiotemporal regulation of transcription is fine-tuned at multiple levels, including chromatin compaction. Polycomb Repressive Complex 2 (PRC2) catalyzes the trimethylation Histone 3 lysine 27 (H3K27me3), which hallmark a repressive state. Multiple PRC2 complexes have been reported in Arabidopsis thaliana to control expression genes involved developmental transitions and maintenance organ identity. Here, we show that member display complex spatiotemporal gene patterns function root...
Determining the complete Arabidopsis (Arabidopsis thaliana) protein-protein interaction network is essential for understanding functional organization of proteome. Numerous small-scale studies and a couple large-scale ones have elucidated fraction estimated 300,000 binary interactions in Arabidopsis. In this study, we provide evidence that docking algorithm has ability to identify real using both experimentally determined predicted protein structures. We ranked 0.91 million generated by all...
Plant metabolism is more complex relative to individual microbes. In single-celled microbes, transcriptional regulation by single transcription factors (TFs) sufficient shift primary metabolism. Corresponding genome-level regulatory maps of reveal the underlying design principles responsible for these shifts as a model in which master regulators largely coordinate specific metabolic pathways. and specialized occur within innumerable cell types, their reactions depending on internal external...
Efficiently obtaining and utilizing energy elements is critical for an organism to maximize its fitness. Optimizing these processes requires precise regulation coordination of organism's metabolic networks in response diverse environmental conditions developmental stages. Metabolic often considered largely occur by allosteric feedback where the metabolites directly influence enzymes function. Recent work showing that there also extensive role transcriptional control enzyme encoding genes...
Abstract Regulation of plant root angle is critical for obtaining nutrients and water an important trait breeding. A plant’s final, long-term the net result a complex series decisions made by tip in response to changes nutrient availability, impediments, gravity vector other stimuli. When displaced from vector, short-term process gravitropism results rapid reorientation toward vertical. Here, we explore both short- regulation growth angle, using natural variation tomato identify shared...
Abstract Anthropogenic environmental changes create evolutionary pressures on populations to adapt novel stresses. It is as yet unclear, when respond these selective pressures, the extent which this results in convergent genetic evolution and whether convergence due independent mutations or shared ancestral variation. We address questions using a classic example of adaptation by natural selection investigating rapid colonization plant species Mimulus guttatus copper contaminated soils. use...
Summary In single-celled microbes, transcriptional regulation by single transcription factors is sufficient to shift primary metabolism. Corresponding genome-level regulatory maps of metabolism reveal the underlying design principles responsible for these shifts as a model in which master regulators largely coordinate specific metabolic pathways. Relative individual plant more complex. Primary and specialized occur within innumerable cell types, their reactions depending on internal external...
ABSTRACT Nitrogen is an essential element for all life processes in plants. As such, plant roots dynamically respond to nitrogen availability below-ground by executing a signaling and transcriptional cascade resulting altered growth, optimized nutrient uptake. The NIN-LIKE PROTEIN 7 (NLP7) transcription factor senses along with its closely related paralog NLP6, partially coordinates these responses. While post-translational regulation of NLP6/7 well established, upstream remains understudied...
Abstract Nitrogen (N) is an essential macronutrient and its bioavailability plays a major role in how plant development tuned to environmental nutrient status. To find novel factors early root system architecture responses N conditions, we performed Arabidopsis thaliana transcriptome profiling of short-term time course limiting sufficient conditions. Using this data, inferred transcriptional regulatory networks each condition, which revealed the N-condition specific jasmonate regulation;...